Identification of a 24 kDa intrinsic membrane protein from mammalian peroxisomes

• Tipo: Artigo em Revista Científica Internacional
• Data: 1999

Autores

reguenga, c (Autor) Outra; oliveira, mem (Autor) Outra; gouveia, amm (Autor) Outra; eckerskorn, c (Autor) Outra; sa-miranda, c (Autor) Outra; azevedo, je (Autor) ICBAS

Revista

Título: Biochimica et Biophysica Acta - Gene Structure and Expression

Vol. 1445

Páginas: 337-341

ISSN: 0167-4781

Editora: Elsevier B.V.

Indexação

ISI Web of Knowledge - 21 Citações

Scopus - 22 Citações

Outras Informações

ID Authenticus: P-001-42S

DOI: 10.1016/s0167-4781(99)00061-5

Abstract (EN): A 24 kDa protein from rat liver peroxisomal membrane was isolated and subjected to Edman degradation. Using the N-terminal sequence of this polypeptide we have identified several rat and human expressed sequence tags in the GenBank Database. The complete sequence of a human cDNA clone was determined, The open reading frame encodes an extremely basic protein 212 amino acid residues long. A high similarity between this mammalian protein and hypothetical proteins from Caenorhabditis elegans and Neurospora crassa was found. Hydropathy analysis reveals the existence of two putative membrane-spanning domains in conserved regions of the three homologous proteins.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5