Oxidative behaviour of apomorphine and its metabolites

• Tipo: Artigo em Revista Científica Internacional
• Data: 2002

Autores

Garrido, JMPJ (Autor) Outra; Delerue Matos, C (Autor) Outra; Borges, MFM (Autor) FFUP; Macedo, TRA (Autor) Outra; Oliveira Brett, AM (Autor) Outra

Revista

Título: Bioelectrochemistry

Vol. 55

ISSN: 1567-5394

Editora: Elsevier

Indexação

ISI Web of Knowledge - 11 Citações

Scopus - 14 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

Outras Informações

ID Authenticus: P-000-QWQ

Abstract (EN): The metabolism of apomorphine is quite complex due to interactions with proteins and other tissue components that affect its pharmacokinetic profile. The electrochemical oxidation mechanism of apomorphine and of some synthesised apomorphine derivatives was studied. It was found to be related to the reaction of o-diphenol and tertiary amine groups and strongly dependent on pH. (C) 2002 Elsevier Science B.V. All rights reserved.

Idioma: Inglês

Tipo (Avaliação Docente): Científica