Experimental and modeling study of adsorption in preparative monolithic column

• Tipo: Artigo em Revista Científica Internacional
• Data: 2006

Autores

Michal Zabka (Autor) FEUP; Mirjana Minceva (Autor) FEUP; Alírio Rodrigues (Autor) FEUP

Revista

Título: Chemical Engineering and Processing - Process Intensification

Vol. 45 Nº 2

Páginas: 150-160

ISSN: 0255-2701

Editora: Elsevier

Indexação

ISI Proceedings

Classificação Científica

CORDIS: Ciências Tecnológicas > Engenharia > Engenharia química

Outras Informações

Resumo (PT): The hydrodynamic, equilibrium and kinetics of adsorption in a silica-based monolithic preparative column Chromolith Prep. Si (Merck KgaA, Germany) have been studied. The inverse size-exclusion chromatography with polystyrene standards of narrow molecular size distribution and small tracer molecule has been used to measure the external and total porosity of the monolithic column. The column permeability was calculated according to the Darcy law for laminar flow. The efficiency of the monolithic column was characterized through the height equivalent to a theoretical plate (HETP) of phenol, ethyl vanillin and dimethyl phthalate. The separation efficiency does not decrease in the region of high flow rates. The adsorption isotherms of phenol, ethyl vanillin and dimethyl phthalate measured by frontal analysis were linear in the investigated concentration range. The 2D single channel mathematical model has been applied to describe the adsorption dynamics. The model assumes parabolic velocity profile, axial and radial diffusion in the monolith channel, linear driving force model for the mass transfer in the monolith channel skeleton wall and linear adsorption equilibrium. The model gives good prediction of the experimental breakthrough curves. (c) 2005 Elsevier B.V All rights reserved.

Abstract (EN): The hydrodynamic, equilibrium and kinetics of adsorption in a silica-based monolithic preparative column Chromolith Prep. Si (Merck KgaA, Germany) have been studied. The inverse size-exclusion chromatography with polystyrene standards of narrow molecular size distribution and small tracer molecule has been used to measure the external and total porosity of the monolithic column. The column permeability was calculated according to the Darcy law for laminar flow. The efficiency of the monolithic column was characterized through the height equivalent to a theoretical plate (HETP) of phenol, ethyl vanillin and dimethyl phthalate. The separation efficiency does not decrease in the region of high flow rates. The adsorption isotherms of phenol, ethyl vanillin and dimethyl phthalate measured by frontal analysis were linear in the investigated concentration range. The 2D single channel mathematical model has been applied to describe the adsorption dynamics. The model assumes parabolic velocity profile, axial and radial diffusion in the monolith channel, linear driving force model for the mass transfer in the monolith channel skeleton wall and linear adsorption equilibrium. The model gives good prediction of the experimental breakthrough curves. (c) 2005 Elsevier B.V All rights reserved.

Idioma: Português

Tipo (Avaliação Docente): Científica