Maternal Early-onset Preeclampsia Places Preterm Infants at Risk of Thrombocytopenia Requiring Platelet Transfusions

• Tipo: Artigo em Revista Científica Internacional
• Data: 2025

Autores

Pereira, J (Autor) Outra; Rabiço Costa, D (Autor) Outra; Marques, M (Autor) Outra; Moita, R (Autor) Outra; Ferreras, C (Autor) Outra; Flôr De Lima, F (Autor) Outra; Inês Azevedo (Autor) FMUP; Rocha, G (Autor) Outra

Revista

Título: Journal of Pediatric Hematology/Oncology

Vol. 47

Páginas: 177-184

ISSN: 1077-4114

Editora: Wolters Kluwer Health

Indexação

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-018-K6Y

DOI: 10.1097/mph.0000000000003022

Abstract (EN): Objectives: Evaluate the hematological parameters and indices in the blood count collected on the first day of life (D1) in very premature infants born to mothers with early-onset preeclampsia (PE) and their correlation with increased neonatal morbimortality. Background: Changes in hematologic parameters in the blood counts collected after birth associated with PE have been demonstrated by recent studies, although inconsistently. Materials and Methods: Retrospective study between 2008 and 2023, at a level III neonatal intensive care unit, including preterm infants with a gestational age below 30 weeks. A blood count was collected on D1 and a comparison of hematological parameters and indices was made between infants exposed or not to PE. Results: We included 206 newborns (PE = 39; no PE = 167). The multivariate analyses showed no significant hematological changes. PE-exposed infants required significantly more platelet transfusions (PE: n = 20 [51.8%]; no PE: n = 34 [20.36%]; P < 0.0001). Conclusion: PE-exposed preterms required more platelet transfusions, which increases the risk of associated complications. Copyright © 2025 Wolters Kluwer Health, Inc.

Idioma: Inglês

Tipo (Avaliação Docente): Científica