Poorly differentiated carcinomas of the thyroid gland - A review of the clinicopathologic features of a series of 28 cases of a heterogeneous, clinically aggressive group of thyroid tumors

• Tipo: Artigo em Revista Científica Internacional
• Data: 2002

Autores

Sobrinho Simoes, M (Autor) FMUP; Sambade, C (Autor) Outra; Fonseca, E (Autor) Outra; Soares, P (Autor) FMUP

Revista

Título: International Journal of Surgical Pathology

Vol. 10

Páginas: 123-131

ISSN: 1066-8969

Editora: SAGE

Indexação

ISI Web of Knowledge - 50 Citações

Scopus - 62 Citações

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina básica

Outras Informações

ID Authenticus: P-000-PTY

DOI: 10.1177/106689690201000205

Abstract (EN): We evaluated the clinicopathologic, immunohistochemical, lectin histochemical, ultrastructural and morphometric characteristics of a series of 28 poorly differentiated carcinomas of the thyroid (PDCT). The 28 tumors were classified according to their predominant growth pattern as insular (n=12), trabecular (n=10) and solid subtypes (n=6). The overall mortality rate was 46%. No significant differences were found among the 3 subtypes. Data obtained by lectin histochemistry, electron microscopy, and morphometry point to a closer relationship of PDCT to follicular than to papillary carcinoma. Our results do not support the subdivision of PDCT into subtypes.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9