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2023
  • Unveiling the angiogenic effects of cannabinoids: Enhancers or inhibitors?
    Maia J, Fonseca BM, Teixeira N, Correia-da-Silva G
    Biochemical Pharmacology, 215:115686. 2023
    Doi: 10.1016/j.bcp.2023.115686

  • Effects of a combination of cannabidiol and delta-9-tetrahydrocannabinol on key biological functions of HTR-8/SVneo extravillous trophoblast cells
    Alves P, Amaral C, Teixeira N, Correia-da-Silva G
    Toxicology, 495: 153614
    Doi: 10.1016/j.tox.2023.153614

  • Bile acids profile and redox status in healthy infants.
    Santos-Silva E, Rocha S, Ramos RC, Coutinho H, Catarino C, Teixeira F, Henriques G, Lopes AI, Santos-Silva A, Brites D.
    Pediatric Research, 93(7):1856-1864. 2023
    Doi: 10.1038/s41390-022-02350-y

  • TNFR2 as a Potential Biomarker for Early Detection and Progression of CKD.
    Lousa I, Reis F, Viana S, Vieira P, Vala H, Belo L, Santos-Silva A.
    Biomolecules, 13(3): 534. 2023
    Doi: 10.3390/biom13030534.

  • Polysulfone membranes doped with neutrophil elastase inhibitors.
    Rocha S, Félix R, Valente MJ, Bento-Silva A, Rebelo R, Amorim CG, Araújo AN, Moreira R, Santos-Silva A, Montenegro C BSM.
    Membranes, 13(1): 89. 2023
    Doi.org/10.3390/membranes13010089

  • The association of leptin with left ventricular hypertrophy in end-stage kidney disease patients on dialysis.
    Coimbra S, Catarino C, Faria MS, Nunes JPL, Rocha S, Valente MJ, Rocha-Pereira P, Bronze-da-Rocha E, Bettencourt N, Beco A, Marques SHM, Oliveira JG, Madureira J, Fernandes JC, Miranda V, Belo L, Santos-Silva A.
    Biomedicines, 11 (4): 1026. 2023
    Doi: 10.3390/biomedicines11041026

  • Inhibition of erythrocyte's catalase, glutathione peroxidase or peroxiredoxin 2 - Impact on cytosol and membrane.
    Melo D, Coimbra S, Rocha S, Santos-Silva A.
    Archive Biochemistry Biophysics, 739:109569. 2023
    Doi: 10.1016/j.abb.2023.109569

  • Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021.
    Ong KL, Stafford LK, McLaughlin SA, Boyko EJ, Vollset SE, Smith AE, Dalton BE, Belo L, Zou Z, Zumla A, Zuniga YMH, Magliano DJ, Murray CJL, Hay SI, Vos T.
    Lancet,402(10397):203-234. 2023
    Doi: 10.1016/S0140-6736(23)01301-6

  • Mitochondria Quality Control and Male Fertility.
    Costa J, Braga P, Rebelo I, Oliveira PF, Alves MG.
    BIOLOGY, 12(6):827-848. 2023
    Doi: 10.3390/biology12060827

  • Retinoic acid (all-trans) presents antioxidant properties within human ovary and reduces progesterone production by human granulosa cells.
    Fonseca BM, Cruz R, Pinto B, Costa L, Felgueira E, Oliveira P, Casal S, Rebelo I.
    Syst Biol Reprod Med, 69(2):129-141. 2023
    Doi: 10.1080/19396368.2022.2120439

  • Nanoparticles as a Delivery System of Antigens for the Development of an Effective Vaccine against Toxoplasma gondii.
    Brito C, Lourenço C, Magalhães J, Reis S, Borges M.
    Vaccines, 11(4):733-746. 2023
    Doi: 10.3390/vaccines11040733

  • The effects of delta-9-tetrahydrocannabinol administration in the regulation of female rat sociosexual behaviour.
    Costa FM, Fonseca BM, Sá SI.
    Eur J Neurosci, Apr;57(7):1068-1080, 2023
    Doi: 10.1111/ejn.15939

  • The endocannabinoidome in human placenta: Possible contribution to the pathogenesis of preeclampsia.
    Maia J, Iannotti FA, Piscitelli F, Fonseca BM, Braga A, Braga J, Teixeira N, Di Marzo V, Correia-da-Silva G.
    Biofactors, 1-13. 2023
    Doi: 10.1002/biof.1952

  • Long-Term Tamoxifen Effects in the Cyclic Interaction of the Endocannabinoid and Endocrine System in the Rat Central Nervous System.
    Fonseca BM, Bhowmick N, Cunha S, Maia J, Correia-da-Silva G, Teixeira N, Sá SI.
    Biomedicines, 11(3):720. 2023
    Doi: 10.3390/biomedicines11030720

  • An Exemestane Derivative, Oxymestane-D1, as a New Multi-Target Steroidal Aromatase Inhibitor for Estrogen Receptor-Positive (ER+) Breast Cancer: Effects on Sensitive and Resistant Cell Lines.
    Amara Cl, Correia-da-Silva G, Almeida CF, Valente MJ, Varela C, Tavares-da-Silva E, Vinggaard AM, Teixeira N, Roleira FMF.
    Molecules, 28:789-809. 2023
    Doi: 10.3390/ molecules28020789

  • Anti-cancer properties of hydroethanolic extracts of Juniperus oxycedrus L. in breast cancer cells.
    El-Abid H, Amaral C, Cunha SC, Correia-da-Silva G, Fernandes JO, Moumni M, Teixeira N.
    Journal of Herbal Medicine, 37: 100614-100625. 2023
    Doi: 10.1016/j.hermed.2022.100614

  • Cannabidiol as a Promising Adjuvant Therapy for Estrogen Receptor-Positive Breast Tumors: Unveiling Its Benefits with Aromatase Inhibitors.
    Almeida CF, Teixeira N, Valente MJ, Vinggaard AM, Correia-da-Silva G, Amaral C.
    Cancers, 15:2517-2539. 2023
    Doi: 10.3390/ cancers15092517

  • Design, synthesis, biological activity evaluation and structure-activity relationships of new steroidal aromatase inhibitors. The case of C-ring and 7β substituted steroids.
    Roleira FMF, Costa SC, Gomes AR, Varela CL, Amaral C, Augusto TV, Correia-da-Silva G, Romeo I, Costa G, Alcaro S, Teixeira N, Tavares-da-Silva EJ.
    Bioorganic Chemistry, 131:106286-106297. 2023
    Doi: 10.1016/j.bioorg.2022.106286

  • In Vitro Effects of Combining Genistein with Aromatase Inhibitors: Concerns Regarding Its Consumption during Breast Cancer Treatment.
    Bezerra PHA, Amaral C, Almeida CF, Correia-da-Silva G, Torqueti MR, Teixeira N.
    Molecules, 28:4893-4906. 2023
    Doi: 10.3390/molecules28134893

  • Changing the paradigm in health and care services: modern value chains using open innovation for the creation of new digital health solutions.
    Carrilho J, Videira D, Campos C, Midão L, Costa E.
    Front Digit Health, 5:1216357. 2023
    Doi: 10.3389/fdgth.2023.1216357

  • Patient-centred digital biomarkers for allergic respiratory diseases and asthma: the ARIA-EAACI approach.
    Bousquet J, Shamji MH, Anto JM, Schünemann HJ, Costa E, Ollet M.
    Allergy, 78(7):1758-1776. 2023
    Doi:10.1111/all.15740

  • Translation and cross-cultural adaptation of the ABC taxonomy for medication adherence into Portuguese – Updating patients into people.
    Bernardo C, Tosin MHS, Almada M, Sampaio R, Oliveira BGR, Costa E, Vrijens B, Costa FC.
    Research in Social and Administrative Pharmacy, 19(4):653-659. 2023
    Doi: 10.1016/j.sapharm.2022.12.010

  • Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air® approach.
    Bousquet J, Anto JM, Sousa-Pinto B, Czarlewski W, Bedbrook A, Haahtela T, Costa E, et. al.
    Clinical and Translational Allergy, 13(1):e12215. 2023
    Doi: 10.1002/clt2.12215

  • Unsupervised algorithms to identify potential under-coding of secondary diagnoses in hospitalisations databases in Portugal.
    Portela D, Amaral R, Rodrigues PP, Freitas A, Costa E, Fonseca JA, Sousa-Pinto B.
    Health Information Management Journal 1-9. 2023
    Doi: 10.1177/18333583221144663

  • Impact of multimorbidity patterns in hospital admissions: the case study of asthma.
    Portela D, Pereira Rodrigues P, Freitas A, Costa E, Bousquet J, Fonseca JA, Sousa-Pinto B.
    Journal of Asthma, 1-11. 2023
    Doi: 10.1080/02770903.2023.2185154

  • Cutoff values of MASK-air Patient-Reported Outcome Measures.
    Sousa-Pinto B, Sá-Sousa A, Vieira RJ, Amaral R, Pereira AM, Anto JM, Costa E, et. al.
    Journal of Allergy and Clinical Immunology: In Practice, 11(4):1281-1289.e5. 2023
    Doi: 10.1016/j.jaip.2022.12.005

  • Una profesión, una (bio)ética. Una visión conceptual
    Marques F.
    Anales de la Real Academia de Farmacia, 89 (2):177-190. 2023
    Doi: 10.53519/analesranf





2022
  • New Insights into Adiponectin and Leptin Roles in Chronic Kidney Disease.
    Coimbra S, Rocha S, Valente MJ, Catarino C, Bronze-da-Rocha E, Belo L, Santos-Silva A.
    Biomedicines, 10:2642. 2022
    Doi: 10.3390/biomedicines10102642

  • Population-level risks of alcohol consumption by amount, geography, age, sex, and year: a systematic analysis for the Global Burden of Disease Study 2020.
    Bryazka D, Reitsma MB, Griswold MG, Abate KH, Belo L, Zhong C, Zmaili M, Zuniga YMH, Gakidou E.
    Lancet, 400 (10347): p. 185-235. 2022
    Doi: 10.1016/S0140-6736(22)00847-9

  • The signaling pathway of TNF receptors: linking animal models of renal disease to human CKD.
    Lousa I, Reis F, Santos-Silva A, Belo L.
    International Journal of Molecular Sciences, 23: 3284. 2022
    Doi: 10.3390/ijms23063284

  • Real-world data using mHealth apps in rhinitis, rhinosinusitis and their multimorbidities.
    Sousa-Pinto B, Anto A, Berger M, Costa E, Bousquet J.
    Clin Transl Allergy, 12(11):e12208. 2022
    Doi: 10.1002/clt2.12208

  • Establishing the criterion validity of self-report measures of adherence in hemodialysis through associations with clinical biomarkers: A systematic review and meta-analysis.
    Sousa H, Ribeiro O, Costa E, Christensen AJ, Figueiredo D.
    PLoS One, 17(10):e0276163. 2022
    Doi: 10.1371/journal.pone.0276163

  • Management of allergic rhinitis symptoms in the pharmacy Pocket guide 2022.
    Lourenço O, Cvetkovski B, Kritikos V, House R, Scheire S, Costa E, Fonseca JA, Menditto E, Bedbrook A, Bialek S, Briedis V, Boussery K, Canonica GW, Haahtela T, Kuna P, Mullol J, Orlando V, Samolinski B, Wallace D, Duggan C, Paulino E, Pinto GS, Söderlund LÅ, Bousquet J, Bosnic-Anticevich S.
    Clin Transl Allergy, 2022
    Doi: 10.1002/clt2.12183

  • The Allergic Rhinitis and Its Impact on Asthma (ARIA) Approach of Value-Added Medicines: As-Needed Treatment in Allergic Rhinitis.
    Bousquet J, Toumi M, Sousa-Pinto B, Costa E, Zuberbier T.
    J Allergy Clin Immunol, 10(11):2878-2888. 2022
    Doi: 10.1016/j.jaip.2022.07.020

  • Comparison of rhinitis treatments using MASK-air® data and considering the minimal important difference.
    Sousa-Pinto B, Schünemann HJ, Sá-Sousa A, Costa E, Bousquet J.
    Allergy, 77(10):3002-3014. 2022
    Doi: 10.1111/all.15371

  • Allergen immunotherapy in MASK-air users in real-life: Results of a Bayesian mixed-effects model.
    Sousa-Pinto B, Azevedo LF, Sá-Sousa A, Costa E, Pfaar O.
    Clin Transl Allergy, 12(3):e12128. 2022
    Doi: 10.1002/clt2.12128

  • Behavioural patterns in allergic rhinitis medication in Europe: A study using MASK-air® real-world data.
    Sousa-Pinto B, Sá-Sousa A, Vieira RJ, Costa E, Bousquet J.
    Allergy, 77(9):2699-2711. 2022
    Doi: 10.1111/all.15275

  • Applying the FAIR4Health Solution to Identify Multimorbidity Patterns and Their Association with Mortality through a Frequent Pattern Growth Association Algorithm.
    Carmona-Pírez J, Poblador-Plou B, Poncel-Falcó A, Rochat J, Alvarez-Romero C, Martínez-García A, Angioletti C, Almada M, Gencturk M, Sinaci AA, Ternero-Vega JE, Gaudet-Blavignac C, Lovis C, Liperoti R, Costa E, Parra-Calderón CL, Moreno-Juste A, Gimeno-Miguel A, Prados-Torres A.
    Int J Environ Res Public Health, 19(4):2040. 2022
    Doi: 10.3390/ijerph19042040

  • Pharmacological Adherence Behavior Changes during COVID-19 Outbreak in a Portugal Patient Cohort.
    Midão L, Almada M, Carrilho J, Sampaio R, Costa E.
    Int J Environ Res Public Health, 19(3):1135. 2022
    Doi: 10.3390/ijerph19031135

  • Hematological changes in SARS-COV-2 positive patients.
    Urbano M, Costa E, Geraldes C.
    Hematol Transfus Cell Ther, 44(2):218-224. 2022
    Doi: 10.1016/j.htct.2021.12.001

  • Development and validation of combined symptom-medication scores for allergic rhinitis.
    Sousa-Pinto B, Azevedo LF, Jutel M, Costa E, Bousquet J.
    Allergy, 77(7):2147-2162. 2022
    Doi: 10.1111/all.15199

  • Caring for patients with end-stage renal disease during COVID-19 lockdown: What (additional) challenges to family caregivers?
    Sousa H, Frontini R, Ribeiro O, Paúl C, Costa E, Amado L, Miranda V, Ribeiro F, Figueiredo D.
    Scand J Caring Sci, 36(1):215-224. 2022
    Doi: 10.1111/scs.12980

  • FAIR4Health: Findable, Accessible, Interoperable and Reusable data to foster Health Research.
    Alvarez-Romero C, Martínez-García A, Sinaci A, Gencturk M, Méndez E, Hernández-Pérez T, Liperoti R, Angioletti C, Löbe M, Ganapathy N, Deserno T, Almada M, Costa E… Ashley K, Horton L, Parra Calderón C.
    Open Research Europe, 2:34. 2022
    Doi: 10.12688/openreseurope.14349.2

  • Pharmacological and Non-Pharmacological Agents versus Bovine Colostrum Supplementation for the Management of Bone Health Using an Osteoporosis-Induced Rat Model.
    Kydonaki EK, Freitas L, Reguengo H, Raposo-Simón C, Bastos AR, Fernandes EM, Canadas RF, Oliveira JM, Correlo VM, Reis RL, Vliora M, Gkiata P, Koutedakis Y, Ntina G, Pinto R, Carrillo AE, Marques F, Amorim T.
    Nutrients, 14(14), 2837. 2022
    Doi:10.3390/nu14142837

  • Pd(2)Spermine Complex Shows Cancer Selectivity and Efficacy to Inhibit Growth of Triple-Negative Breast Tumors in Mice.
    Vojtek, M, Goncalves-Monteiro S, Seminska P, Valova K, Bellon L, Dias-Pereira,P, Marques F, Marques M, Batista-de-Carvalho A, Mota-Filipe H, Ferreira I, Diniz C.
    Biomedicines, 10 (2): 210 (20). 2022
    Doi: 10.3390/biomedicines10020210

  • Effects of chronic tamoxifen treatment in female rat sexual behavior.
    Pinto CA, Fonseca BM, Sá SI.
    Heliyon, 8(12):e12362. 2022
    Doi: 10.1016/j.heliyon.2022.e12362

  • Increased expression of NLRP3 inflammasome components in granulosa cells and follicular fluid interleukin(IL)-1beta and IL-18 levels in fresh IVF/ICSI cycles in women with endometriosis.
    Fonseca BM, Pinto B, Costa L, Felgueira E, Rebelo I.
    Journal of Assisted Reproduction and Genetics, 40(1):191-199. 2022
    Doi: 10.1007/s10815-022-02662-2

  • Unhealthy diets induce distinct and regional effects on intestinal inflammatory signalling pathways and long-lasting metabolic dysfunction in rats.
    Nogueira S, Barbosa J, Faria J, Sá SI, Cardoso A, Soares R, Fonseca BM, Leal S.
    International Journal of Molecular Sciences, 23:18. 2022
    Doi: 10.3390/ijms231810984

  • The role of macrophages phenotypes in the activation of resolution pathways within human granulosa cells.
    Martins TS, Fonseca BM, Rebelo I.
    Reproductive Biology Endocrinology, 20: 116. 2022
    Doi: 10.1186/s12958-022-00983-6

  • Bisphenols A, F, S and AF trigger apoptosis and/or endoplasmic reticulum stress in human endometrial stromal cells.
    Ferreira R., Amaral C, Correia-da-Silva G, Almada M, Borges M, Cunha SC, Fernandes JO, Teixeira N.
    Toxicology, 478: 153282. 2022
    Doi: https://doi.org/10.1016/j.tox.2022.153282

  • Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases Study 2019.
    Armocida B, Monasta L, Sawyer S, Bustreo F, Segafredo G, Castelpietra G, Ronfani L, Pasovic M, Hay S, Belo L, Perel P, Beran D.
    Lancet Child Adolesc Health, 6(6): p. 367-383. 2022
    Doi:10.1016/s2352-4642(22)00073-6

  • Cellular and molecular pathways underlying the nephrotoxicity of gadolinium.
    Reis-Sousa N, Rocha S, Santos-Silva A, Coimbra S, Valente MJ.
    Toxicological Sciences, 186 (1): p. 134-148. 2022
    Doi: 10.1093/toxsci/kfab148

  • The signaling pathway of TNF receptors: linking animal models of renal disease to human CKD.
    Lousa I, Reis F, Santos-Silva A, Belo L.
    International Journal of Molecular Sciences, 23: 3284. 2022
    Doi.org/10.3390/ijms23063284

  • Inflammatory biomarkers in staging of chronic kidney disease: elevated TNFR2 levels accompanies renal function decline.
    Lousa I, Belo L, Valente MJ, Rocha S, Preguiça I, Rocha-Pereira P, Beirão I, Mira F, Alves R, Reis F, Santos -Silva A.
    Inflammation Research, 71 (5-6): p. 591-602. 2022
    Doi: 10.1007/s00011-022-01574-2

  • Cannabinoids in breast cancer: susceptibility for each breast cancer subtype.
    Ferreira-Almeida C, Correia-da-Silva G, Teixeira N, Amaral C.
    Molecules, 27(1): 156. 2022
    Doi: https://doi.org/10.3390/molecules27010156

  • The endocannabinoids anandamide and 2-arachidonoylglycerol modulate the expression of angiogenic factors on HTR8/SVneo placental cells.
    Maia J, Fonseca BM, Teixeira N, Correia-da-Silva G.
    Prostaglandins, Leukotrienes and Essential Fatty Acids, 180: 120440. 2022

  • In Vitro Effects of Mitochondria-Targeted Antioxidants in a Small-Cell Carcinoma of the Ovary of Hypercalcemic Type and in Type 1 and Type 2 Endometrial Cancer.
    Castelôa M, Moreira-Pinto B, Benfeito S, Borges F, Fonseca BM, Rebelo I.
    Biomedicines, 10(4): 800. 2022
    Doi: 10.3390/biomedicines10040800

