Complicated intra-abdominal infections in Europe: a comprehensive review of the CIAO study.

• Tipo: Artigo em Revista Científica Internacional
• Data: 2012

Autores

de Melo RB (Autor) FMUP

Revista

Título: World Journal of Emergency Surgery

ISSN: 1749-7922

Editora: Springer Nature

Indexação

Pubmed / Medline

Classificação Científica

FOS: Ciências médicas e da saúde > Medicina clínica

Outras Informações

Abstract (EN): The CIAO Study ("Complicated Intra-Abdominal infection Observational" Study) is a multicenter investigation performed in 68 medical institutions throughout Europe over the course of a 6-month observational period (January-June 2012).Patients with either community-acquired or healthcare-associated complicated intra-abdominal infections (IAIs) were included in the study.2,152 patients with a mean age of 53.8 years (range: 4-98 years) were enrolled in the study. 46.3% of the patients were women and 53.7% were men. Intraperitoneal specimens were collected from 62.2% of the enrolled patients, and from these samples, a variety of microorganisms were collectively identified.The overall mortality rate was 7.5% (163/2.152).According to multivariate analysis of the compiled data, several criteria were found to be independent variables predictive of patient mortality, including patient age, the presence of an intestinal non-appendicular source of infection (colonic non-diverticular perforation, complicated diverticulitis, small bowel perforation), a delayed initial intervention (a delay exceeding 24 hours), sepsis and septic shock in the immediate post-operative period, and ICU admission.Given the sweeping geographical distribution of the participating medical centers, the CIAO Study gives an accurate description of the epidemiological, clinical, microbiological, and treatment profiles of complicated intra-abdominal infections (IAIs) throughout Europe.

Idioma: Inglês

Tipo (Avaliação Docente): Científica