Go to:
Logótipo
Comuta visibilidade da coluna esquerda
Logótipo
Você está em: Start > Publications > View > Effects of pH on salicylic acid toxicity in terms of biomarkers determined in the marine gastropod Gibbula umbilicalis
Publication

Effects of pH on salicylic acid toxicity in terms of biomarkers determined in the marine gastropod Gibbula umbilicalis

Title
Effects of pH on salicylic acid toxicity in terms of biomarkers determined in the marine gastropod Gibbula umbilicalis
Type
Article in International Scientific Journal
Year
2020
Authors
Dionisio, R
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Daniel, D
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Arenas, F
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Campos, JC
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Paulo Costa
(Author)
FFUP
View Personal Page You do not have permissions to view the institutional email. Search for Participant Publications View Authenticus page View ORCID page
Nunes, B
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Correia, AT
(Author)
Other
The person does not belong to the institution. The person does not belong to the institution. The person does not belong to the institution. Without AUTHENTICUS Without ORCID
Journal
Vol. 158
ISSN: 0141-1136
Publisher: Elsevier
Other information
Authenticus ID: P-00S-1K6
Abstract (EN): Alterations of the physical-chemical properties of the oceans due to anthropogenic activities are, at present, one of the most concerning environmental issues studied by researchers. One of these issues is ocean acidification, mainly caused by overproduction and release of carbon dioxide (CO2) from anthropogenic sources. Another component of environmental degradation is related to the production and release of potential toxic compounds, namely active pharmaceutical ingredients, into the aquatic environment that, combined with oceanic acidification, can cause unpredictable and never before considered deleterious effects on non-target marine organisms. Regarding this issue, the hereby study used predictions of future ocean acidification to simulate realistic scenarios of environmental exposure to a common therapeutic drug, salicylic acid (SA), in the marine gastropod Gibbula umbilicalis under different pH values. This species was exposed to a range of pH values (8.2, 7.9 and 7.6), and to already reported environmentally realistic concentrations (5, 25 and 125 mu g/L) of SA. To evaluate the effects of these environmental stressors, key physiological biomarkers (GSTs, CAT, TBARS, AChE and COX) and shell hardness (SH) were quantified. Results from the present study showed that CAT and GSTs activities were enhanced by SA under water acidification; increased lipid peroxidation was also observed in organisms exposed to SA in more acidic media. In addition, the hereby study demonstrated the neurotoxic effects of SA through the inhibition of AChE. Effects were also observed in terms of COX activity, showing that SA absorption may be affected by water acidification. In terms of SH, the obtained data suggest that SA may alter the physical integrity of shells of exposed organisms. It is possible to conclude that the combination of seawater acidification and exposure to toxic xenobiotics (namely to the drug SA) may be strenuous to marine communities, making aquatic biota more susceptible to xenobiotics, and consequently endangering marine life in an unpredictable extent.
Language: English
Type (Professor's evaluation): Scientific
No. of pages: 10
Documents
We could not find any documents associated to the publication.
Related Publications

Of the same journal

The use of Hediste diversicolor in the study of emerging contaminants (2020)
Another Publication in an International Scientific Journal
Silva, MSS; Pires, A; Almeida, M; Oliveira, M
ChoDinesterase enzymes: Appraisal of inhibitory mechanisms for their use as an environmental biomarker of toxicity (2008)
Other Publications
frasco, mf; carvalho, f; guilhermino, l; stojan, j; fournier, d
Variability of metal contents in the sea rush Juncus maritimus - estuarine sediment system through one year of plant's life (2006)
Article in International Scientific Journal
Marisa M R Almeida; Mucha, AP; Vasconcelos, MTSD
Urogenital papilla feminization in male Pomatoschistus minutus from two estuaries in northwestern Iberian Peninsula (2006)
Article in International Scientific Journal
Rodrigues, P; reis-henriques, ma; Campos, J; Santos, MM
Urban vs. extra-urban environments: Scales of variation of intertidal benthic assemblages in north Portugal (2014)
Article in International Scientific Journal
Oliveira, JP; Sousa Pinto, I; Weber, GM; Bertocci, I

See all (27)

Recommend this page Top
Copyright 1996-2024 © Faculdade de Psicologia e de Ciências da Educação da Universidade do Porto  I Terms and Conditions  I Acessibility  I Index A-Z  I Guest Book
Page created on: 2024-10-10 at 13:16:09 | Acceptable Use Policy | Data Protection Policy | Complaint Portal