  • Early unhealthy eating habits underlie morpho-functional changes in the liver and adipose tissue in male rats.
    Nogueira S, Garcez F, Sá S, Moutinho CL, Cardoso A, Soares R, Fonseca BM, Leal S.
    Histochemistry and Cell Biology, 157: p. 657–669. 2022
    doi: 10.1007/s00418-022-02092-2





2021
  • ARIA digital anamorphosis: Digital transformation of health and care in airway diseases from research to practice.
    Bousquet J, Anto JM, Bachert C, Haahtela T, Zuberbier T, Czarlewski W, Bedbrook A, Bosnic-Anticevich S, Canonica GW, Cardona V, Costa E, et. al.
    Allergy, 76(1): p. 168-190 . 2021
    https://doi.org/10.1111/all.14422

  • Allergic rhinitis characterization in community pharmacy customers: a cross-sectional study.
    Guedes H, Morgado M, Rodrigues M, Cruz A, Fonseca C, Costa E, Araujo A.
    Int J Clin Pharm, 43(1): p. 118-127. 2021
    https://doi.org/10.1007/s11096-020-01115-z

  • Being on hemodialysis during the COVID-19 outbreak: A mixed-methods' study exploring the impacts on dialysis adequacy, analytical data, and patients' experiences.
    Sousa H, Ribeiro O, Costa E, Frontini R, Paúl C, Amado L, Miranda V, Ribeiro V, Figueiredo D.
    Semin Dial, 34(1): p. 66-76. 2021
    https://doi.org/10.1111/sdi.12914

  • Bovine Colostrum Supplementation Improves Bone Metabolism in an Osteoporosis-Induced Animal Model.
    Kydonaki EK, Freitas L, Fonseca BM, Reguengo H, Raposo Simón C, Bastos AR, Fernandes EM, Canadas RF, Oliveira JM, Correlo VM, Reis RL, Vliora M, Gkiata P, Koutedakis Y, Ntina G, Pinto R, Carrillo AE, Marques F, Amorim T.
    Nutrients.13(9):2981. PMID: 34578859. 2021
    DOI:10.3390/nu13092981

  • Neuroprotective Bovine Colostrum Attenuates Apoptosis in Dexamethasone-Treated MC3T3-E1 Osteoblastic Cells.
    Martin-Aragon S, Bermejo-Bescós P, Benedí J, Raposo C, Marques F, Kydonaki EK, Gkiata P, Koutedakis Y, Ntina G, Carrillo AE, Amorim T.
    Int J Mol Sci. 22(19):10195. PMID: 34638536. 2021
    DOI:10.3390/ijms221910195

  • Associations between nutrition, energy expenditure and energy availability with bone mass acquisition in dance students: a 3-year longitudinal study.
    Amorim T, Freitas L, Metsios GS, Gomes TN, Wyon M, Flouris AD, Maia J, Marques F, Nogueira L, Adubeiro N, Koutedakis Y.
    Arch Osteoporos.16(1):141. PMID: 34561723. 2021
    doi:10.1007/s11657-021-01005-5

  • Gut Microbiome Composition and Metabolic Status Are Differently Affected by Early Exposure to Unhealthy Diets in a Rat Model.
    Marco P, Henriques A, Azevedo R, Sá S, Cardoso A, Fonseca B, Barbosa J, Leal S.
    Nutrients. 13(9), 3236. 2021
    DOI:10.3390/nu13093236

  • IFNγ and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on Mycobacterium avium-Induced Thymic Atrophy.
    Barreira-Silva P, Melo-Miranda R, Nobrega C, Roque S, Serre-Miranda C, Borges M, Correia-Neves M.
    Front Immunol, 12, 696415. 2021
    doi:10.3389/fimmu.2021.696415

  • Cognitive performance in older adults across Europe based on the SHARE database.
    Barbosa R, Midão L, Almada M, Costa E.
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn, 28(4): p. 584-599. 2021
    https://doi.org/10.1080/13825585.2020.1799927

  • Digital Health Europe (DHE) Twinning on severe asthma-kick-off meeting report.
    Bousquet J, Bedbrook A, Czarlewski W, De Carlo G, Fonseca JA, Ballester MAG, Illario M, Koskinen S, Laatikainen T, Onorato GL, Palkonen S, Patella V, Pham-Thi N, Puggioni F, Ventura MT, Joos G, Kuna P, Louis R, Makris M, Zalud P, Zuberbier T, Bachert C, Brussino L, Carreiro-Martins P, Carrion YRC, Chalubinski M, Costa EM, et al.
    J Thorac Dis, 13(5): p. 3215-3225. 2021
    https://doi.org/10.21037/jtd-21-792

  • Heterogeneity of the pharmacologic treatment of allergic rhinitis in Europe based on MIDAS and OTCims platforms.
    Bousquet J, Schröder-Bernhardi D, Bachert C, Canonica GW, Cardona V, Costa EM, Czarlewski W, Devillier P, Fonseca JA, Klimek L, Kuna P, Lourenco O, Mullol J, Pfaar O, Pham-Thi N, Samolinski B, Saueressig J, Scadding GK, Stroh AK, Scheire S, Van Ganse E, Zuberbier T.
    Clin Exp Allergy, 51(8): p. 1033-1045. 2021
    https://doi.org/10.1111/cea.13884

  • Intradialytic exercise in end-stage renal disease: An umbrella review of systematic reviews and/or meta-analytical studies.
    Bündchen, DC, Sousa H, Afreixo V, Frontini R, Ribeiro O, Figueiredo D, Costa E.
    Clin Rehabil, 35(6): p. 812-828. 2021
    https://doi.org/10.1177/0269215520986784

  • [ARIA 2019: An Integrated Care Pathway for Allergic Rhinitis in Portugal].
    Fonseca J, Taveira-Gomes T, Pereira AM, Branco-Ferreira M, Carreiro-Martins P, Alves-Correia M, Correia de Sousa J, Costa E, Lourenço O, Morais-Almeida M, Morête A, Regateiro F, Todo Bom A, Bachert C, Pfaar O, Wallace D, Bedbrook A, Czarlewski W, Bousquet J.
    Acta Med Port, 34(2): p. 144-157. 2021
    https://doi.org/10.20344/amp.13777

  • Lesson learned from an international training program on patients medication adherence for healthcare professionals.
    M Maffoni, Traversoni S, Granata N, Weinman J, Lewek P, Kurczewska-Michalak M, Kardas P, Almada M, Midão L, Costa E, Giardini A.
    G Ital Med Lav Ergon, 43(2): p. 137-143. 2021

  • The role of collaborative, multistakeholder partnerships in reshaping the health management of patients with noncommunicable diseases during and after the COVID-19 pandemic.
    A Monaco, Casteig Blanco A, Cobain M, Costa E, Guldemond N, Hancock C, Onder G, Pecorelli S, Silva M, Tournoy J, Trevisan C, Votta M, Yfantopoulos J, Yghemonos S, Clay V, Mondello Malvestiti F, De Schaetzen K, Sykara G, Donde S.
    Aging Clin Exp Res, 33(10): p. 2899-2907. 2021
    https://doi.org/10.1007/s40520-021-01922-y

  • Pre-Frailty and Frailty in Dialysis and Pre-Dialysis Patients: A Systematic Review of Clinical and Biochemical Markers.
    A Pereira, Midão L, Almada M, Costa E.
    Int J Environ Res Public Health, 18(18). 2021
    https://doi.org/10.3390/ijerph18189579

  • "Should WE Stand Together?": A systematic review and meta-analysis of the effectiveness of family-based interventions for adults with chronic physical diseases.
    Sousa H, Ribeiro O, Afreixo V, Costa E, Paúl C, Ribeiro F, Figueiredo D.
    Fam Process, 60(4): p. 1098-1116. 2021
    https://doi.org/10.1111/famp.12707

  • "Together We Stand": A Pilot Study Exploring the Feasibility, Acceptability, and Preliminary Effects of a Family-Based Psychoeducational Intervention for Patients on Hemodialysis and Their Family Caregivers.
    Sousa H, Ribeiro O, Costa E, Frontini R, Paúl C, Amado L, Miranda V, Ribeiro V, Figueiredo D. Healthcare (Basel), 9(11).2021
    https://doi.org/10.3390/healthcare9111585

  • Polypharmacy Management in the Older Adults: A Scoping Review of Available Interventions.
    Kurczewska-Michalak M, Lewek P, Jankowska-Polańska B, Giardini A, Granata N, Maffoni M, Costa E, Midão L, Kardas P.
    Front Pharmacol. Nov 26;12:734045. 2021
    doi:10.3389/fphar.2021.734045

  • Promising Drug Targets and Compounds with Anti-Toxoplasma gondii Activity
    Silva MD, Teixeira C, Gomes P, Borges M
    Microorganisms, 9 (9). 2021
    doi:10.3390/microorganisms9091960

  • Cannabinoids in breast cancer: Differential susceptibility according to subtype
    Almeida CF, Teixeira N, Correia-da-Silva G, Amaral C
    Molecules, 27, 156. 2021
    doi: 10.3390/molecules27010156

  • Cannabidiol disrupts apoptosis, autophagy and invasion processes of placental trophoblasts.
    Alves P, Amaral C, Teixeira N, Correia-da-Silva G
    Archives of Toxicology, 95 (10), 3393-3406. 2021
    doi: 10.1007/s00204-021-03122-z

  • Effects of PI3K inhibition in AI-resistant breast cancer cell lines: autophagy, apoptosis, and cell cycle progression.
    Augusto TV, Amaral C, Wang Y, Chen S, Almeida CF, Teixeira N, Correia-da-Silva G
    Breast Cancer Res Treat, 190 (2), 227-240. 2021
    doi: 10.1007/s10549-021-06376-4.

  • Caffeic acid phenolipids in the protection of cell membranes from oxidative injuries. Interaction with the membrane phospholipid bilayer
    Lopes R, Costa M, Ferreira M, Gameiro P, Fernandes S, Catarino C, Santos-Silva A, Paiva-Martins F
    BBA-Biomembranes, 1863, 183727. 2021
    doi.org/10.1016/j.bbamem.2021.183727

  • Cannabis and Cannabinoids in Reproduction and Fertility: Where We Stand.
    Fonseca BM and Rebelo I Reproductive Sciences, 10, 561. 2021
    doi.org/10.1007/s43032-021-00588-1

  • Antioxidant Effects of Chalcones during the Inflammatory Response: An Overall Review.
    Martins T, Fonseca BM, Rebelo I
    Current Medicinal Chemistry, Volume 28(37), 56. 2021
    doi: 10.2174/0929867328666210511014949

  • Pre-vaccination immune response to COVID-19 in a population in Northeast Portugal.
    Duro M, Duro I, Rebelo I, Moreno F, Pires M, Jacinto S, Pimentel M, Almeida C
    Ir J Med Sci, 12:1-8. 2021
    doi: 10.1007/s11845-021-02799-6.

  • Association of Aquaporin-3, Aquaporin-7, NOS3 and CYBA polymorphisms with hypertensive disorders in women.
    Vieira da Silva I, Santos AC, Matos A, Pereira da Silva A, Soveral G, Rebelo I, Bicho M
    Pregnancy Hypertens, 24:44-49. 2021
    doi: 10.1016/j.preghy.2021.02.008.

  • Differential biological effects of aromatase inhibitors: Apoptosis, autophagy, senescence and modulation of the hormonal status in breast cancer cells
    Augusto TV, Amaral C, Almeida CF, Teixeira N, Correia-da-Silva G
    Molecular and Cellular Endocrinology, 537, 111426. 2021
    doi: 10.1016/j.mce.2021.111426

  • Improving the digital skills of older adults in a COVID-19 pandemic environment.
    Garcia KR, Rodrigues L, Pereira L, Busse G, Irbe M, Almada M, Christensen C, Midao L, Dias I, Heery D, Hardy R, Quarta B, Poulain MM, Bertram M, Karnikowski M, Costa E.
    Educational Gerontology, 47, 196-206. 2021
    doi: 10.1080/03601277.2021.1905216

  • Cell-free DNA as a marker for the outcome of end-stage renal disease patients on haemodialysis.
    Coimbra S, Rocha S, Nascimento H, Valente MJ, Catarino C, Rocha-Pereira P, Sameiro-Faria M, Oliveira JG, Madureira J, Fernandes JC, Miranda V, Belo L, Bronze-da-Rocha E, Santos-Silva A.
    Clinical Kidney Journal, 14, 1371–1378. 2021
    doi: 10.1093/ckj/sfaa115

  • Subpopulations of High-Density Lipoprotein: Friends or Foes in Cardiovascular Disease Risk in Chronic Kidney Disease?
    Coimbra S, Reis F, Valente MJ, Rocha S, Catarino C, Rocha-Pereira P, Sameiro-Faria M, Bronze-da-Rocha E, Belo L, Santos-Silva A.
    Biomedicines, 9(5), 554. 2021
    doi: 10.3390/biomedicines9050554

  • Persistence as a Robust Indicator of Medication Adherence-Related Quality and Performance.
    Menditto E, Cahir C, Malo S, Aguilar-Palacio I, Almada M, Costa E, Giardini A, Peinado MG, Mesquida MM, Mucherino S, Orlando V, Parra-Calderon, CL, Salom EP, Kardas P, Vrijens B.
    International Journal of Environmental Research and Public Health, 18(9), 4872. 2021
    DOI: 10.3390/ijerph18094872

  • Unveiling the mechanism of action behind the anti-cancer properties of cannabinoids in ER+ breast cancer cells: Impact on aromatase and steroid receptors.
    Amaral C, Trouille FM, Almeida CF, Correia-da-Silva G, Teixeira N.
    Journal of Steroid Biochemistry and Molecular Biology, 210, 105876. 2021
    doi: 10.1016/j.jsbmb.2021.105876

  • New Potential Biomarkers for Chronic Kidney Disease Management-A Review of the Literature.
    Lousa I, Reis F, Beirao I, Alves R; Bel L, Santos-Silva, A.
    International Journal of Molecular Sciences, 22(1), 43. 2021
    doi: 10.3390/ijms22010043

  • Vaccines in Congenital Toxoplasmosis: Advances and Perspectives.
    Barros M, Teixeira D, Vilanova M, Correia A, Teixeira N, Borges M.
    Frontiers in Immunology, 11, 621997. 2021
    doi: 10.3389/fimmu.2020.621997

  • Discovery of a multi-target compound for estrogen receptor-positive (ER+) breast cancer: Involvement of aromatase and ERs.
    Almeida CF, Teixeira N, Oliveira A, Augusto TV, Correia-da-Silva G, Ramos MJ, Fernandes PA, Amaral C.
    Biochimie, 181, 65-76.2021
    doi: 10.1016/j.biochi.2020.11.023

  • Sulfated Oligomers of Tyrosol: Toward a New Class of Bioinspired Nonsaccharidic Anticoagulants.
    Alfieri ML, Panzella L, Duarte B, Goncalves-Monteiro S, Marques F, Morato M, Correia-da-Silva M, Verotta L, Napolitano A.
    Biomacromolecules, 22. 2021
    doi: 10.1021/acs.biomac.0c01254

  • Frailty Status and Polypharmacy Predict All-Cause Mortality in Community Dwelling Older Adults in Europe.
    Midao L, Brochado P, Almada M, Duarte M, Paul C, Costa E.
    International Journal of Environmental Research and Public Health, 18 (7):3580. 2021
    doi: 10.3390/ijerph18073580

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).
    Klionsky DJ…. et al
    Autophagy, 17 (1), 1-382. 2021
    doi: 10.1080/15548627.2020.1797280

  • Caring for patients with end-stage renal disease during COVID-19 lockdown: What (additional) challenges to family caregivers?
    Sousa H, Frontini R, Ribeiro O, Paul C, Costa E, Amado L, Miranda V, Ribeiro F, Figueiredo D.
    Scandinavian Journal of Caring Sciences, 00, 1-10. 2021
    doi: 10.1111/scs.12980

  • Neonatal cholestasis: development of a diagnostic decision algorithm from multivariate predictive models.
    Silva ES, Silva HM, Catarino C, Dias CC, Santos-Silva A, Lopes AI.
    European Journal of Pediatrics, 180(5):1477-1486. 2021
    doi: 10.1007/s00431-020-03886-z

  • Concentrations of the endocannabinoid N-arachidonoylethanolamine in the follicular fluid of women with endometriosis: the role of M1 polarised macrophages.
    Fonseca BM, Moreira-Pinto B, Costa L, Felgueira E, Oliveira P, Rebelo I.
    Reproduction, Fertility and Development, 33(4):270-278. 2021
    doi: 10.1071/RD20247

  • Low Doses of Resveratrol Protect Human Granulosa Cells from Induced-Oxidative Stress.
    Moreira-Pinto B, Costa L, Felgueira E, Fonseca BM, Rebelo I.
    Antioxidants, 4;10(4):561. 2021
    doi: 10.3390/antiox10040561

  • The major endocannabinoid anandamide (AEA) induces apoptosis of human granulosa cells.
    Costa L, Moreia-Pinto B, Felgueira E, Ribeiro A, Rebelo I, Fonseca BM.
    Prostaglandins, Leukotrienes & Essential Fatty Acids, 171, 102311. 2021
    doi: 10.1016/j.plefa.2021.102311

  • Soluble mediators potentially involved in pruritus associated to cutaneous T-cell lymphomas and mastocytosis: a cross-sectional study.
    Coimbra S, Miranda M, Abreu M, Oliveira H, Figueiredo A, Lima M, Santos-Silva A.
    Journal of Blood Disorders, vol 8 (1), 1062. 2021

  • From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3,4-DMMC.
    Roque-Bravo R, Carmo H, Valente MJ, Silva JP, Carvalho F, Bastos ML, Dias da Silva D.
    Archives of Toxicology, 95, 1443–1462. 2021
    doi: 10.1007/s00204-021-02990-9

  • The anti-cancer potential of crotoxin in estrogen receptor-positive breast cancer: Its effects and mechanisms of action.
    Almeida CF, Amaral C, Augusto TV, Correia-da-Silva G, de Andrade CM, Torqueti MR, Teixeira N.
    Toxicon, 200, 69-77. 2021
    doi: 10.1016/j.toxicon.2021.07.003

  • Interleukin 6 (rs1800795) and Pentraxin 3 (rs2305619) polymorphisms - association with inflammation and all-cause mortality in end-stage-renal disease patients on dialysis.
    Rocha S, Valente MJ, Coimbra S, Catarino C, Rocha-Pereira P, Oliveira JG, Madureira J, Fernandes JC, Sameiro-Faria M, Miranda V, Belo L, Santos-Silva A, Bronze-da-Rocha E.
    Scientific Reports, 11(1), 14768. 2021
    doi: 10.1038/s41598-021-94075-x

  • IL-31 and IL-8 in cutaneous T-cell lymphoma: looking for their role in itch.
    Abreu M, Miranda M, Castro M, Fernandes I, Cabral R, Santos AH, Fonseca S, Rodrigues J, Leander M, Lau C, Freitas I, Coimbra S, Santos-Silva A, Lima M.
    Advances in Hematology, 5582581. 2021
    doi: 10.1155/2021/5582581





2020
  • European lipodystrophy registry: background and structure.
    von Schnurbein J, Adams C, Akinci B, Ceccarini G, D’Apice MR, Gambineri A, Hennekam RCM, Jeru I, Lattanzi G, Miehle K, Nagel G, Novelli G, Santini F, Santos Silva E, Savage DB, Sbraccia P, Schaaf J, Sorkina E, Tanteles G, Vantyghem MC, Vatier C, Vigouroux C, Vorona E, Araújo-Vilar D, Wabitsch M.
    Orphanet Journal of Rare Diseases 15:17. 2020
    doi: 10.1186/s13023-020-1295-y

  • The interplay between redox signalling and proteostasis in neurodegeneration: In vivo effects of a mitochondria-targeted antioxidant in Huntington’s disease mice.
    Pinho BR, Duarte AI, Canas PM, Moreira P, Murphy MP, Oliveira JMA.
    Free Radical Biology and Medicine 146:372 38. 2020

