Presence of Antibodies against Genogroup VI Norovirus in Humans

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

Joao Rodrigo Mesquita (Autor) Outra; Veronica P Costantini (Autor) Outra; Jennifer L Cannon (Autor) Outra; Seh ching Lin (Autor) Outra; Maria Sao J Jose Nascimento (Autor) FFUP; Jan Vinje (Autor) Outra

Revista

Título: Virology Journal

Vol. 10

Página Final: 176

ISSN: 1743-422X

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 27 Citações

Scopus - 20 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Ciências biológicas

Outras Informações

ID Authenticus: P-005-02S

DOI: 10.1186/1743-422x-10-176

Abstract (EN): Background: Noroviruses are important enteric pathogens in humans and animals. Recently, we reported a novel canine norovirus (CaNoV) in dogs with diarrhea belonging to a new genogroup (GVI). No data are available on exposure of humans to this virus. Methods: Sera from 373 small animal veterinarians and 120 age-matched population controls were tested for IgG antibodies to CaNoV by a recombinant virus like particle based enzyme-linked immunosorbent assay. Results: Antibodies to CaNoV were found in 22.3% of the veterinarians and 5.8% of the control group (p<0.001). Mean corrected OD450 values for CaNoV antibodies were significantly higher in small animal veterinarians compared to the control group. Conclusions: These findings suggest that CaNoV may infect humans and small animal veterinarians are at an increased risk for exposure to this virus. Additional studies are needed to assess if this virus is able to cause disease in humans.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5