Protein translocation across the peroxisomal membrane

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2004

Autores

azevedo, je (Autor) ICBAS; costa-rodrigues, j (Autor) Outra; guimaraes, cp (Autor) Outra; oliveira, me (Autor) Outra; sa-miranda, c (Autor) Outra

Revista

Título: Cell Biochemistry and Biophysics

Vol. 41

Páginas: 451-468

ISSN: 1085-9195

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 22 Citações

Scopus - 23 Citações

Outras Informações

ID Authenticus: P-000-CE7

DOI: 10.1385/cbb:41:3:451

Abstract (EN): Peroxisomal matrix proteins are synthesized on free cytosolic ribosomes and posttranslationally imported into the organelle. Translocation of these newly synthesized proteins across the peroxisomal membrane requires the concerted action of many different proteins, the majority of which were already identified. However, not much is known regarding the mechanism of protein translocation across this membrane system. Here, we discuss recent mechanistic and structural data. These results point to a model in which proteins en route to the peroxisomal matrix are translocated across the organelle membrane by their own receptor in a process that occurs through a large membrane protein assembly.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 18