  • School-based soccer practice is an effective strategy to improve cardiovascular and metabolic risk factors in overweight children.
    Seabra A, Brito J, Figueiredo P, Beirão L, Seabra A, Carvalho MJ, Abreu S, Vale S, Pedretti A, Nascimento H, Belo L, Rêgo C.
    Prog Cardiovasc Dis. 63(6):807-812. 2020
    doi: 10.1016/j.pcad.2020.07.007

  • Toxoplasma Gondii Infection reduces serum progesterone levels and adverse effects at the maternal-foetal interface
    Brito C, M Silva T, M Castro M, Wyrwas W, Oliveira B, Fonseca BM, Oliveira P, W Roberts C, Teixeira N, Borges M.
    Parasite Immunology 42(2):e12690. 2020
    doi: 10.1111/pim.12690

  • Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence.
    Bousquet J, Schünemann HJ, Togias A, Bachert C, Erhola M, Hellings PW, Klimek L, Pfaar O, Wallace D, Ansotegui I, Agache I, Bedbrook A, Bergmann KC, Bewick M, Bonniaud P, Bosnic-Anticevich S, Bossé I, Bouchard J, Boulet LP, Brozek J, Brusselle G, Calderon MA, Canonica WG, Caraballo L, Cardona V, Casale T, Cecchi L, Chu DK, Costa EM, …., Waserman S, et al.
    J Allergy Clin Immunol. Jan;145(1):70-80.e3. 2020
    doi: 10.1016/j.jaci.2019.06.049

  • Patient Centric Pharmaceutical Drug Product Design-The Impact on Medication Adherence.
    Menditto E, Orlando V, De Rosa G, Minghetti P, Musazzi UM, Cahir C, Kurczewska-Michalak M, Kardas P, Costa E, Sousa Lobo JM, Almeida IF.
    Pharmaceutics. Jan 3;12(1):44. 2020
    doi: 10.3390/pharmaceutics12010044

  • Methodological features of quantitative studies on medication adherence in older patients with chronic morbidity: A systematic review.
    Granata N, Traversoni S, Kardas P, Kurczewska-Michalak M, Costa E, Midão L, Giardini A. Patient Educ Couns. Oct;103(10):2132-2141. 2020
    doi: 10.1016/j.pec.2020.04.006

  • The Need to Develop Standard Measures of Patient Adherence for Big Data: Viewpoint.
    Kardas P, Aguilar-Palacio I, Almada M, Cahir C, Costa E, Giardini A, Malo S, Massot Mesquida M, Menditto E, Midão L, Parra-Calderón CL, Pepiol Salom E, Vrijens B.
    J Med Internet Res. 22(8):e18150. 2020
    doi: 10.2196/18150

  • Managing Allergic Rhinitis in the Pharmacy: An ARIA Guide for Implementation in Practice.
    Lourenço O, Bosnic-Anticevich S, Costa E, Fonseca JA, Menditto E, Cvetkovski B, Kritikos V, Tan R, Bedbrook A, Scheire S, Bachert C, Białek S, Briedis V, Boussery K, Canonica GW, Haahtela T, Kuna P, Novellino E, Samoliński B, Schünemann HJ, Wallace D, Bousquet J.
    Pharmacy (Basel). 8(2):85. 2020
    doi: 10.3390/pharmacy8020085

  • Cognitive performance in older adults across Europe based on the SHARE database.
    Barbosa R, Midão L, Almada M, Costa E.
    Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 3:1-16. 2020
    doi: 10.1080/13825585.2020.1799927

  • Instrumental Activities of Daily Living (iADL) Limitations in Europe: An Assessment of SHARE Data.
    Portela D, Almada M, Midão L, Costa E.
    Int J Environ Res Public Health. 17(20):E7387. 2020
    doi: 10.3390/ijerph17207387

  • Prevalence of fall and associated factors among community dwelling European Older Adults: a cross-sectional study.
    Almada M, Brochado P, Portela D, Midão L, Costa E.
    J Frailty Aging. 2020
    https://doi.org/10.14283/jfa.2020.44

  • Computer Skills Among the Community Dwelling 55+ European Population Based on Survey of Health, Ageing, and Retirement in Europe.
    Midão L, Pedreiro E, Santos Pinho M, Dias I, Ramos Garcia K, Almada M, Silva Rodrigues L, Christensen C, Teixeira Pereira P, Bertram M, Busse G, Quarta B, Poulain MM, Heery D, Ruseva G, Irbe MM, Amaral M, Costa E.
    International Journal of Digital Literacy and Digital Competence. 11(1):31-45. 2020
    doi: 10.4018/IJDLDC.2020010102

  • In vitro assessment of polyethylene glycol and polyvinylpyrrolidone as hydrophilic additives on bioseparation by polysulfone membranes.
    Kohlová M, Amorim CG, Araújo A, Santos-Silva A, Solich P, Montenegro MCBS.
    Journal of Materials Science. 55, pages 1292–1307. 2020

  • Neutrophil gelatinase-associated lipocalin detection using a sensitive electrochemical immunosensing approach.
    Neves M, Nouws H, Santos-Silva A, Delerue-Matos C.
    Sensors & Actuators: B. Chemical. 304, 127285. 2020
    https://doi.org/10.1016/j.snb.2019.127285

  • Linkage of typically cytosolic peroxidases to erythrocyte membrane – a possible mechanism of protection in Hereditary Spherocytosis.
    Rocha S, Rocha-Pereira P, Cleto E, Ferreira F, Belo L, Santos-Silva A.
    Biochimica et Biophysica Acta (BBA) – Biomembrane. 1862 (3 ): 183172 (12 pages). 2020
    doi: 10.1016/j.bbamem.2019.183172. IF 3.79I

  • Membrane with Alpha-tocopherol and Alpha-lipoic Acid to Suppress Oxidative Stress Induced by Hemodialysis Treatment.
    Kohlová M, Amorim CG, Araújo A, Santos-Silva A, Solich P, Montenegro MCBS.
    Macromolecular Bioscience. 20(7) : e2000046. 2020
    doi: 10.1002/mabi.202000046

  • Cell-free DNA as a marker for the outcome of end-stage renal disease patients on hemodialysis.
    Coimbra S, Rocha S, Nascimento H, Valente MJ, Catarino C, Rocha-Pereira P, Sameiro-Faria M, Oliveira JG, Madureira J, Fernandes JC, Miranda V, Belo L, Bronze-da-Rocha E, Santos-Silva A.
    Clinical Kidney Journal. 10.1093/ckj/sfaa115. 2020

  • Neonatal cholestasis over time: changes in epidemiology and outcome in a cohort of 154 patients from a Portuguese tertiary center.
    Santos Silva E, Almeida A, Frutuoso S, Martins E, Valente MJ, Santos-Silva A, Lopes AI.
    Frontiers in Pediatrics 30;8:351. 2020
    doi: 10.3389/fped.2020.00351

  • Protective effect of olive oil polyphenol phase II sulfate conjugates on erythrocyte oxidative-induced hemolysis.
    Fernandes S, Ribeiro C, Paiva-Martins F, Catarino C, Santos-Silva A.
    Food & Function. 11(10):8670-8679. 2020
    doi: 10.1039/d0fo01690j

  • Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models.
    Bravo RR, Carmo H, Silva JP, Valente MJ, Carvalho F, Bastos ML, Dias da Silva D.
    Archives of Toxicology. 94, 609–629. 2020
    doi: 10.1007/s00204-019-02638-9

  • The interplay between autophagy and apoptosis mediates toxicity triggered by synthetic cathinones in human kidney cells.
    Vaz I, Carvalho T, Valente MJ, Castro A, Araújo AM, Bastos ML, Carvalho M.
    Toxicology Letters. 331, 42-52. 2020
    doi: 10.1016/j.toxlet.2020.05.025

  • Dissimilar effects of curcumin on human granulosa cells: Beyond its anti-oxidative role.
    Beatriz Moreira-Pinto, Lia Costa , Bruno M Fonseca , Irene Rebelo.
    Reprod Toxicol. 95:51-58. 2020
    doi: 10.1016/j.reprotox.2020.04.069

  • Review on the effects of obesity treatment with acupuncture and phytoacupuncture.
    Rosa Vilares Santos, Jorge Magalhães Rodrigues , MariaIrene Jesus.
    World Journal of Acupuncture – Moxibustion. 30:223–228. 2020

  • Impact of tetrahydrocannabinol on the endocannabinoid 2-arachidonoylglycerol metabolism: ABHD6 and ABHD12 as novel players in human placenta.
    Maia J, Fonseca BM, Cunha SC, Braga J, Gonçalves D, Teixeira N, Correia-da-Silva G.
    Biochim Biophys Acta Mol Cell Biol Lipids. 1865(12):158807. 2020
    doi: 10.1016/j.bbalip.2020.158807

  • The Cannabinoid Delta-9-tetrahydrocannabinol Disrupts Estrogen Signaling in Human Placenta.
    Maia J, Almada M, Midão L, Fonseca BM, Braga J, Gonçalves D, Teixeira N, Correia-da-Silva G.
    Toxicol Sci. 177(2):420-430. 2020
    doi: 10.1093/toxsci/kfaa110

  • The endocannabinoid 2-arachidonoylglycerol promotes endoplasmic reticulum stress in placental cells.
    Almada M, Costa L, Fonseca B, Alves P, Braga J, Gonçalves D, Teixeira N, Correia-da-Silva G.
    Reproduction. Aug;160(2):171-180. 2020
    doi: 10.1530/REP-19-0539

  • Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol.
    Alves P, Amaral C, Teixeira N, Correia-da-Silva G.
    Pharmacol Res. 157:104822. 2020
    doi: 10.1016/j.phrs.2020.104822

  • Estrogen receptor-positive (ER+) breast cancer treatment: are multi-target compounds the next promising approach?
    Cristina Ferreira Almeida, Ana Oliveira, Maria João Ramos, Pedro A. Fernandes, Natércia Teixeira, Cristina Amaral.
    Biochemical Pharmacology. 113989. 2020
    http://dx.doi.org/10.1016/j.bcp.2020.113989

  • The potential clinical benefit of targeting androgen receptor (AR) in estrogen-receptor positive breast cancer cells treated with Exemestane.
    Cristina Amaral, Tiago Augusto, Marta Almada, Sara C. Cunha, Georgina Correia-da-Silva, Natércia Teixeira.
    Biochim Biophys Acta Mol Basis Dis. 1866(5):165661. 2020
    doi: 10.1016/j.bbadis.2019.165661

  • The fundamental role of the endocannabinoid system in endometrium and placenta: implications in pathophysiological aspects of uterine and pregnancy disorders.
    Maia J, Fonseca BM, Teixeira N, Correia-da-Silva G.
    Human Reproduction Update. 2020
    DOI:10.1093/humupd/dmaa005

  • Decidual NK cell-derived conditioned medium from miscarriages affects endometrial stromal cell decidualisation: endocannabinoid anandamide and tumour necrosis factor-α crosstalk.
    Fonseca BM, Cunha SC, Gonçalves D, Mendes A, Braga J, Correia-da-Silva G, Teixeira NA. Hum Reprod. Jan 28. pii: dez260. 2020
    doi:10.1093/humrep/dez260

  • Cannabidiol (CBD) but not tetrahydrocannabinol (THC) dysregulate in vitro decidualization of human endometrial stromal cells by disruption of estrogen signaling.
    Almada M, Amaral C, Oliveira A, Fernandes PA, Ramos MJ, Fonseca BM, Correia-da-Silva G, Teixeira N.
    Reprod Toxicol. Jan 14;93:75-82. 2020
    doi: 10.1016/j.reprotox.2020.01.003

  • Synthetic cannabinoids JWH-018, JWH-122, UR-144 and the phytocannabinoid THC activate apoptosis in placental cells.
    Almada M, Alves P, Fonseca BM, Carvalho F, Queirós CR, Gaspar H, Amaral C, Teixeira NA, Correia-da-Silva G.
    Toxicol Lett. Feb 1;319:129-137. 2020
    doi:10.1016/j.toxlet.2019.11.004




2019
  • Next-generation ARIA Care Pathways for Rhinitis and Asthma: A Model for Multimorbid Chronic Diseases
    Bousquet J, Schünemann H, Togias A, …., Costa E, … Zidarn M.
    Clin Transl Allergy. Sep 9;9:44. 2019

  • Guidance to 2018 good practice: ARIA digitally-enabled, integrated, person-centred care for rhinitis and asthma.
    Bousquet J, Bedbrook A, …., Costa E, … Wallace DV.
    Clin Transl Allergy. 9:16. 2019

  • A Microfluidic Deformability Assessment of Pathological Red Blood Cells Flowing in a Hyperbolic Converging Microchannel.
    Faustino V, Rodrigues R, Pinho D, Costa E, Santos-Silva A, Miranda V, Amaral J, Lima R.
    Micromachines. 10(10), 645. 2019

  • The Reference Site Collaborative Network of the European Innovation Partnership on Active and Healthy Ageing.
    Bousquet J, Illario M, Farrell J, …, Costa E, … Zurkuhlen Aj.
    Translational Medicine @ Unisa. 19:66-81. 2019

  • Intergenerational Programs Review: Study Design and Characteristics of Intervention, Outcomes, and Effectiveness.
    Martins T, Midão L, Martínez-Veiga S, Dequech L, Busse G, Bertram M, McDonald A, Gilliland G, Orte C, Vives M, Costa E.
    Journal of Intergenerational Relationships. 17:1, 93-109. 2019

  • Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases—Meeting Report (Part 2).
    Bousquet J, Pham-Thi N, …. Costa E, …, Zuberbier T
    J Thorac Dis. 11(9): 4072-4084. 2019

  • Next-generation care pathways for allergic rhinitis and asthma multimorbidity: a model for multimorbid non-communicable diseases—Meeting Report (Part 1).
    N Bousquet J, Pham-Thi N, …. Costa E, …, Zuberbier T.
    Thorac Dis. 11(8): :3633-3642. 2019

  • 2019 ARIA Care pathways for allergen immunotherapy.
    Bousquet J, Pfaar O, Togias A, …, Costa E, …, Rolland C.
    Allergy. Nov;74(11):2087-2102. 2019

  • Social support and treatment adherence in patients with end‐stage renal disease: A systematic review.
    Sousa H, Ribeiro O, Paúl C, Costa E, Miranda V, Ribeiro F, Figueiredo D.
    Seminars in Dialysis. 32 (6):562-574. 2019

  • ARIA Pharmacy 2018 "Allergic Rhinitis Care Pathways for Community Pharmacy": AIRWAYS ICPs Initiative (European Innovation Partnership on Active and Healthy Ageing, DG CONNECT and DG Santé) POLLAR (Impact of Air POLLution on Asthma and Rhinitis) GARD Demonstration Project.
    Bosnic-Anticevich S, Costa E, Menditto E, et al.
    Allergy. 74(7):1219-1236. 2019

  • Characterization of a Cohort of Patients with Arterial Thrombosis from the Georgian Adjarian Population.
    Garakanidze S, Costa E, Bronze-Rocha E, Santos-Silva A, Nikolaishvili G, Nakashidze I, Kakauridze N, Glonti S, Khukhunaishvili R, Koridze M, Ahmad S.
    Current Trends in Biotechnology and Pharmacy. 13(3): 259-269. 2019

  • Dairy Product Intake in Older Adults across Europe Based On the SHARE Database.
    Ribeiro I, Gomes M, Figueiredo D, Lourenco J, Paul C, Costa E.
    Journal of Nutrition in Gerontology and Geriatrics. 38(3):297-306. 2019

  • Prevalence of frailty status among the European elderly population: Findings from the Survey of Health, Aging and Retirement in Europe.
    Manfredi G, Midão L, Paul C, Cena C, Duarte M, Costa E.
    Geriatr Gerontol Int. 19(8):723-729. 2019

  • Mobile technology offers novel insights into the control and treatment of allergic rhinitis: The MASK study.
    Bédard A, Basagaña X, Anto JM, …, Costa E, …., Bousquet J.
    J Allergy Clin Immunol. Jul;144(1):135-143. 2019

  • Adherence to treatment in allergic rhinitis using mobile technology. The MASK Study.
    Menditto E, Costa E, Midão L, et al.
    Clin Exp Allergy. Apr;49(4):442-460. 2019

  • TNF-Mediated Compensatory Immunity to Mycobacterium avium in the Absence of Macrophage Activation by IFN-γ.
    Resende M, Cardoso MS, Fróis-Martins R, Margarida Borges, Michael B. Jordan, M
    J Immunol. 203(9):2451-2458. 2019
    doi:10.4049/jimmunol.1801594

  • Endocrine parametres in association with bone mineral accrual in young female vocational ballet dancers.
    Amorim T, Metsios GS, Flouris AD, Neville A, Gomes TH, Wyon M, Marques F, Nogueira L, Adubeiro N, Jamurtas AZ, Mais J, Koutedakis Y.
    Archives of osteoporosis (DOI.org/10.1007/s11657-019-0596-z). 2019

  • The potential clinical benefit of targeting androgen receptor (AR) in estrogen-receptor positive breast cancer cells treated with Exemestane.
    Amaral C, Augusto TV, Almada M, Cunha SC, Correia-da-Silva G, Teixeira N.
    Biochim Biophys Acta Mol Basis Dis. Dec 28;1866(5):165661. 2019
    doi: 10.1016/j.bbadis.2019.165661.

  • Effects of new C6-substituted steroidal aromatase inhibitors in hormone-sensitive breast cancer cells: Cell death mechanisms and modulation of estrogen and androgen receptors.
    Augusto TV, Amaral C, Varela CL, Bernardo F, da Silva ET, Roleira FFM, Costa S, Teixeira N, Correia-da-Silva G.
    J Steroid Biochem Mol Biol. Dec;195:105486. 2019
    doi:10.1016/j.jsbmb.2019.105486.

  • Anandamide targets aromatase: A breakthrough on human decidualization.
    Almada M, Oliveira A, Amaral C, Fernandes PA, Ramos MJ, Fonseca B, Correia-da-Silva G, Teixeira N.
    Biochim Biophys Acta Mol Cell Biol Lipids. Dec;1864(12):158512. 2019
    doi:10.1016/j.bbalip.2019.08.008.

  • A novel GC-MS methodology to evaluate aromatase activity in human placental microsomes: a comparative study with the standard radiometric assay.
    Augusto TV, Cunha SC, Amaral C, Fernandes JO, da Silva ET, Roleira FFM, Teixeira N, Correia-da-Silva G.
    Anal Bioanal Chem. Oct;411(26):7005-7013. 2019
    doi:10.1007/s00216-019-02076-7.

  • Uterine histopathological changes induced by acute administration of tamoxifen and its modulation by sex steroid hormones.
    Sá SI, Maia J, Bhowmick N, Silva SM, Silva A, Correia-da-Silva G, Teixeira N, Fonseca BM.
    Toxicol Appl Pharmacol. Jan 15;363:88-97. 2019
    doi:10.1016/j.taap.2018.11.015.

  • Histological and toxicological evaluation, in rat, of a P-glycoprotein inducer and activator: the 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5).
    Rocha-Pereira C, Silva V, Costa VM, Silva R, Garcia J, Monteiro S, Duarte-Araújo M, Santos-Silva A, Coimbra S, Dinis-Oliveira RJ, Lopes C, Silva P, Long S, Sousa E, Bastos ML, Remião F.
    Experimental and Clinical Sciences Journal, 18 : 697-722. 2019

  • A microfluidic deformability assessment of pathological red blood cells flowing in a hyperbolic converging microchannel.
    Faustino V, Rodrigues RO, Pinho D, Costa E, Santos-Silva A, Miranda V, Amaral JS, Lima R.
    Micromachines, 10 : 645 (15pg) FI: 2.426. 2019
    doi: 10.3390/mi10100645

  • The biocompatibility and bioactivity of hemodialysis membranes: their impact in end-stage renal disease.
    Kohlová M, Amorim CG, Araújo A, Santos-Silva A, Solich P, Montenegro MCBS.
    Journal of Artificial Organs, 22 (1) : 14-28. 2019

  • Weight loss achieved by bariatric surgery modifies high-density lipoprotein subfractions and low-density lipoprotein oxidation towards atheroprotection.
    Coimbra S, Reis F, Ferreira C, Nunes S, Viana S, Catarino A, Rocha-Pereira P, Belo L, Monteiro L, Catarino C, Santos-Silva A.
    Clinical Biochemistry, 63:46-53. 2019

  • The protective role of adiponectin for lipoproteins in end-stage renal disease patients - relationship with diabetes and body mass index.
    Coimbra S, Reis F, Nunes S, Viana SD, Valente MJ, Rocha S, Catarino C, Rocha-Pereira P, Bronze-da-Rocha E, Sameiro-Faria M, Oliveira JG, Madureira J, Fernandes JC, Miranda V, Belo L, Santos-Silva A.
    Oxidative Medicine and Cellular Longevity, special issue "Lipids and Redox Signaling in Cardiovascular and Kidney Disease", 3021785. 2019
    doi: 10.1155/2019/3021785.
    eCollection 2019.

