Oral Biosciences I

Code:

1051

Acronym:

BIOI

Keywords
Classification	Keyword
OFICIAL	Biology

Instance: 2016/2017 - 1S

Active?	Yes
Responsible unit:	3.º Ciclo Doutoramentos
Course/CS Responsible:	Dental Medicine

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
DMDB	0	Dental Medicine PhD - Study Plan 2009/2010	1	-	3	28	81

Teaching language

Portuguese

Objectives

The syllabus of the course allows students to gain a global perspective of the main cellular and molecular characteristics of the oral cavity, under physiological conditions and in pathological conditions. It is valued the importance of biochemical and molecular knowledge associated with various pathological changes in different structures of the oral cavity, to allow a better understanding of them, as well as a greater ability to act in clinical practice is valued. It also seeks to encourage scientific research among students in order to highlight the need for constant updating of knowledge as an asset for the performance of the dentist profession.

Learning outcomes and competences

Acquisition of knowledge related to the cellular and molecular characteristics of the oral cavity. Development of theoretical skills on the biochemical mechanisms associated with some physiological and pathological changes of the oral cavity.

Understanding of the molecular events involved in the aging of the oral cavity.

Integration of knowledge of biology and oral biochemistry in the areas of clinical intervention of dental medicine.

Working method

Presencial

Program

Cell biology of the oral cavity: main cell types.

Cellular communications in the oral cavity: cellcell contacts, paracrinic communications and exosomes. Biochemistry of saliva.

Molecular mechanisms of saliva production.

Biochemical basis of some disease of the oral cavity: xerostomia, halitosis, oral cancer, dental fluorosis and dentinogenesis imperfecta.

Dental aging. Salivary aging.

Mandatory literature

Bollen CM, Beikler T; Halitosis: the multidisciplinary approach, Int J Oral Sci. 4:55-63., 2012
Seow WK; Developmental defects of enamel and dentine: challenges for basic science research and clinical management, Aust Dent J. 59 Suppl 1:143-54., 2014
Denbesten P, Li W; Chronic fluoride toxicity: dental fluorosis., Monogr Oral Sci. 22:81-96., 2011
Montero PH, Patel SG; Cancer of the oral cavity., Surg Oncol Clin N Am. 24:491-508., 2015
Rajwar YC, Jain N, Bhatia G, Sikka N, Garg B, Walia E; Expression and Significance of Cadherins and Its Subtypes in Development and Progression of Oral Cancers: A Review, J Clin Diagn Res. 9:ZE05-7, 2015
Abrams AP, Thompson LA; Physiology of aging of older adults: systemic and oral health considerations., Dent Clin North Am. 58:729-38., 2014
Thomson WM, Ma S; An ageing population poses dental challenges., Singapore Dent J. 35C:38, 2014
Mandel L; Salivary gland disorders., Med Clin North Am. 98:1407-49., 2014

Teaching methods and learning activities

Interactive and participated lectures, with analysis of scientific papers and discussion of some clinical cases. Preparation of a written work on a topic related to the syllabus of the course.

Distributed evaluation without final exam. Students will have to make a written work, where they should apply and develop contents related to the study plan.

Evaluation Type

Distributed evaluation without final exam

Assessment Components

Designation	Weight (%)
Trabalho escrito	100,00
Total:	100,00

Calculation formula of final grade

Students will have to make a written work, where they should apply and develop contents related to the study plan.
The final work will be evaluated and the assigned rating will correspond to the final grade in the course.

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