Metaplasia - A transdifferentiation process that facilitates cancer development: The model of gastric intestinal metaplasia

• Type: Another Publication in an International Scientific Journal
• Date: 2006

Authors

Mesquita, P (Author) Other; Raquel Almeida (Author) FMUP; Lunet N (Author) FMUP; Celso Reis (Author) FMUP; Santos-Silva F (Author) FMUP; Serpa, J (Author) Other; Van Seuningen, I (Author) Other; Barros H (Author) FMUP; David L (Author) FMUP

Journal

Title: Critical Reviews in Oncogenesis

Vol. 12

Pages: 3-26

ISSN: 0893-9675

Publisher: Begell House

Indexing

Scopus - 39 Citations

Other information

Authenticus ID: P-007-GB1

DOI: 10.1615/critrevoncog.v12.i1-2.20

Abstract (EN): Metaplasia, in general, and intestinal metaplasia, in particular, are transdifferentiation processes triggered by environmental aggressions. The heterogeneity of different morphologic variants of metaplasia and distinction from close morphologic entities - heterotopia and hamartoma - is reviewed. Recent data on the characterization of the molecular and epidemiological data involved in the development and progression of lesions of gastric intestinal metaplasia are discussed. A redefinition of intestinal metaplasia is proposed. © 2006 by Begell House, Inc.

Language: English

Type (Professor's evaluation): Scientific