Current strategies for osteochondral regeneration: from stem cells to pre-clinical approaches

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2011

Autores

Rodrigues, MT (Autor) Outra; Gomes, ME (Autor) Outra; Rui Reis (Autor) Outra

Revista

Título: Current Opinion in Biotechnology

Vol. 22

Páginas: 726-733

ISSN: 0958-1669

Editora: Elsevier

Indexação

ISI Web of Knowledge - 42 Citações

Scopus - 47 Citações

Outras Informações

ID Authenticus: P-002-KX3

DOI: 10.1016/j.copbio.2011.04.006

Abstract (EN): Damaged cartilage tissue has no functional replacement alternatives and current therapies for bone injury treatment are far from being the ideal solutions emphasizing an urgent need for alternative therapeutic approaches for osteochondral (OC) regeneration.The tissue engineering field provides new possibilities for therapeutics and regeneration in rheumatology and orthopaedics, holding the potential for improving the quality of life of millions of patients by exploring new strategies towards the development of biological substitutes to maintain, repair and improve OC tissue function. Numerous studies have focused on the development of distinct tissue engineering strategies that could result in promising solutions for this delicate interface. In order to outperform currently used methods, novel tissue engineering approaches propose, for example, the design of multi-layered scaffolds, the use of stem cells, bioreactors or the combination of clinical techniques.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 8