  • Disposable electrochemical immunosensor for analysis of cystatin C, a CKD biomarker.
    Lopes P, Costa-Rama E, Beirão I, Nouws HPA, Santos-Silva A, Delerue-Matos C.
    Talanta, The International Journal of Pure and Applied Analytical Chemistry, 201 : 211-216. 2019

  • Long Pentraxin 3 as a Broader Biomarker for Multiple Risk Factors in End-Stage Renal Disease – Association with All-Cause Mortality.
    Valente MJ, Rocha S, Coimbra S, Catarino C, Rocha-Pereira P, Bronze-da-Rocha E, Oliveira JG, Madureira J, Fernandes JC, Sameiro-Faria M, Miranda V, Belo L, Santos-Silva A.
    Mediators of Inflammation, Volume, Article ID 3295725, 12 pages. 2019
    https://doi.org/10.1155/2019/3295725

  • Hepcidin and diabetes are independently related with soluble transferrin receptor levels in chronic dialysis patients.
    Belo L, Valente MJ, Rocha S, Coimbra S, Catarino C, Bronze-da-Rocha E, Rocha-Pereira P, Sameiro-Faria M, Oliveira JG, Madureira J, Fernandes JC, Miranda V, Santos-Silva A.
    Renal Failure, 41 (1) : 662-672. 2019
    doi: 10.1080/0886022X.2019.1635893.

  • C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships.
    Roleira FMF, Varela C, Amaral C, Costa SC, Correia-da-Silva G, Moraca F, Costa G, Alcaro S, Teixeira NAA, Tavares da Silva EJ.
    J Med Chem. Apr 11;62(7):3636-3657. 2019
    doi: 10.1021/acs.jmedchem.9b00157.
    Epub 2019 Mar 26.

  • Effects of cannabis tetrahydrocannabinol on endocannabinoid homeostasis in human placenta.
    Maia J, Midão L, Cunha SC, Almada M, Fonseca BM, Braga J, Gonçalves D, Teixeira N, Correia-da-Silva G.
    Arch Toxicol. Mar;93(3):649-658. 2019
    doi: 10.1007/s00204-019-02389-7.
    Epub 2019 Jan 18.

  • Uterine histopathological changes induced by acute administration of tamoxifen and its modulation by sex steroid hormones.
    Sá SI, Maia J, Bhowmick N, Silva SM, Silva A, Correia-da-Silva G, Teixeira N, Fonseca BM.
    Toxicol Appl Pharmacol. Jan 15;363:88-97. 2019
    doi: 10.1016/j.taap.2018.11.015.
    Epub 2018 Nov 29.

  • Synthetic cannabinoids and endometrial stromal cell fate: Dissimilar effects of JWH-122, UR-144 and WIN55,212-2.
    Fonseca BM, Fernandes R, Almada M, Santos M, Carvalho F, Teixeira NA, Correia-da-Silva G.
    Toxicology. Feb 1;413:40-47. 2019
    doi: 10.1016/j.tox.2018.11.006.
    Epub 2018 Nov 28.

  • essential oils on estrogen receptor-positive breast cancer cells.
    Hassan El-Abid, Cristina Amaral, Sara C. Cunha, Tiago V. Augusto, José O. Fernandes, Georgina Correia-da-Silva, Natércia Teixeira, Mohieddine Moumnia.
    Journal of Functional Foods, 59:261–271. 2019
    doi: 10.1016/j.jff.2019.05.042.

  • How does toxoplasmosis affect the maternal-foetal immune interface and pregnancy?
    Borges, M ; Tania Magalhaes Silva; Carina Brito; Natercia Teixeira; Craig W Roberts;
    PARASITE IMMUNOLOGY, VOLUME: 41, ISSUE: 3, PUBLISHED: 2019




2018
  • Current Issues Regarding Prenatal Diagnosis of inborn Errors of Cholesterol Biosynthesis.
    Cardoso ML , Barbosa , Fortuna AM, Marques F.
    In Prenatal diagnosis – Morphology Scan and Invasive Methods. Chap7. (DOI: 10.5772/intechopen.78038). 2018.

  • Quantitative Proteomic Analysis of Skeletal Muscle Detergent- Resistant Membranes in a Smith-Lemli-Opitz Syndrome Mouse.
    ML Cardoso, R Vitorino, H Reguengo, S Casal, R Fernandes, I Duarte, S Lamas, R Alves, F Amado and F Marques
    Chapter 8 (DOI: 10.5772/intechopen.78037). 2018

  • Aged rats are more vulnerable than adolescents to “ecstasy”-induced toxicity.
    R. Feio-Azevedo, V. M. Costa, D. J. Barbosa, A. Teixeira-Gomes, I. Pita, S. Gomes, F. C. Pereira, M. Duarte-Araújo, J. A. Duarte, F. Marques, E. Fernandes, M. L. Bastos, F. Carvalho, J. P. Capela.
    Archives of Toxicology July, Volume 92, Issue 7, pp 2275–2295 (IF- 5,728). 2018

  • Genetic variation in Wnt/β-catenin and ER signalling pathways in female and male elite dancers and its associations with low bone mineral density: a cross-section and longitudinal study.
    T. Amorim, C. Durães, J. C. Machado, G. S. Metsios, M. Wyon, J. Maia, A. D. Flouris, F. Marques, L. Nogueira N. Adubeiro, Y. Koutedakis.
    Osteoporosis International, Volume 29, Issue 10, pp 2261–2274 (IF 3,53). 2018

  • The Antitumor Activity of a Lead Thioxanthone is Associated with Alterations in Cholesterol Localization.
    Lima RT, Sousa D, Gomes AS, Mendes N, Matthiesen R, Pedro M, Marques F, Pinto MM, Sousa E, Vasconcelos MH.
    Molecules. Dec 12;23(12). pii: E3301. 2018
    doi: 10.3390/molecules23123301. (IF 3,268).

  • Methylenetetrahydrofolate reductase gene polymorphism (C677T) as a risk factor of arterial thrombosis in Georgian patients.
    Garakanidze S, Costa E, Bronze-Rocha E, Santos-Silva A, Nikolaishvili G, Nakashsidze I, Kakauridze, Glonti S, Khukhunaishivili R, Koridze M, Ahmad S.
    Clinical and Applied Thrombosis/Hemostasis, 24 (7) : 1061-1066. 2018

  • Metabolic syndrome in human immunodeficiency virus-infected patients.
    Duro M, Manso MC, Barreira S, Rebelo I, Medeiros R, Almeida C.
    Int J STD AIDS, Jan 1:956462418775188. 2018
    doi: 10.1177/0956462418775188. [Epub ahead of print]

  • Polypharmacy prevalence among older adults based on the survey of health, ageing and retirement in Europe.
    Midão L, Giardini A, Menditto E, Kardas P, Costa E.
    Arch Gerontol Geriatr, 78:213-220. 2018

  • Nutritional, chemical and antioxidant/pro-oxidant profiles of silverskin, a coffee roasting by-product.
    Costa ASG, Alves RC, Vinha AF, Costa E, Costa CSG, Nunes MA, Almeida AA, Santos-Silva A, Oliveira MBPP.
    Food Chem, 267:28-35. 2018

  • A cornerstone of healthy aging: do we need to rethink the concept of adherence in the elderly?
    Giardini A, Maffoni M, Kardas P, Costa E.
    Patient Prefer Adherence, Jun 11; 12:1003-1005. 2018

  • Vascular biosafety of commercial hydroxyapatite particles: discrepancy between blood compatibility assays and endothelial cell behavior.
    Santos C, Turiel S, Sousa Gomes P, Costa E, Santos-Silva A, Quadros P, Duarte J, Battistuzzo S, Fernandes MH.
    J Nanobiotechnology, Mar 22;16(1):27. 2018

  • Geolocation with respect to personal privacy for the Allergy Diary app - A MASK study.
    Samreth D, Arnavielhe S, Ingenrieth F, …, Costa E, … , Poncelet P.
    World Allergy Organization Journal, Jul 16; 11(1):15. 2018
    doi: 10.1186/s40413-018-0194-3. eCollection 2018.

  • Hormone-dependent breast cancer: Targeting autophagy and PI3K overcomes Exemestane-acquired resistance.
    Amaral C., Augusto T.V., Tavares-da-Silva E., Roleira F.M.F., Correia-da-Silva G., Teixeira N.
    J Steroid Biochem Mol Biol, Oct; 183:51-61. 2018
    doi: 10.1016/j.jsbmb.2018.05.006.

  • Cannabinoid-induced cell death in endometrial cancer cells: involvement of TRPV1 receptors in apoptosis.
    Fonseca BM, Correia-da-Silva G, Teixeira NA.
    J Physiol Biochem, 74(2):261-72. 2018

  • Effects of tamoxifen on neuronal morphology, connectivity and biochemistry of hypothalamic ventromedial neurons: Impact on the modulators of sexual behavior.
    Sa SI, Teixeira N, Fonseca BM.
    Neurobiol Dis, 109(Pt A):33-43. 2018

  • The biocompatibility and bioactivity of hemodialysis membranes: their impact in end-stage renal disease.
    Kohlová M, Amorim CG, Araújo A, Santos-Silva A, Solich P, Montenegro MCBS.
    Journal of Artificial Organs, In Press 1-15. 2018
    doi: 10.1007/s10047-018-1059-9

  • Vascular biosafety of comercial hydroxiapatite particles: discrepancy between blood compatibility assays and endothelial cell behavior.
    Santos C, Turiel S, Gomes Ps, Costa E, Santos-Silva A, Quadros P, Duarte J, Battistuzzo S, Fernandes MH
    Journal of Nanobiotechnology, 16 (1): 27. 2018
    doi: 10.1186/s12951-018-0357-y

  • Neutrophil Elastase Inhibitors and Chronic Kidney Disease.
    Bronze-da-Rocha E, Santos-Silva A.
    International Journal of Biological Sciences, 14 (10): 1343-1360. 2018
    doi: 10.7150/ijbs.26111. eCollection 2018. Review.

  • Influence of the 6-month physical activity programs on renal function in obese boys.
    Lousa I, Nascimento H, Rocha S, Catarino C, Reis F, Rêgo C, Santos-Silva A, Seabra A, Ribeiro S, Belo L.
    Pediatric Research, 83:1011–1015. 2018
    doi: 10.1038/pr.2018.15

  • Impact of weight loss on inflammation and red blood cells biomarkers after laparoscopic gastric banding surgery.
    Coimbra S, Ferreira C, Belo L, Rocha-Pereira P, Catarino A, Monteiro L, Catarino C, Santos-Silva A.
    Journal of Investigative Medicine, 66:304–308. 2018

  • Cardiovascular risk factors are correlated with decreased cognitive function among older adults across Europe based on the SHARE database.
    Lourenço J, Serrano A, Santos-Silva A, Gomes M, Afonso C, Freitas P, Paúl C, Costa E.
    Aging and Disease, 9(1): 90-101. 2018
    doi: 10.14336/AD.2017.0128

  • Acquired resistance to aromatase inhibitors: where we stand!
    Augusto T, Correia-da-Silva G, Rodrigues C, Teixeira N, Amaral C. Endocrine Related Cancer, 25 (5): R283-R301. 2018
    doi: 10.1530/ERC-17-0425

  • Revisiting the metabolic syndrome: the emerging role of aquaglyceroporins.
    da Silva IV, Rodrigues JS, Rebelo I, Miranda JPG, Soveral G. Cell Mol Life Sci. 2018 Jun; 75(11):1973-1988.
    Epub 2018 Feb 20. (Review)
    doi: 10.1007/s00018-018-2781-4




2017
  • Bone mineral density in vocational and professional ballet dancers.
    Amorim, T. and Koutedakis, Y. and Nevill, A. and Wyon, M. and Maia, J. and Machado, J. C. and Marques, F. and Metsios, G. S. and Flouris, A. D. and Adubeiro, N. and Nogueira, L. and Dimitriou, Lygeri (2017).
    Osteoporosis International, 28 (10). pp. 2903-2912. ISSN 0937-941X. 2017 - IF. 4,099. 2017
    (Official URL: https://doi.org/10.1007/s00198-017-4130-0)

  • Bone mass of female dance students prior to professional dance training: A cross-sectional study.
    Amorim T, Metsios GS, Wyon M, Nevill AM, Flouris AD, Maia J, Teixeira E, Machado JC, Marques F, Koutedakis Y.
    PLoS One. Jul 5;12(7):e0180639. 2017
    doi: 10.1371/journal.pone.0180639. (IF- 2,766).

  • Cardiovascular risk factors are correlated with decreased cognitive function among older adults across Europe based on the SHARE database.
    Lourenço J, Serrano A, Santos-Silva A, Gomes M, Afonso C, Freitas P, Paúl C, Costa E.
    Aging and Disease, 2017 (In Press)

  • The cross-talk between renal function, inflammation and psoriasis vulgaris.
    Coimbra S, Oliveira H, Rocha-Pereira P, Figueiredo A, Santos-Silva A.
    British Journal of Dermatology, 176(3): 829-831. 2017
    doi: 10.1111/bjd.14913

  • Physical inactivity among older adults across Europe based on the SHARE database.
    Gomes M, Figueiredo D, Teixeira L, Poveda V, Paúl C, Santos-Silva A, Costa E.
    Age and Aging, 46(1): 71-77. 2017
    doi: 10.1093/ageing/afw165

  • Coffee: A Dietary Intervention on Type 2 Diabetes?
    Rebelo I, Casal S.
    Curr Med Chem.; 24(4):376-383. 2017 (Review).
    doi: 10.2174/0929867323666161003123717

  • Cannabinoids as modulators of cell death: clinical applications and future directions.
    Fonseca BM., Teixeira NA, Correia-da-Silva G.
    Reviews in Physiology, Biochemistry and Pharmacology, 173: 63–88; 2017
    doi: 10.1007/112_2017_3

  • Frailty in end-stage renal disease patients under dialysis and its association with clinical and biochemical markers.
    Poveda V, Filgueiras M, Miranda V, Santos-Silva A, Paúl C, Costa E.
    The Journal of Frailty & Aging, 6(2): 103-106. 2017

  • Renal cell carcinoma: a critical analysis of metabolomic biomarkers emerging from current model systems.
    Rodrigues D, Monteiro M, Jerónimo C, Henrique R, Belo L, de Lourdes Bastos M, de Pinho PG, Carvalho M.
    Translational Research, 180:1-11. 2017
    doi: 10.1016/j.trsl.2016.07.018

  • Methylone and MDPV activate autophagy in human dopaminergic SH-SY5Y cells: a new insight into the context of β-keto amphetamines-related neurotoxicity.
    Valente MJ, Amaral C, Correia-da-Silva G, Duarte J, Bastos NL, Carvalho F, Pinho P, Carvalho M.
    Archives of Toxicology, 91(11):3663-3676. 2017
    doi: 10.1007/s00204-017- 1984-z

  • Building bridges for innovation in ageing: Synergies between Action Groups of the EIP on AHA.
    Bousquet J, Bewick M, Cano A, Eklund P, Fico G, … Costa E, …. de Oliveira-Alves B.
    The Journal of Nutrition Health and Aging, 21(1):92-104. 2017

  • Clinical practices among healthcare professionals concerning neonatal jaundice and pale stools.
    Santos Silva E, Moreira Silva H, Azevedo Lijnzaat L, Melo C, Costa E, Martins E, Lopes AI.
    Eur J Pediatr., 176(3):361-369. 2017

  • Cannabinoids as modulators of cell death: clinical applications and future directions.
    Fonseca BM., Teixeira NA, Correia-da-Silva G.
    Reviews in Physiology, Biochemistry and Pharmacology, 173: 63–88. 2017
    doi: 10.1007/112_2017_3.

  • Frailty in end-stage renal disease patients under dialysis and its association with clinical and biochemical Markers.
    Poveda V, Filgueiras M, Miranda V, Santos-Silva A, Paúl C, Costa E.
    The Journal of Frailty & Aging, 6 (2) : 103-106. 2017

  • Physical exercise intervention at school improved hepcidin, inflammation and iron metabolism in overweight and obese children and adolescents.
    Coimbra S, Catarino C, Nascimento H, Alves AI, Medeiros F, Bronze-da-Rocha E), Costa E, Rocha-Pereira P, Aires L, Seabra A, Mota J, Mansilha HF, Rêgo C, Santos-Silva A, Belo L.
    Pediatric Research, 82(5): 781-788. 2017
    doi: 10.1038/pr.2017.139

  • Factor V Leiden G1691a and prothrombin G20210A polymorphisms in Georgian arterial thrombosis patients.
    Sopio G, Costa E, Bronze-Rocha E, Santos-Silva A, Giorgi N, Salome G, Nona K, Marina K.
    International Journal of Advanced Research, 5: 1171-1175. 2017

  • Impact of weight loss on inflammation and red blood cell biomarkers after laparoscopic gastric banding surgery.
    Coimbra S, Ferreira C, Belo L, Rocha-Pereira P, Catarino A, Monteiro L, Catarino C, Santos-Silva A.
    Journal of Investigative Medicine, 0 : 1-5. 2017

  • Innate IFN-gamma-Producing Cells Developing in the Absence of IL-2 Receptor Common gamma-Chain.
    Resende, M., Cardoso, M. S., Ribeiro, A. R., Florido, M., Borges, M., Castro, A. G., Appelberg, R.
    J Immunol, 199(4), 1429-1439. 2017
    doi: 10.4049/jimmunol.1601701

  • Targeted macrophages delivery of rifampicin-loaded lipid nanoparticles to improve tuberculosis treatment.
    Vieira, A. C., Magalhaes, J., Rocha, S., Cardoso, M. S., Santos, S. G., Borges, M., Reis, S.
    Nanomedicine (Lond), 12(24), 2721-2736. 2017
    doi: 10.2217/nnm-2017-0248

  • Consensus strategy in genes prioritization and combined bioinformatics analysis for preeclampsia pathogenesis.
    Tejera E, Cruz-Monteagudo M, Burgos G, Sánchez ME, Sánchez-Rodríguez A, Pérez-Castillo Y, Borges F, Cordeiro MNDS, Paz-Y-Miño C, Rebelo I.
    BMC Med Genomics. Aug 8;10(1):50. 2017
    doi: 10.1186/s12920-017-0286-x. PMID: 28789679

  • The endocannabinoid system expression in the female reproductive tract is modulated by estrogen.
    Maia J, Almada M, Silva A, Correia-da-Silva G, Teixeira N, Sá SI, Fonseca BM.
    J Steroid Biochem Mol Biol. S0960-0760(17)30188-7. 2017
    doi: 10.1016/j.jsbmb.2017.07.023

  • The synthetic cannabinoid WIN-55,212-55,212 induced-apoptosis in cytotrophoblasts cells by a mechanism dependent on CB1 receptor.
    Almada M, Costa L, Fonseca BM, Amaral C, Teixeira N, Correia-da-Silva G
    Toxicology 385 67–73. 2017
    doi: 10.1016/j.tox.2017.04.013

  • Dynamics of progesterone and estrogen receptor alpha in the ventromedial hypothalamus.
    Sá S, Fonseca BM.
    J Endocrinol. 233(2):197-207. 2017
    doi: 10.1530/JOE-16-0663

  • Anandamide oxidative metabolism-induced endoplasmic reticulum stress and apoptosis.
    Almada M, Fonseca BM, Amaral C, Diniz-da-Costa M, Correia-da-Silva G, Teixeira NA.
    Apoptosis 22(6):816-826. 2017
    doi: 10.1007/s10495-017-1356-4

  • The role of Soybean extracts and isoflavones in hormone-dependent breast cancer: aromatase activity and biological effects.
    Cristina Amaral, Maria Regina T. Toloi, Luis Daniel Vasconcelos, Maria José V. Fonseca, Georgina Correia-da-Silva, Natércia Teixeira.
    Food & Function, 8(9): 3064-3074. 2017
    doi: 10.1039/C7FO00205J

  • Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells.
    Cristina Amaral, Carla L. Varela, João Maurício, Filipa Sobral, Saul C. Costa, Fernanda M.F. Roleira, Elisiário Tavares da Silva, Georgina Correia-da-Silva, Natércia Teixeira
    Journal of Steroid Biochemistry and Molecular Biology, 171: 218-228. 2017
    doi: 10.1016/j.jsbmb.2017.04.002




2016
  • Genetic variants at the Wnt/β-catenin and oestrogen receptor signalling pathways are associated with low bone mineral density in dancers.
    Tânia Amorim, Cecília Durães, José Maia, José Carlos Machado, Luísa Nogueira, Nuno Adubeiro, Andreas D. Flouris, George S. Metsios, Franklim Marques, Matthew Wyon & Yiannis Koutedakis.
    Bone Abstracts 5 P238 | (43rd Annual European Calcified Tissue Society Congress, Rome, Italy. 14 May 2016 - 17 May 2016. European Calcified Tissue Society). 2016
    doi: 10.1530/boneabs.5.P238.

