<p>Toxicity of microplastics and copper, alone or combined, in blackspot seabream (Pagellus bogaraveo) larvae<br></p>

• Tipo: Artigo em Revista Científica Internacional
• Data: 2022

Autores

Santos, D (Autor) Outra; Perez, M (Autor) Outra; Perez, E (Autor) Outra; Cabecinha, E (Autor) Outra; Luzio, A (Autor) Outra; Felix, L (Autor) Outra; Monteiro, SM (Autor) Outra; Bellas, J (Autor) Outra

Revista

Título: Environmental Toxicology and Pharmacology

Vol. 91

ISSN: 1382-6689

Editora: Elsevier

Indexação

ISI Web of Knowledge - 1 Citação

Outras Informações

ID Authenticus: P-00W-M0S

DOI: 10.1016/j.etap.2022.103835

Abstract (EN): Plastics pose serious risks for fish productivity and a potential constraint for food security. Newly hatched blackspot seabream larvae were exposed to microplastics (MPs), copper (Cu, 10-810 mu g/L) and their mixtures (Cu+MPs), during 3 and 9 days. Biochemical biomarkers and the expression of antioxidant and neurotoxicity-related genes were evaluated.& nbsp;In the 3-day exposure, catalase and glutathione-S-transferase activities decreased in MPs, Cu and Cu+MPs groups, followed by an increase of lipid peroxidation in the Cu270 and Cu270 + MPs exposed larvae. In the 9-day exposure, ROS levels increased in MPs and Cu30 groups, but no significant oxidative damage was observed, suggesting that the antioxidant system overcome the induced oxidative stress. However, the acetylcholinesterase transcript was downregulated in MPs, Cu and Cu10+MPs groups, indicating that MPs effects in cholinergic neurotransmission may arise after longer exposures. Overall, MPs and Cu can reduce survival, induce oxidative stress, lipid peroxidation, neurotoxicity, and impact negatively fish larvae fitness.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 14