Effect of Some Natural Mineral Waters in Nutrient Uptake by Caco-2 Cells

• Tipo: Artigo em Revista Científica Internacional
• Data: 2010

Autores

Gonçalves P (Autor) FMUP; Araújo JR (Autor) FMUP; Martel, F (Autor) FMUP

Revista

Título: International Journal for Vitamin and Nutrition Research

Vol. 80

Páginas: 131-143

ISSN: 0300-9831

Editora: Hogrefe Publishers

Indexação

ISI Web of Knowledge - 3 Citações

Scopus - 4 Citações

Outras Informações

ID Authenticus: P-003-7TJ

DOI: 10.1024/0300-9831.000013

Abstract (EN): We studied the effect of some mineral waters and some of their constituents on the apical uptake of C-14-butyrate (C-14-BT) and H-3-O-methyl-D-glucose (H-3-OMG) by Caco-2 cells. Uptake of C-14-BT increased after a 20-minute exposure to 1 % (v/v) distilled water, and, compared to distilled water, it was decreased by Pedras Salgadas (R) 1 % (v/v) and Melgaco (R) 5 % (v/v), and increased by Vidago (R) 5 % (v/v). Moreover, it increased after a 48-hour exposure to Vidago (R) or Melgaco (R) waters (5 % (v/v)). Also, uptake of C-14-BT was reduced after a 20-minute exposure to MgCl2, MgSO4, or CaCl2. Uptake of H-3-OMG was reduced after a 20-minute exposure to Melgaco (R) water [1 % (v/v)], when compared to distilled water. Also, a 48-hour exposure to Pedras Salgadas (R) or Melgaco (R) water (5 % (v/v)) increased and decreased uptake, respectively. Finally, uptake of H-3-OMG decreased after a 20-minute exposure to MgSO4 or NaF. In conclusion, uptake of C-14-BT and H-3-OMG by Caco-2 cells is differently modulated by distinct mineral waters.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 13