  • Induction and subcellular redistribution of progesterone receptor A and B by tamoxifen in the hypothalamic ventromedial neurons of young adult female Wistar rats.
    Sá SI, Fonseca BM, Teixeira N, Madeira MD.
    Mol Cell Endocrinol. 420:1-10. 2016
    doi: 10.1016/j.mce.2015.11.015

  • A decrease in inflammation associates with an improvement in iron status in obese children and adolescentes.
    Coimbra S, Catarino C, Nascimento H, Alves AI, Medeiros AF, Bronze-da-Rocha E, Costa E, Rocha-Pereira P, Aires L, Seabra A, Mota J, Mansilha HF, Rêgo C, Santos-Silva A, Belo L.
    Medicine, 95 (10): 23. 2016
    doi: 10.1097/MD.0000000000002371

  • Under online-hemodiafiltration: three-year follow-up study.
    Sousa-Martins P, Moura A, Madureira J, Alija P, Oliveira JG, Lopez M, Filgueiras M, Amado L, Sameiro-Faria M, Miranda V, Mesquita E, Teixeira L, Santos-Silva A, Lobato L, Costa E.
    Medicine, 95 (10): 25. 2016
    doi: 10.1097/MD.0000000000002371

  • Renal function, inflamation and psoriasis vulgaris.
    Coimbra S, Oliveira H, Catarino C, Rocha-Pereira P, Figueiredo A, Santos-Silva A.
    Nephrology Dialysis Transplantation, 31 (Supplement 1): i200–i213. 2016
    doi: 10.1093/ndt/gfw167.39

  • Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by recombinant human erythropoietin in the rat.
    Ribeiro S, Garrido P, Fernandes J, Vala H, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva
    A. Nephrology Dialysis Transplantation, 31 (Supplement 1): i115. 2016
    doi: 10.1093/ndt/gfw158

  • Liver iron is a major regulator of hepcidin gene expression via bmp/smad pathway in a rat model of chronic renal failure under treatment with high Rhuepo doses.
    Ribeiro S, Garrido P, Fernandes J, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.
    Nephrology Dialysis Transplantation, 31 (Supplement 1): i194. 2016

  • IgG mediated opsonization mechanism according to the underlying protein deficiency in hereditary spherocytosis: testing a hypothesiss.
    Rocha S, Cleto E, Barbot J, Ferreira F, Quintanilha A, Belo L, Lima M, Bronze-da-Rocha E, Santos-Silva A.
    Haematologica, 101(s1):607. abstract n. 1469. 2016

  • Prevalence of frailty in end-stage renal disease patients and its association with Clinical and biochemical markers.
    Poveda V, Filgueiras M, Miranda V, Santos-Silva A, Paul C, Costa E.
    European Geriatric Medicine, 7S1: S72-S73. 2016

  • Prevalence and predictors of cognitive impairment among older adults across Europe based on SHARE database.
    Lourenço J, Serrano A, Santos-Silva A, Gomes M, Afonso C, Freita P, Paul C, Costa E.
    European Geriatric Medicine, 7S1: S55. 2016

  • Interleucina 31 y pruritus associado a los linfomas cutaneos de células T.
    Abreu M, Castro M, Cabral R, Fernandes I, Leander M, Santos Ana H, Fonseca S, Miranda M, Lau C, Freitas I, Coimbra S, Santos-Silva A, Lima M.
    Haematologica, 101 (s4): 230 (ISSN 0390-6078). 2016

  • Systemic inflammation and pro-inflammatory IL17 signalling persists at the end of therapy in patients with metabolic syndrome and psoriasis, reducing the length of remission.
    Coimbra S, Oliveira H, Neuparth MJ, Proença JB, Figueiredo A, Rocha-Pereira P, Santos-Silva A.
    British Journal of Dermatology; 174 (2): 414-6 . 2016
    doi: 10.1111/bjd.14013

  • Iron therapy in chronic kidney disease: Recent changes, benefits and risks.
    Ribeiro S, Belo L, Reis F, Santos-Silva A.
    Blood Reviews, 30: 65-72. FI 5.565. 2016

  • Predictors of difficulty in medication intake in Europe: a cross-country analysis based on SHARE.
    Figueiredo D, Teixeira L, Poveda V, Paúl C, Santos-Silva A, Costa E.
    Aging and Disease, 7 (3) : 246-253. 2016

  • Effects of 6-month soccer and traditional physical activity programmes on body composition, cardiometabolic risk factors, inflammatory, oxidative stress markers and cardiorespiratory fitness in obese boys.
    Seabra A, Katzmarzyk P, Carvalho MJ, Seabra AC, Coelho e Silva M, Abreu S, Vale S, Nascimento H, Belo L, Torres S, Santos-Silva A, Rêgo C, Malina R.
    Journal of Sports Sciences, 18 : 1-8. IF 2.246. 2016

  • Renal risk-benefit determinants of recombinant human erythropoietin therapy in the remnant kidney rat model – hypertension, anemia, inflammation and drug dose.
    Ribeiro S, Garrido P, Fernandes J, Vala H, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.
    Clinical and Experimental Pharmacology and Physiology, 43 : 343-354. IF 2.372. 2016

  • Risk Factors for Mortality in End-Stage Kidney Disease Patients Under Online-Hemodiafiltration: Three-Year Follow-Up Study.
    Sousa-Martins P, Moura A, Madureira J, Alija P, Oliveira JG, Lopez M, Filgueiras M, Amado L, Sameiro-Faria M, Miranda V, Mesquita E, Teixeira L, Poveda V, Lobato L, Santos-Silva A, Costa E.
    Biomarkers, 21: 544-550. IF 2.215. 2016

  • Liver iron is a major regulator of hepcidin gene expression via BMP/SMAD pathway in a rat model of chronic renal failure under treatment with high rHuEPO doses.
    Ribeiro S, Garrido P, Fernandes J, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.
    BioFactors, 42: 296-306. 2016

  • Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by rHuEPO in the rat.
    Ribeiro S, Garrido P, Fernandes J, Vala H, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.
    Life Sciences, 151 : 147-156. IF 2.702. 2016

  • Impact of a school-based intervention protocol – ACORDA project - in adipokines in an overweight and obese pediatric population.
    Nascimento H, Alves AI, Medeiros AF, Coimbra S, Catarino C, Bronze-da-Rocha E, Costa E, Rocha-Pereira P, Aires L, Seabra A, Mota J, Mansilha HF, Rêgo C, Santos-Silva A, Belo L.
    Pediatric Exercise Scienc, 28 : 407-416. 2016

  • Pathological and molecular mechanisms underlying resistance to recombinant human erythropoietin therapy in the remnant kidney rat model of chronic kidney disease associated anemia.
    Ribeiro S, Garrido P, Fernandes J, Vala H, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.
    Biochimie, 125 : 150-162. 2016

  • The triad psoriasis-obesity-adipokine The triad psoriasis-obesity-adipokine profile.
    Coimbra S, Catarino C, Santos-Silva A.
    Journal of the European Academy of Dermatology & Venereology, 30: 1876-1885. 2016

  • Adipokine Gene Single-Nucleotide Polymorphisms in Portuguese Obese Adolescents: Associations with Plasma Concentrations of Adiponectin, Resistin, IL-6, IL-1β, and TNF-α.
    Nascimento H, Vieira E, Coimbra S, Catarino C, Costa E, Bronze-da-Rocha E, Rocha-Pereira P, Carvalho M, Ferreira H, Rêgo C, Santos R, Santos-Silva A, Belo L.
    Childhood Obesity, 12: 300-313. 2016

  • Recombinant human erythropoietin-induced erythropoiesis regulates hepcidin expression over iron status in the rat.
    Ribeiro S, Garrido P, Fernandes J, Rocha S, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.
    Blood Cells, Molecules and Diseases, 59 : 63–70. 2016

  • Polymorphisms of the ELANE gene promoter region in end-stage chronic kidney disease patients.
    Fernandes R, Freitas B, Miranda V, Costa E, Santos-Silva A, Bronze-da-Rocha E.
    Genes, 7, 17. 2016
    doi: 10.3390/genes7050017

  • Psoriasis treatment: targeting the IL-23/Th17 axis. In: Psoriasis: Epidemiology, Diagnosis and Management Strategies.
    Coimbra S, Brandão-Proença J, Figueiredo A, Santos-Silva A.
    Editor: Wilma Lambert. Nova Science Publishers, NY. 2016
    ISBN: 978-1-63485-649-2.
    e-Book, ISBN: 978-1-63485-670-6

  • Obesity-related pathways to Chronic Kidney Disease.
    Belo L, Ribeiro S, Sameiro-Faria M, Miranda V, Santos-Silva A. ARC
    Journal of Nephrology, 1 (1): 1-4. 2016

  • Different hydroxyapatite magnetic nanoparticles for medical imaging: Its effects on hemostatic, hemolytic activity and cellular cytotoxicity.
    Laranjeira MS, Moçob AA, Ferreira J , Coimbra S, Costa E, Santos-Silva A, Ferreira PJ, Monteiro FJ.
    Colloids and Surfaces B: Biointerfaces, 146:363-374. 2016

  • Long term performance evaluation of small-diameter vascular grafts based on polyvinyl alcohol hydrogel and dextran and MSCs-based therapies using the ovine pre-clinical animal model.
    Alexandre N, Amorim I, Caseiro AR, Pereira T, Alvites R, Rêma A, Gonçalves A, Valadares G, Costa E, Santos-Silva A, Rodrigues M, Lopes MA, Almeida A, Santos JD, Maurício AC, Luís AL.
    International Journal of Pharmaceutics, 513:332-346. 2016

  • Exercise intervention and cardiovascular risk factors in obese children. Comparison between obese youngsters taking part of a physical activity school-based program with and without individualized diet counseling: The ACORDA Project.
    Aires L, Silva G, Martins C, Marques E, Lagoa MJ, Ribeiro JC, Rêgo C, Nascimento H, Rocha-Pereira P, Santos-Silva A, Belo L, Mota J.
    Annals of Human Biology; 43:183–190. 2016

  • Biomarkers in bladder cancer: a metabolomic approach using in vitro and ex vivo model systems.
    Rodrigues D, Jerónimo C, Henrique R, Belo L, Bastos ML, de Pinho PG, Carvalho M
    International Journal of Cancer; 139:256–268. 2016

  • Scaling up health knowledge at European level requires sharing integrated data: an approach for collection of database specification.
    Menditto E, Bolufer De Gea A, Cahir C, Marengoni A, Riegler S, Fico G, Costa E, Monaco A, Pecorelli S, Pani L, Prados-Torres A.
    ClinicoEconomics and Outcomes Research, n. 8, p. 253-265. 2016

  • Strategies to improve medication adherence in older persons: Consensus Statement from the Senior Italia Federanziani Advisory Board.
    Marengoni A, Monaco A, Costa E, Cherubini A, Prados-Torres A, Muth C, Melis RJF, Pasina L, van der Cammen TJM, Palmer K, Pecorelli S, Onder G.
    Drugs & Aging, n. 33, p. 1-7. 2016.

  • The endocannabinoid anandamide impairs in vitro decidualization of human cells.
    Almada M, Amaral C, Diniz-da-Costa M, Correia-da-Silva G, Teixeira NA, Fonseca BM.
    Reproduction. 152(4):351-61. 2016
    doi: 10.1530/REP-16-0364

  • Exploring new chemical functionalities to improve aromatase inhibition of steroids.
    Varela CL, Amaral C, Correia-da-Silva G, Costa SC, Carvalho RA, Costa G, Alcaro S, Teixeira NA, Tavares-da-Silva EJ, Roleira FM.
    Bioorg Med Chem. Jun 15;24(12):2823-31. 2016
    doi: 10.1016/j.bmc.2016.04.056

  • Unravelling exemestane: From biology to clinical prospects.
    Sobral AF, Amaral C, Correia-da-Silva G, Teixeira N.
    Journal Steroid Biochem Mol Biol. Oct;163:1-11. 2016
    doi: 10.1016/j.jsbmb.2016.03.019

  • Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release.
    Almada M, Cunha S, Fonseca BM, Amaral C, Piscitelli F, Di Marzo V, Correia-da-Silva G, Teixeira N.
    Biofactors. May;42(3):277-86. 2016
    doi: 10.1002/biof.1270

  • Cannabinoid-induced autophagy: Protective or death role?
    Costa L, Amaral C, Teixeira N, Correia-da-Silva G, Fonseca BM.
    Prostaglandins Other Lipid Mediat. Jan;122:54-63. 2016
    doi: 10.1016/j.prostaglandins.2015.12.006

  • The endocannabinoid 2-arachidonoylglycerol dysregulates the synthesis of proteins by the human syncytiotrophoblast.
    Costa MA, Fonseca BM, Mendes A, Braga J, Teixeira NA, Correia-da-Silva G.
    Biochim Biophys Acta. Mar;1861(3):205-12. 2016
    doi: 10.1016/j.bbalip.2015.12.008

  • Coffee: A Dietary Intervention on Type 2 Diabetes?
    Casal S, Rebelo I.
    Curr Med Chem. Oct 3. 2016 [Epub ahead of print]

  • Efficient and biologically relevant consensus strategy for Parkinson's disease gene prioritization.
    Cruz-Monteagudo M, Borges F, Paz-Y-Miño C, Cordeiro MN, Rebelo I, Perez-Castillo Y, Helguera AM, Sánchez-Rodríguez A, Tejera E.
    BMC Med Genomics. Mar 9;9:12. 2016
    doi: 10.1186/s12920-016-0173-x.




2015
  • Prevalence of low bone mineral density in female dancers.
    Amorim T, Wyon M, Maia J, Machado JC, Marques F, Metsios GS, Flouris AD, Koutedakis Y.
    Sports Med. Feb;45(2):257-68. 2015
    doi: 10.1007/s40279-014-0268-5. Review. (IF-7,074)

  • Cell free DNA in Portuguese preeclamptic pregnancy.
    Catarino C, Coimbra S, Gomes D, Belo L, Rocha S, Bicho M, Rebelo I, Santos-Silva A.
    Pregnancy Hypertension: an International Journal of Women's Cardiovascular Health. 2015, 5 (1): 70-71.

  • Longitudinal results in a school-based intervention program for obese children.
    Aires L, Alves AI, Silva G, Medeiros AF, Nascimento H, Catarino C, Rocha-Pereira P, Martins C, Ribeiro JC, Santos-Silva A, Mota J, Belo L.
    Appetite. 2015, 89 : 323.

  • Recombinant human erythropoietin-induced erythropoiesis regulates hepcidin expression over iron in a rat model.
    Ribeiro S, Garrido P, Fernandes J, Rocha S, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva
    A. Haematologica, 2015, 100 (Supplement 1): 129.

  • Liver iron regulates hepcidin expression. Studies in a rat model of chronic renal failure under recombinant human erythropoietin therapy.
    Ribeiro S, Garrido P, Fernandes J, Rocha S, Nunes S, Rocha-Pereira P, Costa E, Belo L, Reis F, Santos-Silva A.
    The FEBS Journal, 2015, 282 (1) : 98.

  • Recombinant human erythropoietin treatment in a rat model of nephrectomy.
    Ribeiro S, Vala H, Garrido P, Fernandes J, Costa E, Belo L, Reis F, Santos-Silva A.
    Virchows Archive, 2015, 467 (Supplement 1): S1-S279.

  • Exemestane metabolites suppress growth of estrogen receptor-positive breast cancer cells by inducing apoptosis and autophagy: A comparative study with Exemestane.
    Amaral C, Lopes A, Varela CL, da Silva ET, Roleira FM, Correia-da-Silva G, Teixeira N.
    Int J Biochem Cell Biol. 69:183-95. doi: 10.1016/j.biocel.2015.10.024, 2015

  • Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator.
    Almada M, Piscitelli F, Fonseca BM, Di Marzo V, Correia-da-Silva G, Teixeira N.
    Biochim Biophys Acta. 1851(11):1473-81. doi: 10.1016/j.bbalip.2015.08.011, 2015

  • The endocannabinoid anandamide affects the synthesis of human syncytiotrophoblast-related proteins.
    Costa MA, Fonseca BM, Mendes A, Braga J, Teixeira NA, Correia da Silva G.
    Cell Tissue Res. 362(2):441-6. doi: 10.1007/s00441-015-2236-2, 2015

  • Estrogen receptors α and β have different roles in the induction and trafficking of progesterone receptors in hypothalamic ventromedial neurons.
    Sá SI, Fonseca BM, Teixeira N, Madeira MD.
    FEBS J. 282(6):1126-36. doi: 10.1111/febs.13207, 2015

  • Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a human keratinocyte cell line.
    Almeida IF, Pinto AS, Monteiro C, Monteiro H, Belo L, Fernandes J, Bento AR, Duarte TL, Garrido J, Bahia MF, Sousa Lobo JM, Costa PC.
    Journal of Photochemistry and Photobiology B: Biology 144C:28–34, 2015

  • Adiponectin, leptin and chemerin in elderly patients with type 2 diabetes mellitus. A close linkage with obesity and length of the disease.
    Coimbra S, Proença JB, Santos-Silva A, and Neuparth MJ.
    Artigo publicado no “Biomed Res Int. 2014” foi seleccionado para destaque no World Biomedical Frontiers, pela sua inovação e potencial impacto Diabetes and Obesity do World Biomedical Frontiers (ISSN: 2328-0166), 2015.

