A Simple Model for the Identification of Drug Effects

• Tipo: Artigo em Livro de Atas de Conferência Internacional
• Data: 2009

Autores

Hugo Alonso (Autor) FEUP; Teresa Mendonca (Autor) FCUP; Joao M Lemos (Autor) Outra; Torbjorm Wigren (Autor) Outra

Ata de Conferência Internacional

Título: WISP 2009: 6TH IEEE INTERNATIONAL SYMPOSIUM ON INTELLIGENT SIGNAL PROCESSING, PROCEEDINGS

Páginas: 269-273

6th IEEE International Symposium on Intelligent Signal Processing

Budapest, HUNGARY, AUG 26-28, 2009

Indexação

ISI Web of Knowledge - 6 Citações

Scopus - 7 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia electrotécnica, electrónica e informática

Outras Informações

ID Authenticus: P-003-SDE

DOI: 10.1109/wisp.2009.5286552

Abstract (EN): This paper presents a new model for the identification of drug effects. The main advantage of this model over standard models is its simplicity. In fact, the proposed model establishes an affine relation between the drug infusion rate and the corresponding effect on the patient where there are few parameters to estimate, while standard models usually assume a nonlinear relation with many parameters to estimate. Furthermore, it is shown that the new model has a good ability to describe real data. Here, the case study focuses on the muscle relaxant atracurium and its influence on the neuromuscular blockade, but other drugs such as the hypnotic propofol and the analgesic remifentanil and their influence on the depth of anaesthesia may also be considered.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5