Liver transplantation for the treatment of type I familial amyloidotic polyneuropathy [Trasplante hepático para el tratamiento de la polineuropatía amiloidótica familiar tipo I.]

• Tipo: Artigo em Revista Científica Internacional
• Data: 1993

Autores

Lopez Andreu, FR (Autor) Outra; Munar Ques, M (Autor) Outra; Parrilla, P (Autor) Outra; Escribano Soriano, JB (Autor) Outra; Costa, PP (Autor) Outra; Costa, PM (Autor) ICBAS; Almeida, MR (Autor) ICBAS; Pons, JA (Autor) Outra; Robles, R (Autor) Outra; Sanchez Bueno, F (Autor) Outra

Revista

Título: Medicina Clinica

Vol. 101

Páginas: 581-583

ISSN: 0025-7753

Editora: Elsevier

Indexação

ISI Web of Knowledge

Scopus - 8 Citações

Outras Informações

ID Authenticus: P-007-AXV

Abstract (EN): The first liver transplantation carried out in Spain for the treatment of type I familial amyloidotic polyneuropathy (FAP I) is presented. The reason for the operation was based on the liver being responsible for the synthesis of abnormal transtirretin (TTR) constituting the peculiar amyloid of the disease. Following transplantation a rapid and noticeable decrease in abnormal TTR was observed and the evolution of the clinical picture after 18 months of surgery is favorable with progressive improvement of the neurologic symptoms and normal function of the graft. These encouraging results coincide with those of the Swedish group of Umea, the pioneer of this procedure.

Idioma: Espanhol

Tipo (Avaliação Docente): Científica

Nº de páginas: 3