  • Self-reported medication adherence in patients with end-stage kidney disease under online-hemodiafiltration.
    Amado L, Ferreira N, Miranda V, Meireles P, Povera V, Fazendeiro-Matos J, Teixeira L, Paúl C, Santos-Silva A, Costa E.
    Journal of Renal Care. 41(4):231-8. doi: 10.1111/jorc.12127, 2015

  • Peroxiredoxin 2, Glutathione Peroxidase and Catalase in the cytosol and membrane of erythrocytes under H2O2-induced oxidative stress.
    Rocha S, Gomes D, Lima M, Bronze-da-Rocha E, Santos-Silva A.
    Free Radical Research. 49(8) : 990-1003. doi: 10.3109/10715762.2015.1028402, 2015

  • Resistance to recombinant human erythropoietin therapy in a rat model of chronic kidney disease associated anemia.
    Garrido P, Ribeiro S, Fernandes J, Vala H, Rocha-Pereira P, Bronze-da-Rocha E, Belo L, Costa E, Santos-Silva A, Reis F.
    International Journal of Molecular Science. 1, 7(1). pii: E28. doi: 10.3390/ijms17010028, 2015

  • Protective effect of C. sativa leaf extract against UV mediated-DNA damage in a human keratinocyte cell line.
    Almeida IF, Pinto AS, Monteiro C, Monteiro H, Belo L, Fernandes J, Bento AR, Duarte TL, Garrido J, Bahia MF, Sousa Lobo JM, Costa PC.
    Journal of Photochemistry and Photobiology B: Biology. 144C:28–34, 2015

  • Performance of in silico tools for evaluating UGT1A1 missense variants.
    Rodrigues C, Santos-Silva, A, Costa, E, Bronze-da-Rocha E.
    Human Mutation 36: 1215-1225, 2015.

  • The biochemical interplay between MCP1 and ATR.
    Bronze-da-Rocha E, Lin C-M, Aladjem MI.
    International Journal of Biotech Trends and Technology 12: 1-6, 2015.

  • Exercise intervention and cardiovascular risk factors in obese children. Comparison between obese youngsters taking part of a physical activity school-based program with and without individualized diet counseling: The ACORDA Project.
    Aires L, Silva G, Martins C, Marques E, Lagoa MJ, Ribeiro JC, Rego C, Costa P, Nascimento H, Santos-Silva A, Belo L, Mota JA.
    In a special issue "The Effect of Early Life Factors and Early Interventions on Childhood Overweight and Obesity" of Annals of Human Biology, online 1–8, 2015

  • Interventional Tools to Improve Prescription and Adherence to Medical Plans.
    Costa E, Giardini A, Prados-Torres A, Cahir C, Marengoni A.
    Biomed Res Int. 2015:602078, 2015

  • Interventional tools to improve medication adherence: review of literature.
    Costa E, Giardini A, Savin M, Menditto E, Lehane E, Laosa O, Pecorelli S, Monaco A, Marengoni A.
    Patient Prefer Adherence. 14;9:1303-14., 2015

  • Effect of Aging in the Perception of Health-Related Quality of Life in End-Stage Renal Disease Patients under Online-Hemodiafiltration.
    Moura A, Madureira J, Alija P, Fernandes JC, Oliveira JG, Lopez M, Filgueiras M, Amado L, Sameiro-Faria M, Miranda V, Santos-Silva A, Costa E.
    Aging Dis. 6(1): 17–26, 2015

  • Unravelling the relationship between protein sequence and low-complexity regions entropies: Interactome implications.
    F Martins, R Gonçalves, J Oliveira, M Cruz-Monteagudo, J M Nieto-Villar, C Paz-Y-Miño, I Rebelo, E Tejera
    Journal of Theoretical Biology. 7,doi: 10.1016/j.jtbi.2015.06.049, 2015

  • Biochemical and cellular changes in leukocyte-depleted red blood cell units stored for transfusion.
    Nogueira D, Rocha S, Abreu E, Costa E, Santos-Silva A.
    Transfusion Medicine and Hemotherapy. 42(1):46-51, 2015

  • TLR4 and TLR9 polymorphisms effect on inflammatory response in end-stage renal disease patients.
    Santos-Martins M, Sameiro-Faria M, Ribeiro S, Rocha-Pereira P, Nascimento H, Reis F, Miranda V, Quintanilha A, Belo L, Beirão I, Santos-Silva A, Bronze-da-Rocha E, Costa E.
    European Journal of Inflammation. 12(3):521-529, 2015

  • Predictors of health-related quality of life perceived by end-stage renal disease patients under online-hemodiafiltration.
    Moura A, Madureira J, Alija P, Fernandes JC, Oliveira JG, Lopez M, Filgueiras M, Amado L, Sameiro-Faria M, Miranda V, Mesquita E, Santos-Silva A, Costa E.
    Quality of Life Research, Qual Life Res. 24(6):1327-35, 2015

  • Bilirubin is independently associated with oxidized LDL levels in young obese patients.
    Nascimento H, Alves AI, Coimbra S, Catarino C, Gomes D, Bronze-da-Rocha E, Costa E, Rocha-Pereira P, Aires L, Mota J, Mansilha HF, Rêgo C, Santos-Silva A, Belo L.
    Diabetology & Metabolic Syndrome. 7:4, 2015

  • In vitro and in vivo evaluation of blood coagulation activation of polyvinyl alcohol hydrogel plus dextran based vascular grafts.
    Alexandre N, Costa E, Coimbra S, Santos-Silva A, Lopes A, Rodrigues M, Santos M, Maurício AC, Santos JD, Luís AL.
    Journal of Biomedical Material Research Part A. J Biomed Mater Res A. 103(4):1366-79, 2015

  • Longitudinal data from a school-based intervention - The ACORDA project (Datos longitudinales de un programa intervención en la escuela - proyecto ACORDA).
    Aires L, Silva G, Alves AI, Medeiros AF, Nascimento H, Magalhães C, Martins C, Rocha Pereira P, Santos-Silva A, Belo L, Mota J.
    RETOS. 28, 222-225, 2015

  • Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.
    Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze-da-Rocha E, Rocha-Pereira P, Belo L, Costa E, Santos-Silva A, Reis F.
    PLOS ONE. 10(4):e0124048, 2015

  • Comparison between CDC and WHO BMI z-score and their relation with metabolic risk markers in Portuguese obese adolescentes.
    Nascimento H, Catarino C, Mendonça D, Oliveira P, Alves AI, Medeiros AF, Rocha-Pereira P, Rêgo C, Ferreira-Mansilha H, Aires L, Mota J, Quintanilha A, Santos-Silva A, Belo L.
    Diabetology & Metabolic Syndrome. 7:32, 2015

  • Hydroxiapatite-based materials of marine origin: a bioactivity and sintering study.
    Piccirillo C, Pullar RC, Costa E, Santos-Silva A, Pintado MME, Castro PML.
    Materials Science and Engineering. C51:309-315, 2015

  • Effects of the olive oil phenol metabolite 3,4-DHPEA-EDAH2 on human erythrocyte oxidative damage.
    Paiva-Martins F, Gonçalves P, Borges JE, Przybylska D, Ibba F, Fernandes J, Santos-Silva A.
    Food & Function. 6(7):2350-2356, 2015

  • The Warburg effect in mycobacterial granulomas is dependent on the recruitment and activation of macrophages by interferon-γ.
    Appelberg R, Moreira D, Barreira-Silva P, Borges M, Silva L, Dinis-Oliveira RJ, Resende M, Correia-Neves M, Jordan MB, Ferreira NC, Abrunhosa AJ, Silvestre R.
    Immunology. 45(4):498-507, 2015

  • Lack of the transcription factor hypoxia-inducible factor (HIF)-1α in macrophages accelerates the necrosis of Mycobacterium avium-induced granulomas.
    Cardoso MS, Silva TM, Resende M, Appelberg R, Borges M.
    Infect Immun. pii:IAI.00144-15, 2015

  • 2-Arachidonoylglycerol impairs human cytotrophoblast cells syncytialization: influence of endocannabinoid signalling in placental development.
    Costa MA, Keating E, Fonseca BM, Teixeira NA, Correia-da-Silva G.
    Mol Cell Endocrinol. 5;399:386-94, 2015

  • The psychoactive compound of Cannabis sativa, Δ9-tetrahydrocannabinol (THC) inhibits the human trophoblast cell turnover.
    Costa MA, Fonseca BM, Marques F, Teixeira NA, Correia-da-Silva G.
    Toxicology. 9;334:94-103, 2015

  • Anandamide restricts uterine stromal differentiation and is critical for complete decidualization.
    Fonseca BM, Correia-da-Silva G, Teixeira NA.
    Mol Cell Endocrinol. 15;411:167-76, 2015

  • Lipidomic approach towards deciphering anandamide effects in rat decidual cell.
    Almada M, Domingues MR, Dória ML, Fonseca BM, Teixeira NA, Correia-da-Silva G.
    J Cell Physiol. 230(7):1549-57, 2015

  • The endocannabinoid anandamide induces apoptosis in cytotrophoblast cells: involvement of both mitochondrial and death receptor pathways.
    Costa MA, Fonseca BM, Teixeira NA, Correia-da-Silva G.
    Placenta. 36(1):69-76, 2015

  • Translating endoplasmic reticulum biology into the clinic: a role for ER-targeted natural products?
    Pereira DM, Valentão P, Correia-da-Silva G, Teixeira N, Andrade PB.
    Nat Prod Rep. 29;32(5):705-22, 2015




2014
  • The positive effect of moderate walking exercise on chemerin levels in Portuguese patients with type 2 diabetes mellitus.
    Neuparth MJ, Proença JB, Santos-Silva A, Coimbra S.
    Journal of Investigative Medicine. 62 (2) : 350-353, 2014

  • Circulating cell-free DNA levels in Portuguese patients with psoriasis vulgaris according to severity and therapy.
    Coimbra S, Catarino C, Costa E, Oliveira H, Figueiredo A, Rocha-Pereira P, Santos-Silva A.
    British Journal of Dermatology. 170:939-942, 2014

  • Aging is associated with impaired renal function, INF-gamma induced inflammation and with alterations in iron regulatory proteins gene expression.
    Costa E, Fernandes J, Ribeiro S, Sereno J, Garrido P, Rocha-Pereira P, Coimbra S, Catarino C, Belo L, Bronze-da-Rocha E, Alves R, Reis F, Santos-Silva A.
    Aging and Disease. 5(6):356-365, 2014

  • Biocompatibility and hemocompatibility of polyvinyl alcohol hydrogel used for vascular grafting – in vitro and in vivo studies.
    Alexandre N, Ribeiro J, Gärtner A, Pereira T, Amorim I, Fragoso J, Lopes A, Rodrigues M, Fernandes J, Costa E, Santos-Silva A, Santos JD, Maurício AC, Luís AL.
    Journal of Biomedical Materials Research Part A. 102A : 4262–4275, 2014

  • Macroglobulinémia de Waldenström – uma revisão.
    Coimbra C, Neves R, Lima M, Belo L, Santos-Silva A.
    Revista da Associação Médica Brasileira, 60(5):488-497, 2014

  • Biomarkers of psoriasis severity and therapy monitoring.
    Coimbra S and Santos-Silva A.
    World Journal of Dermatology, 3(2):15-27, 2014

  • Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat – focus on serum, urine, gene and protein renal expression biomarkers.
    Sereno J, Nunes S, Rodrigues-Santos P, Vala H, Rocha-Pereira P, Fernandes J, Santos-Silva A, Teixeira F, Reis F.
    BioMed Research International, Special issue on "Emerging Biomarkers in Renal Damage" 2014:576929, 2014

  • The effect of olive leaf supplementation on the constituents of blood and oxidative stability of red blood cells.
    Paiva-Martins F, Barbosa S, Silva M, Monteiro D, Pinheiro V, Mourão JL, Fernandes J, Rocha S, Belo L, Santos-Silva A.
    Journal of Functional Foods, 9:271-279, 2014

  • Body fat percentage is a major determinant of total bilirubin independently of UGT1A1*28 polymorphism in young obese.
    Belo L, Nascimento H, Kohlova M, Bronze-da-Rocha E, Fernandes J, Costa E, Catarino C, Aires L, Mansilha HF, Rocha-Pereira P, Quintanilha A, Rêgo C, Santos-Silva A.
    PLOS ONE, 9(6):e98467, 1-9, 2014

  • Adiponectin and markers of metabolic syndrome in obese children and adolescentes: impact of 8 month regular physical exercise program.
    Nascimento H, Costa E, Rocha S, Lucena C, Rocha-Pereira P, Rêgo C, Mansilha HF, Quintanilha A, Aires L, Mota J, Santos-Silva A Belo L.
    Pediatric Research, 76(2):159-165, 2014

  • Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model – focus on mechanisms and biomarkers of kidney fibrosis and proliferation.
    Sereno J, Rodrigues-Santos P, Vala H, Rocha-Pereira P, Alves R, Fernandes J, Santos-Silva A, Carvalho E, Teixeira F, Reis F.
    Special issue: Renal Toxicology—Epidemiology and Mechanisms in International Journal of Molecular Sciences, 15(5):8979-89, 2014

  • Effect of aging in the perception of health-related quality of life in end-stage renal disease patients under online-hemodiafiltration.
    Moura A, Madureira J, Alija P, Fernandes JC, Oliveira JG, Lopez M, Filgueiras M, Amado L, Faria MS, Miranda V, Vieira M, Santos-Silva A, Costa E.
    Aging and Disease, 6(1):17-26, 2014

  • Haptoglobin 2-2 phenotype is associated with decreased serum iron levels in endstage renal disease patients resistant to rhEPO therapy.
    Martins F, Catarino C, Rocha-Pereira P, Reis F, Sameiro-Faria M, Miranda V, Belo L, Bronze-da-Rocha E, Costa E, Santos-Silva A.
    British Journal of Biomedical Science. 71(2):79-81, 2014

  • Adiponectin, leptin, and chemerin in elderly patients with type 2 Diabetes Mellitus: a close linkage with obesity and length of the disease.
    Coimbra S, Proença JB, Santos-Silva A, Neupart MJ.
    BioMed Research International, Special issue on “Aging and Cardiovascular Disease”. Vol. 2014 Article ID 701915, 8 pages, 2014

  • Brodalumab: an evidence-based review of its potential in the treatment of moderate-to-severe psoriasis.
    Coimbra S, Figueiredo A, Santos-Silva A.
    Core Evidence. 9: 89–97, 2014

  • Potential Cardiovascular Risk Protection of Bilirubin in End-Stage Renal Disease Patients under Hemodialysis.
    Sameiro-Faria M, Kohlova M, Ribeiro S, Rocha-Pereira P, Teixeira L, Nascimento H, Reis F, Miranda V, Bronze-da-Rocha E, Quintanilha A, Belo L, Costa E, Santos-Silva A.
    BioMed Research International, vol. 2014, Article ID 175286, 9 pages, doi:10.1155/2014/175286, 2014

  • Iron as the key modulator of hepcidin expression in erythroid antibody-mediated hypoplasia.
    Fernandes JC, Garrido P, Ribeiro S, Rocha-Pereira P, Bronze-da-Rocha E, Belo L, Costa E, Reis F, Santos-Silva A.
    BioMed Research International, vol. 2014, Article ID 421304, 10 pages, 2014

  • TLR4 and TLR9 polymorphisms effect on inflammatory response in end-stage renal disease patients.
    Santos-Martins M, Sameiro-Faria M, Ribeiro S, Rocha-Pereira P, Nascimento H, Reis F, Miranda V, Quintanilha A, Belo L, Beirão I, Santos-Silva A, Bronze-da-Rocha E, Costa E.
    European Journal of Inflammation, 12 (3) : 521-529, 2014

  • Atypical phenotype in two patients with LAMA2 mutations.
    Marques J, Duarte ST, Costa S, Jacinto S, Oliveira J, Oliveira ME, Santos R, Bronze-da-Rocha E, Silvestre AR, Calado E, Evangelista T.
    Neuromuscular Disorders, 24:419-424, 2014

  • New variants, challenges and pitfalls in DMD genotyping: implications in diagnosis, prognosis and therapy.
    Santos R, Gonçalves A, Oliveira J, Vieira E, Vieira JP, Evangelista T, Moreno T, Santos M, I. Fineza I, Bronze-da-Rocha E.
    Journal of Human Genetics 59: 454-464, 2014

  • MicroRNAs expression profiles in cardivascular diseases.
    Bronze-da-Rocha E.
    BioMed Research International, Article ID 985408-85431, 2014

  • Reviewing Large LAMA2 Deletions and Duplications in Congenital Muscular Dystrophy Patients.
    Oliveira J, Gonçalves A, Márcia E. Oliveira ME, Isabel Fineza I, Rita C.M. Pavanello RCM, Vainzof M, Bronze-da-Rocha E, Santos R, Sousa M.
    Journal of Neuromuscular Diseases. 1:169-179, 2014

  • Inflammatory markers of cardiovascular disease risk in Portuguese psoriatic patients – relation with NB-UVB and PUVA therapy.
    Coimbra S, Oliveira H, Neuparth MJ, Figueiredo A, Rocha-Pereira P, Santos-Silva A.
    International Journal of Dermatology, 53(3):393-6, 2014

  • Effect of bariatric surgery on weight loss, inflammation, iron metabolism, and lipid profile.
    Santos J, Salgado P, Santos C, Mendes P, Saavedra J, Baldaque P, Monteiro L, Costa E.
    Scandinavian Journal of Surgery, 103:21–25, 2014

  • Ryanodine myopathies without central cores--clinical, histopathologic, and genetic description of three cases.
    Rocha J, Taipa R, Melo Pires M, Oliveira J, Santos R, Santos M.
    Pediatric Neurology. 51(2):275-8, 2014

  • Variobox: automatic detection and annotation of human genetic variants.
    Gaspar P, Lopes P, Oliveira J, Santos R, Dalgleish R, Oliveira JL.
    Human Mutation. 35(2):202-7, 2014

  • Membranoproliferative glomerulonephritis and x-linked agammaglobulinemia: an uncommon association.
    Lavrador V, Correia F, Sampaio R, Cândido C, Sameiro-Faria M, Marques L, Mota C.
    Case Reports in Pediatrics. 2014:480947, 2014

  • BK virus nephropathy complicated with meningoencephalitis after kidney transplantation.
    Rocha A, Faria S, Costa T, Marques L, Freitas C, Mota C.
    Pediatric Transplantion. 18(2):E48-51, 2014

  • Predictive factors of graft censored failure in pediatric kidney transplants.
    Rocha A, Rocha L, Malheiro J, Azevedo P, Tavares T, Faria MS, Mota C, Dias L, Henriques AC.
    Transplantion Proceedings, 46:1723-26, 2014

  • Infections Following Kidney Transplant in Children: a single-center study.
    Fernandes A, Rocha L, Costa T, Matos P, Faria MS, Marques L, Mota C, Henriques AC.
    Open Journal of Nephrology. 4: 117-124, 2014

  • Rat spontaneous foetal resorption: altered alpha 2-macroglobulin levels and uNK cell number.
    Fonseca BM, Almada M, Costa MA, Teixeira NA, Correia-da-Silva G.
    Histochemistry and Cell Biology 142: 6, 693-701, 2014

  • Transient receptor potential vanilloid 1 is expressed in human cytotrophoblasts: Induction of cell apoptosis and impairment of syncytialization.
    Costa MA, Fonseca BM, Keating E, Teixeira NA, Correia-da-Silva G.
    Int J Biochem Cell Biol. 57:177-85, 2014

  • Exemestane metabolites: Synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line.
    Varela CL, Amaral C, Tavares da Silva E, Lopes A, Correia-da-Silva G, Carvalho RA, Costa SC, Roleira FM, Teixeira N.
    Eur J Med Chem. 24;87:336-45, 2014

  • Activity of anandamide (AEA) metabolic enzymes in rat placental bed.
    Fonseca BM, Battista N, Correia-da-Silva G, Rapino C, Maccarrone M, Teixeira NA.
    Reprod Toxicol. 1;49C:74-77, 2014

  • 2- arachidonoylglycerol effects in cytotrophoblasts: metabolic enzymes expression and apoptosis in BeWo cells.
    Costa MA, Fonseca BM, Keating E, Teixeira NA, Correia-da-Silva G.
    Reproduction. 3;147(3):301-11, 2014

  • GC-MS lipidomic profiling of the echinoderm Marthasterias glacialis and screening for activity against human cancer and non-cancer cell lines.
    Pereira DM, Correia-da-Silva G, Valentão P, Teixeira N, Andrade PB.
    Comb Chem High Throughput Screen. 17(5):450-7, 2014

  • Anti-inflammatory effect of unsaturated fatty acids and Ergosta-7,22-dien-3-ol from Marthasterias glacialis: prevention of CHOP-mediated ER-stress and NF-κB activation.
    Pereira DM, Correia-da-Silva G, Valentão P, Teixeira N, Andrade PB.
    PLoS One. 13;9(2):e88341, 2014

