What is the effect of a Mediterranean compared with a Fast Food meal on the exercise induced adipokine changes? A randomized cross-over clinical trial

• Tipo: Artigo em Revista Científica Internacional
• Data: 2019

Autores

Diana Silva (Autor) Outra; Rita Moreira (Autor) Outra; Marília Beltrao (Autor) Outra; Oksana Sokhatska (Autor) Outra; Tiago Montanha (Autor) Outra; Andreia Pizarro (Autor) FADEUP; Vanessa Garcia-Larsen (Autor) Outra; Rodrigo Villegas (Autor) Outra; Luís Delgado (Autor) Outra; Pedro Moreira (Autor) FCNAUP; Joana Carvalho (Autor) FADEUP; André Moreira (Autor) FMUP

Revista

Título: PLoS ONE

Vol. 14 Nº 4

Páginas: e0215475/1-0215475/15

ISSN: 1932-6203

Editora: Public Library of Science

Indexação

ISI Web of Knowledge - 4 Citações

Scopus - 4 Citações

Classificação Científica

FOS: Ciências sociais

Outras Informações

ID Authenticus: P-00Q-GBK

DOI: 10.1371/journal.pone.0215475

Abstract (EN): Background Adipose tissue-derived adipokines are pro-inflammatory cytokines involved in metabolic-related diseases and can be influenced by diet and exercise. We aimed to compare the effect of a Mediterranean (MdM) compared with Fast Food (FFM) meal on the exercise induced adipokines changes. Methods In a double blinded cross over trial, 46 participants were randomly assigned to one of two standardized iso-energy pre-exercise meals: FFM or MdM-type. Three hours after each meal, participants completed a treadmill exercise test (EC). Serum adiponectin, resistin, PAI-1, lipocalin-2/NGAL and adipsin were determined by Luminex magnetic bead immunoassay. Wilcoxon signed rank test compared changes before/after meal and before/after EC and a linear mixed model evaluated the effect of meals on the adipokine response to exercise, adjusted for confounders. Results Thirty-nine participants (mean age of 25, with a standard deviation of 5 years) completed the trial (56% females). For both interventions, a significant reduction of adipsin after each meal and a significant increase of lipocalin, PAI-1, adipsin and resistin, after exercise was observed. When exercise was preceded by a MdM meal a higher increase in adipsin levels was seen. Conclusion Acute exercise induced an increase of circulatory levels of adipsin, resistin, lipocalin and PAI-1, but not adiponectin. A pre-exercise Mediterranean meal potentiated the increase of adipsin after the exercise test, which possibly relates to the immune regulatory role of adipsin. These changes suggest a cross-talk between the immune and metabolic immediate response to exercise and its modulation by the pre-exercise diet composition.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 15