Synthesis, crystal structure and spectral properties of 6-bromo-N-(cyclohex-1-en-1-ylmethyl)-4-oxo-4H-chromene-2-carboxamide

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

cagide, fernando (Autor) FCUP; borges, fernanda (Autor) FCUP; gomes, ligia rebelo (Autor) Outra; low, john nicolson (Autor) Outra

Revista

Título: Journal of Molecular Structure

Vol. 1049

Páginas: 125-131

ISSN: 0022-2860

Editora: Elsevier

Indexação

ISI Web of Knowledge - 1 Citação

Scopus - 1 Citação

Outras Informações

ID Authenticus: P-006-6MG

DOI: 10.1016/j.molstruc.2013.06.028

Abstract (EN): In this work the synthesis of a new chromone (6-bromo-N-(cyclohex-1-en-1-ylmethyl)-4-oxo-4H-chromene-2-carboxamide) by a strategy performed in three steps is reported. The compound was characterized by NMR (H-1 and C-13) and EIMS and the structure was confirmed by single-crystal X-ray diffraction. The analysis of the X-ray determined that the molecule is built up from two rings, a chromone ring and a cyclohexene ring united by an amide spacer. This new chromone will be valuable for obtaining evidence about the importance of the exocyclic double bound on monoaminoxidase-B (MAO-B) inhibitory activity. (c) 2013 Published by Elsevier B.V.

Idioma: Inglês

Tipo (Avaliação Docente): Científica