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Project/Service Agreement:Referência: PTDC/QUI-BIQ/102827/2008

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Status
Projeto EncerradoClosed
Publication
PublicadoPublished
General Data
Code: 64253
 
Reference: Referência: PTDC/QUI-BIQ/102827/2008
Short name: Referência: PTDC/QUI-BIQ/102827/2008
Title: Design and Biological Activity of Fluorinated Peptides on the Amyloid Beta-Peptide Aggregation
Competitive Funding: Yes
Does it involve businesses?:
No. of Participating Institutions: 1
Scope
Type: Funded Project
 
Geographical Scope: National
 
Type of Action: R&TD
Funding
Programme: I&DT - Projectos de I&DT em Todos os Domínios Científicos
Funding Institution: FCT - Fundação para a Ciência e a Tecnologia
Financial Geographical Scope: National
Scheduling
Effective Start Date: 2010-06-01
Expected Completion Date: 2013-05-31
Effective Completion Date: 2013-11-30
Budget
Currency: EUR
 
Total Approved Budget: 116.784,00 EUR
Details
Summary: Concepção de péptidos fluorados para inibição da agregação do péptido beta-amilóide e avaliação da sua actividade biológica
URL: https://www.fct.pt/apoios/projectos/consulta/vglobal_projecto?idProjecto=102827&idElemConcurso=2700
Scientific Context
Scientific Domain (FOS - Level 2): Engineering and technology > Other engineering and technologies

Academic fields (CORDIS - Level 5)

Mais informações There are no Academic Fields associated with the Project.

Keywords

  • Alterações conformacionais
  • Inibição da toxicidade do amilóide
  • Péptido beta-amilóide
  • Péptidos fluorados bioactivos
Documents
Mais informações There are no Documents associated with the Project.

Publications associated with the Project

Interaction Studies Between Amyloid Beta-Peptides and Biocompatible Polymers
International Conference Proceedings Book
A. M. Saraiva (Author) (FEUP); S. Rocha (Author) (FEUP); A.F. Thümann (Author) (Other); M. Pereira (Author) (FEUP); M. A. N. Coelho (Author) (FEUP); G. Brezesinski (Author) (Other); H. Möhwald (Author) (Other)
2007
Interaction studies of amyloid-ß peptide with ionic fluorinated amphiphiles
Article in International Conference Proceedings Book
Joana Loureiro (Author) (FEUP); Manuel Coelho (Author) (FEUP); Sandra Rocha (Author) (FEUP); Maria do Carmo Pereira (Author) (FEUP)
2013
Immunoliposomes for Alzheimer's Disease Therapy
Article in International Conference Proceedings Book
Joana A. Loureiro (Author) (FEUP); Bárbara Gomes (Author) (FEUP); Manuel Neto Coelho (Author) (FEUP); Maria Do Carmo Pereira (Author) (FEUP); Sandra Rocha (Author) (FEUP)
2013
The effect of a fluorinated cholesterol derivative on the stability and physical properties of cationic DNA vectors
Article in International Scientific Journal
Diana Paiva (Author) (FEUP); Albertoo Martín-Molina (Author) (Other); Isabel Cardoso (Author) (Other); Manuel Quesada-Pérez (Author) (Other); Maria do Carmo Pereira (Author) (FEUP); Sandra Rocha (Author) (FEUP)
2013
Nanostructure of polysaccharide complexes
Article in International Scientific Journal
Sílvia Coelho (Author) (FEUP); Susana Moreno Flores (Author) (Other); José L. Toca-Herrera (Author) (Other); Manuel A. N. Coelho (Author) (FEUP); M. Carmo Pereira (Author) (FEUP); Sandra Rocha (Author) (Other)
2011
Charged surfactants induce a non-fibrillar aggregation pathway of amyloid-beta peptide
Article in International Scientific Journal
Joana A. Loureiro (Author) (FEUP); Sandra Rocha (Author) (FEUP); Maria do Carmo Pereira (Author) (FEUP)
2013
Targeting nanoparticles across the blood-brain barrier with monoclonal antibodies
Article in International Scientific Journal
J.A. Loureiro (Author) (FEUP); Bárbara Gomes (Author) (FEUP); M. A. N. Coelho (Author) (FEUP); M. do Carmo Pereira (Author) (FEUP); Sandra Rocha (Author) (FEUP)
2014
Alzheimer's disease: Development of a sensitive label-free electrochemical immunosensor for detection of amyloid beta peptide
Article in International Scientific Journal
Pedro Carneiro (Author) (FEUP); Joana Loureiro (Author) (FEUP); Cristina Delerue Matos (Author) (Other); Simone Morais (Author) (Other); Maria do Carmo Pereira (Author) (FEUP)
2017
Fluorinated beta-sheet breaker peptides
Article in International Scientific Journal
Joana A. Loureiro (Author) (FEUP); Rosa Crespo (Author) (FEUP); Hans Börner (Author) (Other); Pedro M. Martins (Author) (ICBAS); Fernando A. Rocha (Author) (FEUP); Manuel Coelho (Author) (FEUP); M. Carmo Pereira (Author) (FEUP); Sandra Rocha (Author) (Other)
2014
Synthesis and study of the complex formation of a cationic alkyl-chain bola amino alcohol with DNA: in vitro transfection efficiency
Article in International Scientific Journal
Maria do Carmo Pereira (Author) (FEUP); Diana Paiva (Author) (FEUP); Thomas Markowski (Author) (Other); Bodo Dobner (Author) (Other); Gerald Brezesinski (Author) (Other); Helmuth Möhwald (Author) (Other); Sandra Rocha (Author) (FEUP)
2015
Chitosan conjugates for DNA delivery
Article in International Scientific Journal
Diana Paiva (Author) (FEUP); Galya Ivanova (Author) (Other); Maria do Carmo Pereira (Author) (FEUP); Sandra Rocha (Author) (FEUP)
2013
Langmuir monolayers of monocationic lipid mixed with cholesterol or fluorocholesterol: DNA adsorption studies
Article in International Scientific Journal
Diana Paiva (Author) (FEUP); Gerald Brezesinski (Author) (Other); Maria do Carmo Pereira (Author) (FEUP); Sandra Rocha (Author) (FEUP)
2013
Peptide-surfactant interactions: Consequences for the amyloid-beta structure
Article in International Scientific Journal
Sandra Rocha (Author) (FEUP); Joana A. Loureiro (Author) (FEUP); Gerald Brezesinski (Author) (Other); Maria do Carmo Pereira (Author) (FEUP)
2012
Institutions Participating in the Project
Institution Contact Create Tab?
Name Short name Country Type Participation Name Telephone Email
Faculdade de Engenharia da Universidade do Porto FEUP Portugal University Proponent Maria Do Carmo Pereira mcsp@fe.up.pt
 
Budgets and Teams
Approved Budget: 116.784,00 EUR
Approved Funded Amount: 116.784,00 EUR
Approved co-funded Amount: 0,00 EUR
Funding Rate: 100 %
Confidential Budget:

People in the Project

Institution Name Short name Role Dedication (%) Contribution (%) Allocation
Start date End date
FEUP Joana Angélica de Sousa Loureiro JASL Grant recipient 100 2010-09-15 2013-10-14
FEUP Manuel Álvaro Neto Coelho MANC Researcher 10 20
FEUP Maria do Carmo da Silva Pereira MCP Official Researcher at the OU 30 80

Technicians in the Project

Technician Contact
FEUP 242136 Ana Paula Ferreira da Conceição
Laboratories
Mais informações There are no Laboratories associated with the Project.
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