Biochemistry

Code:

103

Acronym:

103

Instance: 2005/2006 - A

Active?	Yes
Web Page:	http://www.fmd.up.pt/labcell
Course/CS Responsible:

Cycles of Study/Courses

Acronym	No. of Students	Study Plan	Curricular Years	Credits UCN	Credits ECTS	Contact hours	Total Time
MD	111	Plano oficial a partir de 2000	1	8	12	-
		Plano oficial a partir de 2005	1	8	12	-

Objectives

"Biochemistry" - complete understanding, at the molecular level, of the chemical processes associated with living cells - aims at:
. Knowledge of the structure and function of the biomelecules
. Study of the main metabolic pathways of the carbohydrates, lipids, proteins and nucleic acids, and their regulatory mechanisms
. Integration of the metabolism
. Characterization of the mechanisms of transmission of genetic information
. Understanding of the biochemistry basis of representative physiopathological processes
. Aquisition of skils in laboratorial work and tretment of results

Program

PROGRAM:

Part I - Introduction to biological processes
Organic and inorganic biomolecules
The water
Bioenergetics and metabolism
Kinetics of enzyme reactions

Part II - Organic biomolecules: structure, function and metabolism
Carbohydrates
Lipids
Proteins
Nucleic acids

Part III - Storage and transmission of the genetic information
Transcription
transduction
Application of genetic technology

Main Bibliography

“Lehninger Principles of Biochemistry”, 4ª edition. D.L. Nelson, M.M. Cox. Freeman, 2005

“Harper’s Ilustrated Biochemistry”, 26ª edition. R.K. Murray, D.K. Granner, P.A. Mayes, V.W. Rodwell. Lange/McGraw-Hill, 2003.

“Textbook of Biochemistry with Clinical Correlations”, 5ª edition. T.M. Devlin. Wiley-Liss, 2002.

“Biochemistry”, 5ª edition. J.M. Berg, J.L. Tymoczko, L. Stryer. Freeman, 2002.

Complementary Bibliography

Manual das Aulas Práticas – João Rodrigues – FMDUP

“Medical Biochemistry”, 2nd edition, Baynes JW, Dominiczak MH, Elsevier Mosby, 2005.

“Bioquímica para o clínico”. Borel J-P, Maquart F-X, Gillery P, Exposito M. Instituto Piaget, 1999.

Teaching methods and learning activities

. Theoretical sessions: 2 sessions of 60 minutes per week.
. Theoretical-practical sessions: 1 session of 120 minutes per week.
. Practical sessions:
Lab sessions - 1 session of 120 minutes every two weeks.
Biochemistry of the physiopathological processes - 1 session of 120 minutes every two weeks.

Evaluation Type

Distributed evaluation with final exam

Eligibility for exams

Attendance of at least 2/3 of the theoretical-practical and practical sessions.

Minimum classification of the continuous assessment to attend the written exam = 2 points (maximum = 4 points)

Calculation formula of final grade

Option 1:
Arithmetic mean of the classifications of the two mid-term tests + classification of the continuous evaluation + classification of the monography.

Option 2:
Classification of the final test + classification of the continuous evaluation + classification of the monography.

Minimum final classification of approval = 10 points (out of 20)

Classification improvement

General rules established by the Pedagogic Council of the Faculty.

Observations

Teaching staff:
Maria Helena Raposo Fernandes
João Rodrigues
Pedro de Sousa Gomes