  • Insights into the synthesis of steroidal a-ring olefins.
    Carla L. Varela, Fernanda M. F. Roleira, Saul C. Costa, Alexandra S. C. T. Pinto, Ana I. O. S. Martins, Rui A. Carvalho, Natércia Teixeira, Georgina Correia-da-Silva, Elisiário J. Tavares-da-Silva.
    Helvetica Chimica Acta 97, 39-46, 2014

  • Protein sequence revisited. Relationship with fractal 3D structure, topological and kinetic parameters.
    Tejera E, Nieto-Villar JM, Rebelo I.
    Physica A. 410(15):278-301, 2014

  • Preeclampsia prediction and management.
    Rebelo I, Bernardes J.
    Obstet Gynecol Int. 2014;2014:502081. doi: 10.1155/2014/502081. Epub 2014 Nov 9

  • Glycaemic profile changes by highly active antiretroviral therapy in human immunodeficiency virus-infected patients.
    Duro M, Rebelo I, Barreira S, Sarmento-Castro R, Medeiros R, Almeida C.
    Int J STD AIDS. 2014 Oct 2. pii: 0956462414554814, 2014

  • In women with previous pregnancy hypertension, levels of cardiovascular risk biomarkers may be modulated by haptoglobin polymorphism.
    Matos A, Pereira da Silva A, Clara Bicho M, Afonso C, Areias MJ, Rebelo I, Bicho M.
    Obstet Gynecol Int. 2014:361727, 2014

  • First trimester aneuploidy screening program for preeclampsia prediction in a portuguese obstetric population.
    Teixeira C, Tejera E, Martins H, Pereira AT, Costa-Pereira A, Rebelo I.
    Obstet Gynecol Int. 2014:435037, 2014

  • Biochemical impact of soccer: an analysis of hormonal, muscle damage, and redox markers during the season Appl.
    Silva JR, Rebelo A, Marques F, Pereira L, Seabra A, Ascensão A, Magalhães J.
    Physiol. Nutr. Metab. 39:432–438, 2014

  • Type of vascular access and location in online-hemodiafiltration and its association with patient’s perception of health-related quality of life.
    Moura A, Madureira J, Alija P, Fernandes J, Oliveira JG, Lopez M, Filgueiras M, Amado L, Sameiro-Faria M, Miranda V, Vieira M, Santos-Silva A, Costa E.
    Journal of Vascular Access, 15(3):175-82, 2014

  • Cumulative mitoxantrone-induced haematological and hepatic adverse effects in a sub-chronic in vivo study.
    Rossato LG, Costa VM, Dallegrave E, Arbo M, Dinis-Oliveira RJ, Santos-Silva A, Duarte JA, de Lourdes Bastos M, Palmeira C, Remião F.
    Basic & Clinical Pharmacology & Toxicology, 114, 254–262, 2014




2013
  • Implication of low HDL-c levels in patients with average LDL-c levels: a focus on oxidized LDL, large HDL subpopulation, and adiponectin.
    Mascarenhas-Melo F, Sereno J, Teixeira-Lemos E, Marado D, Palavra F, Pinto R, Rocha-Pereira P, Teixeira F, Reis F.
    Mediators of Inflammation. 2013:612038, 2013

  • Development and validation of a multiplex-PCR assay for X-linked intellectual disability.
    Jorge P, Oliveira B, Marques I, Santos R.
    BMC Medical Genetics. 14:80, 2013

  • The TREAT-NMD Duchenne muscular dystrophy registries: conception, design, and utilization by industry and academia.
    Bladen CL, Rafferty K, Straub V, Monges S, Moresco A, Dawkins H, Roy A, Chamova T, Guergueltcheva V, Korngut L, Campbell C, Dai Y, Bari¨ić N, Kos T, Brabec P, Rahbek J, Lahdetie J, Tuffery-Giraud S, Claustres M, Leturcq F, Ben Yaou R, Walter MC, Schreiber O, Karcagi V, Herczegfalvi A, Viswanathan V, Bayat F, de la Caridad Guerrero Sarmiento I, Ambrosini A, Ceradini F, Kimura E, van den Bergen JC, Rodrigues M, Roxburgh R, Lusakowska A, Oliveira J, Santos R, Neagu E, Butoianu N, Artemieva S, Rasic VM, Posada M, Palau F, Lindvall B, Bloetzer C, Karaduman A, Topaloğlu H, Inal S, Oflazer P, Stringer A, Shatillo AV, Martin AS, Peay H, Flanigan KM, Salgado D, von Rekowski B, Lynn S, Heslop E, Gainotti S, Taruscio D, Kirschner J, Verschuuren J, Bushby K, Béroud C, Lochmüller H.
    Human Mutation. 34(11):1449-1457, 2013

  • A family with 2 different hereditary diseases leading to early cardiac involvement.
    Nzwalo H, Conceição I, Pereira P, Santos R, Evangelista T.
    Journal of Clinical Neuromuscular Diseases. 14(4):204-208, 2013

  • Expanding the MTM1 mutational spectrum: novel variants including the first multi-exonic duplication and development of a locus-specific database.
    Oliveira J, Oliveira ME, Kress W, Taipa R, Pires MM, Hilbert P, Baxter P, Santos M, Buermans H, den Dunnen JT, Santos R.
    European Journal Human Genetics. 21(5):540-549, 2013

  • Partially reversible cardiomyopathy after renal transplant associated with anti-troponin I antibodies.
    Nunes JP, do Sameiro Faria M, Sampaio S, Quintas J, Katus HA, Kaya Z.
    Cardiology. 126(3):173-174, 2013

  • Co-expression network analysis and genetic algorithms for gene prioritization in preeclampsia.
    Tejera E, Bernardes J, Rebelo I.
    BMC Med Genomics, 6:51, 2013

  • Phase transition in tumor growth: I avascular development.
    Izquierdo-Kulich E, Rebelo I, Tejera E, Nieto-Villar JM.
    Physica A, 392:6616–6623, 2013

  • Lipid profile changes by high activity anti-retroviral therapy.
    Duro M, Sarmento-Castro R, Almeida, Medeiros R, Rebelo I.
    Clin Biochem, 46:740–744, 2013

  • The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation.
    Fonseca BM, Correia-da-Silva G, Teixeira NA.
    Apoptosis, 18:1526-1535, 2013

  • The endocannabinoid system in the postimplantation period: a role during Decidualization and Placentation.
    Fonseca BM, Correia-da-Silva G, Almada M, Costa MA, Teixeira NA.
    Int J Endocrinol, 510540-510550, 2013

  • New steroidal 17β-carboxy derivatives present anti-5α-reductase activity and anti-proliferative effects in a human androgen-responsive prostate cancer cell line.
    Amaral C, Varela C, Correia-da-Silva G, Tavares da Silva E, Carvalho RA, Costa SC, Cunha SC, Fernandes JO, Teixeira N, Roleira FM.
    Biochimie, 95:2097-2106, 2013

  • Steroidal aromatase inhibitors inhibit growth of hormone-dependent breast cancer cells by inducing cell cycle arrest and apoptosis.
    Amaral C, Varela C, Borges M, Tavares da Silva E, Roleira FM, Correia-da-Silva G, Teixeira N.
    Apoptosis, 18:1426-1436, 2013

  • Development of a new gas chromatography-mass spectrometry (GC-MS) methodology for the evaluation of 5α-reductase activity.
    Amaral C, Cunha SC, Fernandes JO, Tavares da Silva E, Roleira FM, Teixeira N, Correia-da-Silva G.
    Talanta, 107:154-161, 2013

  • Endogenous cannabinoids revisited: a biochemistry perspective.
    Fonseca BM, Costa MA, Almada M, Correia-da-Silva G, Teixeira NA.
    Prostag Lipid Mediat, 102-103:13-30, 2013

  • Palmitic acid and ergosta-7,22-dien-3-ol contribute to the apoptotic effect and cell cycle arrest of an extract from Marthasterias glacialis L. in neuroblastoma cells.
    Pereira DM, Correia-da-Silva G, Valentão P, Teixeira N, Andrade PB.
    Mar Drugs, 24;12:54-68, 2013

  • Amino acids, fatty acids and sterols profile of some marine organisms from Portuguese waters.
    Pereira DM, Valentão P, Teixeira N, Andrade PB.
    Food Chem, 141:2412-2417, 2013

  • Design, synthesis and biochemical studies of new 7α-allylandrostanes as aromatase inhibitors.
    Varela CL, Amaral C, Correia-da-Silva G, Carvalho RA, Teixeira NA, Costa SC, Roleira FM, Tavares-da-Silva EJ.
    Steroids, 78:662-669, 2013

  • Effects of steroidal aromatase inhibitors on sensitive and resistant breast cancer cells: aromatase inhibition and autophagy.
    Amaral C, Varela C, Azevedo M, da Silva ET, Roleira FM, Chen S, Correia-da-Silva G, Teixeira N.
    J Steroid Biochem Mol Biol, 135:51-59, 2013

  • Hyperbaric oxygen therapy treatment for the recovery of muscle injury induced in rats.
    Maia MCC, Camacho OF, Marques AFP, Coelho PMB.
    Div Hyperbaric Med, 43:222-225, 2013

  • Neuromuscular function, hormonal and redox status and muscle damage of professional soccer players after a high-level competitive match.
    Silva JR, Ascensão A, Marques F, Seabra A, Rebelo A, Magalhães J.
    Eur J Appl Physiol, 9: 2193-2201, 2013

  • A potential mechanism for the pathogenesis of psoriasis vulgaris.
    Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    Int J Dermatol, 52:1429-1432, 2013

  • Bilirubin levels and redox status in a young healthy population.
    Rodrigues C, Rocha E, Nascimento H, Vieira E, Santos R, Santos-Silva A, Costa E, Bronze-da-Rocha E.
    Acta Haematol, 130:57-60, 2013

  • The in vitro and in vivo genotoxicity of isotretinoin assessed with cytokinesis blocked micronucleus assay and comet assay.
    Silva FSG, Oliveira H, Moreiras A, Fernandes JC, Bronze-da-Rocha E, Figueiredo A, Custódio JBA, Rocha-Pereira P, Santos-Silva A.
    Toxicol In Vitro, 27:900-907, 2013

  • Cyto- and genotoxic effects of acitretin alone or combined with psoralen-ultraviolet A and narrowband ultraviolet B therapy in psoriatic patients.
    Silva FSG, Oliveira H, Moreiras A, Fernandes JC, Bronze-da-Rocha E, Figueiredo A, Custódio JBA, Rocha-Pereira P, Santos-Silva A.
    Mutat Res, 753:42-47, 2013

  • A Portuguese case of Fukuyama congenital muscular dystrophy caused by a multi-exonic duplication in the fukutin gene.
    Costa C, Oliveira J, Gonçalves A, Santos R, Bronze-da-Rocha E, Rebelo O, Pais RP, Fineza I.
    Neuromuscul Disord, 23:557-561, 2013

  • Risk factors for mortality in hemodialysis patients: two year follow-up study.
    Faria MS, Ribeiro S, Costa E, Mendonça M, Teixeira L, Rocha-Pereira P, Fernandes J, Nascimento H, Kohlova M, Reis F, Amado L, Bronze-da-Rocha E, Miranda V, Quintanilha A, Belo L, Santos-Silva A.
    Dis Markers, 35:791-798, 2013

  • Circulating cell-free DNA levels in haemodialysis patients and its association with inflammation, iron metabolism and rhEPO doses.
    Kohlova M, Sameiro-Faria M, Rocha-Pereira P, Fernandes J, Reis F, Quintanilha, A Belo, L, Bronze-Rocha E, Costa E, Santos-Silva A.
    Hemodial Int, 17:664-670, 2013

  • Body mass index and resistance to recombinant human erythropoietin therapy in maintenance hemodialysis patients.
    do Sameiro-Faria M, Sandra Ribeiro S, Petronila Rocha-Pereira P, Fernandes J, Reis F, Bronze-da-Rocha E, Miranda V, Quintanilha A, Costa E, Belo L, Santos-Silva A.
    Renal Fail, 35:1392-1398, 2013

  • Factors associated with the length of remission of psoriasis vulgaris.
    Coimbra S, Oliveira H, Figueiredo A, Rocha-Pereira P, Santos-Silva A.
    Clin Drug Investig, 33:855-860, 2013

  • Letter to the Editor: A potential mechanism for the pathogenesis of psoriasis vulgaris.
    Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    Int J Dermatol, 52:1429-1432, 2013

  • The role of adipocytes in the modulation of iron metabolism in obesity.
    Coimbra S, Catarino C, Santos-Silva A.
    Obes Rev, 14:771-779, 2013

  • Principal determinants of the length of remission of psoriasis vulgaris after topical, NB-UVB and PUVA therapy: A follow-up study.
    Coimbra S, Oliveira H, Belo L, Figueiredo A, Rocha-Pereira P, Santos-Silva A.
    Am J Clin Dermatol, 14:49-53, 2013

  • Adipokines, oxidized LDL and C-reactive protein levels in lean, overweight and obese Portuguese patients with type 2 diabetes.
    Neuparth MJ, Proença JB, Santos-Silva A, Coimbra S.
    ISRN Obes, 2013:1-7, 2013

  • Vascular access versus the effect of statins on inflammation and fibrinolysis in renal dialysis patients.
    Faria MS, Ribeiro S, Rocha-Pereira P, Miranda V, Mendonça D, Quintanilha A, Costa E, Belo L, Santos-Silva A.
    J Vasc Access, 14:335–341, 2013

  • Circulating cell-free DNA levels in haemodialysis patients and its association with inflammation, iron metabolism and rhEPO doses.
    Kohlova M, Ribeiro S, do Sameiro-Faria M, Rocha-Pereira P, Fernandes J, Reis F, Miranda V, Quintanilha A, Belo L, Bronze-Rocha E, Costa E, Santos-Silva A.
    Hemodial Int, 17:664–667, 2013

  • Protective activity of hydroxytyrosol metabolites on erythrocyte oxidative-induced hemolysis.
    Paiva-Martins F, Silva A, Almeida V, Carvalheira M, Serra C, Rodríguez-Borges JE, Fernandes JC, Belo L, Santos-Silva A.
    J Agric Food Chem, 61:6636–6642, 2013

  • Effect of whey protein purity and glycerol content upon physical properties of edible films manufactured therefrom.
    Ramos OL, Reinas I, Silva SI, Fernandes JC, Cerqueira MA, Pereira RN, Vicente AA, Poças MF, Pintado ME, Malcata FX.
    Food Hydrocolloids, 30:110-122, 2013

  • Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker.
    Nunes S, Soares E, Fernandes JC, Viana S, Pereira FC, Reis F.
    Cardiovasc Diabetol, 12:44-54, 2013

  • Acitretin affects bioenergetics of liver mitochondria and promotes mitochondrial permeability transition: Potential mechanisms of hepatotoxicity.
    Silva FSG, Ribeiro M, Santos M, Rocha-Pereira P, Santos-Silva A, Custódio JBA.
    Toxicol, 306:93-100, 2013

  • The antiestrogen 4-hydroxytamoxifen protects against isotretinoin-induced permeability transition and bioenergetic dysfunction of liver mitochondria: comparison with tamoxifen.
    Silva FSG, Ribeiro MPC, Santos MS, Rocha-Pereira P, Santos-Silva A, Custódio JBA.
    J Bioenerg Biomemb, 45:383-396, 2013

  • Markers of increased cardiovascular risk in postmenopausal women: focus on oxidized-LDL and HDL subpopulations.
    Mascarenhas-Melo F, Sereno J, Teixeira-Lemos E, Ribeiro S, Rocha-Pereira P, Cotterill E, Teixeira F, Reis F.
    Dis Markers, 35,2:85-96, 2013




2012
  • Apoptosis and autophagy in breast cancer cells following exemestane treatment.
    Amaral C, Borges M, Melo S, da Silva ET, Correia-da-Silva G, Teixeira N.
    PLoS One, 7:e42398–e42408, 2012

  • The rat as an animal model for fetoplacental development: a reappraisal of the post-implantation period.
    Fonseca BM, Correia-da-Silva G, Teixeira NA.
    Reprod Biol, 12:97-118, 2012

  • Characterisation of the endocannabinoid system in rat haemochorial placenta.
    Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Konje JC, Teixeira NA.
    Reprod Toxicol, 34:347-356, 2012

  • New structure-activity relationships of A- and D-ring modified steroidal aromatase inhibitors: design, synthesis, and biochemical evaluation.
    Varela C, Tavares da Silva EJ, Amaral C, Correia da Silva G, Baptista T, Alcaro S, Costa G, Carvalho RA, Teixeira NA, Roleira FM.
    J Med Chem, 55:3992-4002, 2012

  • Plant secondary metabolites in cancer chemotherapy: where are we?
    Pereira DM, Valentao P, Correia-da-Silva G, Teixeira N, Andrade PB.
    Curr Pharm Biotechnol, 13:632-650, 2012

  • Further insights on the carotenoid profile of the echinoderm Marthasterias glacialis.
    Mariutti LRB, Pereira DM, Mercadante AZ, Valentão P, Teixeira N, Andrade PB.
    Mar Drugs, 10:1498-1510, 2012

  • A gas chromatography-mass spectrometry multi-target method for the analysis of three classes of metabolites in marine organisms.
    Pereira DM, Vinholes J, Guedes de Pinho P, Valentão P, Mouga T, Teixeira N, Andrade. PB.
    Talanta, 100:391-400, 2012

  • Molecular and cellular mechanisms of Mycobacterium avium-induced thymic atrophy.
    Borges M, Barreira-Silva P, Flórido M, Jordan MB, Correia-Neves M, Appelberg R.
    J Immunol, 189:3600-3608, 2012

  • Inflammatory disturbances in preeclampsia: Relationship between maternal and umbilical cord blood.
    Catarino C, Santos-Silva A, Belo L, Rocha-Pereira P, Rocha S, Patrício B, Quintanilha A, Rebelo I.
    J Pregnancy, 2012, Art ID 684384, 2012

  • Preeclampsia: a bioinformatics approach through protein-protein interaction networks analysis.
    Tejera E, Bernardes J, Rebelo I.
    BMC Systems Biology, 6:97, 2012

  • Blood pressure and heart rate variability complexity analysis in pregnant women with hypertension.
    Tejera E, Areias MJ, Rodrigues AI, Nieto-Villar JM, Rebelo I.
    Hypertens Pregnancy, 31:91-106, 2012

  • Relationship between heart rate variability indexes and common biochemical markers in normal and hypertensive third trimester pregnancy.
    Tejera E, Areias MJ, Rodrigues AI, Ramõa A, Nieto-Villar JM, Rebelo I.
    Hypertens Pregnancy, 31, 59-69, 2012

  • Bilirubin dependence on UGT1A1 polymorphisms, hemoglobin, fasting time and body mass índex.
    Rodrigues C, Costa E, Vieira E, Carvalho J, Santos R, Rocha-Pereira P, Santos-Silva A, Bronze-da-Rocha E.
    Am J Med Sci, 343:114-118, 2012

  • Impact of UGT1A1 gene variants on total bilirubin levels in Gilbert Syndrome patients and in healthy subjects.
    Rodrigues R, Vieira E, Santos R, Carvalho J, Santos-Silva A, Costa E, Bronze-da-Rocha E.
    Blood Cells Mol Dis, 48:166-172, 2012

  • Evaluation of the reactivity of sera from patients with Systemic Lupus Erythematosus against the human MCP1.
    Bronze-da-Rocha E, Nóvoa A, Teixeira N, Vasconcelos CS, Conceição Cerveira C, Castro-e-Melo J, Carvalho MC.
    J Clin Immunol, 32:721-728, 2012

  • Erythroid disturbances during and after treatment of Portuguese psoriasis vulgaris patients.
    Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    Am J Clin Dermatol, 13:37-47, 2012

  • Cardiac anti-apoptotic and pro-proliferative effect of recombinant human erythropoietin in a moderate stage of chronic renal failure in the rat.
    Teixeira M, Rodrigues-Santos P, Garrido P, Costa E, Parada B, Sereno J, Alves R, Belo L, Teixeira F, Santos-Silva A, Reis F.
    J Pharm Bioallied Sci, 4:76-83, 2012

  • Cardiovascular risk factors in Portuguese obese children and adolescents: Impact of small reductions in body mass index imposed by lifestyle modifications.
    Nascimento H, Costa E, Rocha-Pereira P, Rego C, Ferreira Mansilha H, Quintanilha A, Santos-Silva A, Belo L.
    Open Biochem J, 6:43-50, 2012

  • Oxidized-LDL and lipoprotein (a) levels in chronic kidney disease patients under hemodialysis: influence of adiponectin and of a polymorphism in the apolipoprotein (a) gene.
    Ribeiro S, do Sameiro Faria M, Silva G, Nascimento H, Rocha-Pereira P, Miranda V, Vieira E, Santos R, Mendonça D, Quintanilha A, Costa E, Belo L, Santos-Silva A.
    Hemodial Int, 16:481-490, 2012

  • Adiponectin is an independent predictor of tissue plasminogen activator levels in patients under hemodialysis.
    do Sameiro Faria M, Ribeiro S, Nascimento H, Rocha-Pereira P, Miranda V, Mendonça D, Quintanilha A, Costa E, Belo L, Santos-Silva A.
    Scand J Urol Nephrol, 46:461-465, 2012

  • Main determinants of PON1 activity in hemodialysis patients.
    Ribeiro S, do Sameiro Faria M, Mascarenhas-Melo F, Freitas I, Mendonça MI, Nascimento H, Rocha-Pereira P, Miranda V, Mendonça D, Quintanilha A, Belo L, Costa E, Reis F, Santos-Silva A.
    Am J Nephrol, 36:317-323, 2012

  • Major determinants of BMP-2 serum levels in hemodialysis patients.
    Costa E, Coimbra J, Catarino C, Ribeiro S, Reis F, Nascimento H, Fernandes J, Miranda V, do Sameiro Faria M, Belo L, Santos-Silva A.
    Ren Fail, 34:1355-1358, 2012

  • Inhibition of bladder tumour growth by chitooligosaccharides.
    Fernandes JC, Garrido P, Sereno J, Parada B, Pintado ME, Reis F, Santos-Silva A.
    Mar Drugs, 10:2661-2675, 2012

  • Evaluation of chitooligosaccharides effect upon probiotic bacteria.
    Fernandes JC, Franco I, Eaton P, Ramos OS, Gomes AM, Santos-Silva A, Malcata FX, Pintado ME.
    Int J Biol Macromol, 50:148-152, 2012

  • Features and performance of edible films, obtained from whey protein isolate formulated with antimicrobial compounds.
    Ramos OL, Silva SI, Soares JC, Fernandes JC, Poças MF, Pintado ME, Malcata FX.
    Food Res Int, 45:351-361, 2012

  • Edible films and coatings from whey proteins: a review on formulation, and on mechanical and bioactive properties.
    Ramos OL, Fernandes JC, Silva SI, Pintado ME, Malcata FX.
    Crit Rev Food Sci Nutr, 52:533-552, 2012

  • Study of Antimicrobial Activity and Atomic Force Microscopy Imaging of the Action Mechanism of Cashew Tree Gum.
    Campos DA, Ribeiro AC, Costa EM, Fernandes JC, Tavaria FK, Araruna F, Eiras C, Eaton P, Leite JR, Pintado ME
    Carbohydr Polym, 90:270-274, 2012

  • Effect of composition of commercial whey protein preparations upon gelation at various pH values.
    Ramos OL, Pereira JO, Silva SI, Amorim MM, Fernandes JC, Lopes-da-Silva JA, Pintado ME, Malcata FX.
    Food Res Int, 48:681-689, 2012

  • Evaluation of antimicrobial edible whey protein isolate coatings to improve the storability of Saloio cheese.
    Ramos OL, Pereira JO, Silva SI, Fernandes JC, Franco MI, Lopes-da-Silva JA, Pintado ME, Malcata FX.
    J Dairy Sci, 95:6282-6292, 2012

  • Antimicrobial activities of edible coatings prepared from whey protein isolate, and formulated with various antimicrobial agents: in vitro studies.
    Ramos OL, Santos AC, Leão MV, Silva SI, Fernandes JC, Franco MI, Pintado ME, Malcata FX.
    Int Dairy J, 25:132-141, 2012

  • Voltammetric immunosensor for the diagnosis of celiac disease based on the quantification of anti-gliadin antibodies.
    Neves M, González-García MB, Santos-Silva A, Costa-Garcia A.
    Sensors Actuators B-Chem, 163:253-259, 2012




2011
  • Artificial neural network for normal, hypertensive, and preeclamptic pregnancy classification using maternal heart rate variability indexes.
    Tejera E, Jose Areias M, Rodrigues A, Ramõa A, Manuel Nieto-Villar J, Rebelo I.
    J Maternal-Fetal Neonatal Med, 24:1147-1151, 2011

  • Network centrality and multiscale transition asymmetry in the heart rate variability analysis of normal and preeclamptic pregnancies.
    Tejera E, Rodrigues AI, Areias MJ, Rebelo I, Nieto-Villar JM.
    Commun Nonlinear Sci Numer Simulat, 16:1589-1596, 2011

  • Modulation of the novel cannabinoid receptor - GPR55 - during rat fetoplacental development.
    Fonseca BM, Teixeira NA, Almada M, Taylor AH, Konje JC, Correia-da-Silva G.
    Placenta, 32:462-469, 2011

  • Fatty acids in marine organisms: In the pursuit of bioactive agentes.
    Pereira DM, Vinholes J, Correia-da-Silva G, Valentão P, Teixeira N, Andrade PB.
    Curr Pharm Anal, 7:108-119, 2011

  • The death-promoting molecule tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium.
    Borges M, Rosa GT, Appelberg R.
    Clin Exp Immunol, 164:407-416, 2011

  • Flavonoids with an oligopolysulfated moiety: A new class of anticoagulant agents.
    Correia-Da-Silva M, Sousa E, Duarte B, Marques F, Carvalho F, Cunha-Ribeiro LM, Pinto MMM.
    J Med Chem, 54: 95-106, 2011

  • Hyperbaric oxygen effects on sports injuries.
    Barata P, Cervaens M, Resende R, Camacho O, Marques F
    Therap Adv Musc Dis, 3: 1-11, 2011

  • Polysulfated xanthones: multipathway development of a new generation of dual anticoagulant/antiplatelet agents.
    Correia-Da-Silva M, Sousa E, Duarte B, Marques F, Carvalho F, Cunha-Ribeiro LM, Pinto MMM.
    J Med Chem, 54:5373-5384, 2011

  • Dual anticoagulant/antiplatelet persulfated small molecules.
    Correia-Da-Silva M, Sousa E, Duarte B, Marques F, Carvalho F, Cunha-Ribeiro LM, Pinto MMM.
    Eur J Med Chem, 46: 2347-2358, 2011

  • Influence of dietary supplementation with dextrin or oligofructose on the hepatic redox balance in rats.
    Kozmus CEP, Moura E, Serrão MP, Real H, Guimarães JT, Guedes-de-Pinho P, Duarte BP, Marques F, Martins MJ, Vieira-Coelho MA.
    Mol Nut Food Res, 55:1735-1739, 2011

  • Acute Exercise Protects Against Calcium-induced Cardiac Mitochondrial Permeability Transition Pore in Doxorubicin Treated Rats.
    Ascensão A, Lumini-Oliveira J, Machado N, Ferreira R, Gonçalves IO, Moreira AC, Marques F, Sardão V, Oliveira PJ, Magalhaes J
    Clin Sci, 120:37-49, 2011

  • Interactions of MCP1 with components of the replication machinery in mammalian cells.
    Bronze-da-Rocha E, Lin C-M, Shimura T, Aladjem MI.
    Int J Biol Sci, 7:193-208, 2011

  • Novel ancestral dysferlin splicing mutation which migrated from the Iberian peninsula to South America.
    Vernengo L, Oliveira J, Krahn M, Vieira E, Santos R, Carrasco L, Negrão L, Panuncio A, Leturcq F, Labelle V, Bronze-da-Rocha E, Mesa R, Pizzarossa C, Lévy N, Rodriguez MM.
    Neuromuscul Disord, 21:328-337, 2011

  • Cytotoxicity and genotoxicity of chitooligosaccharides upon lymphocytes.
    Fernandes JC, Borges M, Nascimento H, Bronze-da-Rocha E, Ramos OS, Pintado ME, Malcata FX, Santos-Silva A.
    Int J Biol Macromol, 49:433-438, 2011

  • Complementary markers for the clinical severity classification of Hereditary Spherocytosis in unsplenectomized patients.
    Rocha S, Costa E, Rocha-Pereira P, Ferreira F, Cleto E, Barbot J, Quintanilha A, Belo L, Santos-Silva A.
    Blood Cells Mol Dis, 46:166-170, 2011

  • Elastase release during the hemodialysis procedure seems to induce changes in red blood cell membrane proteins.
    Pereira R, Rocha S, Borges A, Nascimento H, Reis F, Miranda V, Sameiro Faria MD, Quintanilha A, Belo L, Costa E, Santos-Silva A.
    Hemodialysis Int, 15:429-431, 2011

  • Erythropoiesis versus inflammation in Hereditary Spherocytosis clinical outcome.
    Rocha S, Rocha-Pereira P, Ferreira F, Cleto E, Barbot J, Quintanilha A, Belo L, Santos-Silva A.
    Clin Biochem, 44:1137-1143, 2011

  • Health-related quality of life in Portuguese psoriatic patients: relation with PASI and different types of classical psoriatic treatment.
    Coimbra S, Oliveira H, Reis F, Belo L, Carvalho A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    Am J Dermatol, 38:816-819, 2011

  • Apoptosis of peripheral CD4+ T-lymphocytes in end-stage renal disease patients under hemodialysis and rhEPO therapies.
    Borges A, Borges M, Fernandes J, Nascimento H, Sameiro-Faria M, Miranda V, Reis F, Belo L, Costa E, Santos-Silva A.
    Ren Fail, 33:138-143, 2011

  • Animal Model of Implant Capsule Contracture: effects of chitosan.
    Marques M, Brown SA, Richardson J, Morales-Helguera A, Fernandes JC, Freitas R, Amarante J.
    Aesthetic Surg J, 31: 540-550, 2011

  • Morphine Patient Controlled Analgesia for Postoperative Analgesia in Patients Who Have Transplanted Cadaver Donor Kidneys.
    Madeira I, Frada R, Marvão J, Cruz F, Casal M, Costa E.
    Transplant Proc 43, 1:125-130, 2011

  • Comparison of Bio-Plex measurements with standard techniques.
    Ribeiro S, Nascimento H, Borges A, do Sameiro Faria M, Rocha-Pereira P, Costa E, Belo L, Santos-Silva A.
    Clin Chem Lab Med, 50:399-402, 2011




2010
  • Toxicological effects of recombinant human erythropoietin doping - chonic versus acute aerobic exercice.
    Piloto N, Teixeira HM, Teixeira de LE, Parada B, Garrido P, Sereno J, Ferreira I, Costa E, Belo L, Santos-Silva A, Rocha-Pereira P, Pego J, Marques G, Lourenço M, Tavares CA, Alves R, Teixeira F, Reis F.
    Acta Medicinae Legalis et Socialis, pp 275-282.
    Imprensa da Universidade de Coimbra - International Academy of Legal Medicine, 2010.

  • Erythropoietin doping as cause of sudden death in athletes - an experimental study.
    Piloto N, Teixeira HM, Teixeira de LE, Parada B, Garrido P, Sereno J, Pinto AF, Costa E, Belo L, Santos-Silva A, Pinto R, Couceiro P, Neto P, Xavier F, Carvalho L, Teixeira F, Reis F.
    Acta Medicinae Legalis et Socialis, pp 267-273.
    Imprensa da Universidade de Coimbra - International Academy of Legal Medicine, 2010.

  • Unexpected heart rate variability complexity in the aging process of arrhythmic subjects.
    Tejera E, Nieto-Villar JM, Rebelo I.
    Commun Nonlinear Sci Numer Simulat, 15:1858-1863, 2010

  • Lipid levels including oxidized LDL in women with history of preeclampsia.
    Portelinha A, Belo L, Cerdeira AS, Braga J, Tejera E, Pinto F, Pinto A, Areias MJ, Patrício B, Rebelo I.
    Hypertens Pregnancy, 29:93-100, 2010

  • The endocannabinoid 2-arachidonoylglycerol (2-AG) and metabolizing enzymes during rat fetoplacental development: a role in uterine remodelling.
    Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Bell SC, Konje JC, Teixeira NA.
    Int J Biochem Cell Biol, 42:1884-1892, 2010

  • N-acylethanolamine levels and expression of their metabolizing enzymes during pregnancy.
    Fonseca BM, Correia-da-Silva G, Taylor AH, Lam PM, Marczylo TH, Konje JC, Bell SC, Teixeira NA.
    Endocrinol, 151:3965-3974. 2010

  • Impact of Loughborough Intermittent Shuttle Test versus soccer match on physiological, biochemical and neuromuscular parameters.
    Magalhães J, Rebelo A, Oliveira E, Silva JR, Marques F, Ascensão A.
    Eur J Appl Physiol, 108: 39-48, 2010

  • Long-term hyperglycaemia decreases gastrocnemius mitochondrial susceptibily to permeability transition.
    Lumini-Oliveira J, Ascensão A, Pereira CV, Magalhães S, Marques F, Oliveira PJ, Magalhães J.
    Eur J Clin Invest, 40:319-329, 2010.

  • Multicomponent exercise program improves blood lipid profile and antioxidant capacity in older women.
    Carvalho J, Marques E, Ascensão A, Magalhães J, Marques F, Mota J
    Arch Gerontol Geriatrics, 51:1-5, 2010

  • Effects of chronic red wine consumption on the expression of vascular endothelial growth factor, angiopoietin 1, angiopoietin 2, and its receptors in rat erectile tissue.
    Neves DR, Tomada IM, Assunção MM, Marques FA, Almeida HM, Andrade JP
    J Food Sci, 75:H79-H86, 2010

  • Private dysferlin exon skipping mutation (c.5492G>A) with a founder effect reveals further alternative splicing involving exons 49-51.
    Santos R, Oliveira J, Vieira E, Coelho T, Carneiro AL, Evangelista T, Dias C, Fortuna A, Geraldo A, Negrão L, Guimarães A, Bronze-da-Rocha E.
    J Hum Genet, 55:546-549, 2010

  • Powerful protective role of 3,4-dihydroxyphenylethanol-elenolic acid dialdehyde against erythrocyte oxidative-induced hemolysis.
    Paiva-Martins F, Fernandes J, Santos V, Silva L, Borges F, Rocha S, Belo L, Santos-Silva A.
    J Agricult Food Chem, 58:135-140, 2010

  • Hereditary Spherocytosis and the (TA)nTAA polymorphism of UGT1A1 gene promoter region – A comparison of the bilirubin plasmatic levels in the different clinical forms.
    Rocha S, Costa E, Ferreira F, Cleto E, Barbot J, Rocha-Pereira P, Quintanilha A, Belo L, Santos-Silva A.
    Blood Cells Mol Dis, 44:117-119, 2010

  • In vitro studies with 'acatalasemic-like' erythrocytes and hydrogen peroxide: attention to the formation of lysis resistant erythrocytes.
    Nascimento H, Belo L, Fernandes J, Rocha S, Quintanilha A, Santos-Silva A.
    Int J Lab Hematol, 32:127-131, 2010

  • Erythrocyte membrane protein destabilization versus clinical outcome in 160 Portuguese Hereditary Spherocytosis patients.
    Rocha S, Costa E, Rocha-Pereira P, Ferreira F, Cleto E, Barbot J, Quintanilha A, Belo L, Santos-Silva A.
    Br J Haematol, 149:785-794, 2010

  • C-reactive protein and leucocyte activation in psoriasis vulgaris according to severity and therapy.
    Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    J Eur Acad Dermatol Venereol, 24:789-796, 2010

  • Circulating adipokine levels in Portuguese patients with psoriasis vulgaris according to body mass index, severity and therapy.
    Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    J Eur Acad Dermatol Venereol, 24:1386-1394, 2010

  • Psoriasis therapy and cardiovascular risk factors: a 12-week follow-up study.
    Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    Am J Clin Dermatol, 11:423-432, 2010

  • Interleukin (IL)-22, IL-17, IL-23, vascular endothelial growth factor and tumour necrosis factor-α levels in patients with psoriasis before, during and after psoralen-ultraviolet A and narrowband ultraviolet B therapy.
    Coimbra S, Oliveira H, Reis F, Belo L, Rocha S, Quintanilha A, Figueiredo A, Teixeira F, Castro E, Rocha-Pereira P, Santos-Silva A.
    Br J Dermatol, 163:1282-1290, 2010

  • Leukocyte count versus C-reactive protein levels in obese Portuguese patients aged 6-12 years old.
    Nascimento H, Rocha S, Rego C, Mansilha H F, Quintanilha A, Santos-Silva A, Belo L.
    Open Biochem J, 4:72-76, 2010

  • Effect of recombinant human erythropoietin in a rat model of moderate chronic renal failure – focus on inflammation, oxidative stress and function/renoprotection.
    Garrido P, Reis F, Costa E, Almeida A, Parada B, Teixeira de Lemos E, Santos P, Alves R, Sereno J, Pinto R, Tavares CA, Figueiredo A, Rocha-Pereira P, Belo L, Santos-Silva A, Teixeira F.
    Open Drug Discov J, 2:25-32, 2010

  • Plant aqueous extracts: antioxidant capacity via haemolysis and bacteriophage P22 protection.
    Gião MS, Leitão I, Pereira A, Borges AB, Guedes CJ, Fernandes JC, Belo L, Santos-Silva A, Hogg TA, Pintado ME, Malcata FXL.
    Food Control, 21:633-638, 2010

  • Lipid levels including oxidized LDL in women with history of preeclampsia.
    Portelinha A, Belo L, Cerdeira AS, Braga J, Tejera E, Pinto F, Pinto A, Areias MJ, Patrício B, Rebelo I.
    Hypertens Pregnancy, 29:93-100, 2010

  • Neutrophil and monocyte activation in chronic kidney disease patients under hemodialysis and its relationship with resistance to recombinant human erythropoietin and to the hemodialysis procedure.
    Pereira R, Costa E, Gonçalves M, Miranda V, Sameiro Faria MD, Quintanilha A, Belo L, Lima M, Santos-Silva A.
    Hemodial Int, 14:295-301, 2010

  • Recombinant human erythropoietin treatment protects the cardio-renal axis in a model of moderate chronic renal failure.
    Teixeira AM, Garrido P, Santos P, Alves R, Parada B, Costa E, Almeida A, Teixeira-Lemos E, Sereno J, Pinto R, Belo L, Santos-Silva A, Teixeira F, Reis F.
    Ren Fail, 32:1073-1080, 2010

  • Antioxidant activity of chitooligosaccharides upon two biological systems: erythrocytes and bacteriophages.
    Fernandes JC, Eaton P, Nascimento H, Gião MS, Ramos OS, Belo L, Santos-Silva A, Pintado ME, Malcata FX.
    Carbohydr Polym, 79:1101-1106, 2010

  • Anti-inflammatory activity of chitooligosaccharides in vivo.
    Fernandes JC, Spindola H, de Sousa V, Santos-Silva A, Pintado ME, Carvalho JE, Malcata FX.
    Mar Drugs, 8: 1763-1768, 2010

  • Potential therapeutic use of recombinant human erythropoietin (Guest Editor).
    Costa E.
    Open Drug Discov J, 2:1-35, 2010

  • Celiac disease diagnosis and glúten-free food analytical control.
    Da Silva Neves MM, González-Garcia MB, Nouws HP, Delerue-matos C, Santos-Silva A, Costa-García A.
    Analyt Bioanalyt Chem, 397: 1743-1753, 2010






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