Biopesticide spinosad: Unraveling ecotoxicological effects on zebrafish, Danio rerio

• Tipo: Artigo em Revista Científica Internacional
• Data: 2024

Autores

Amaral, I (Autor) Outra; Antunes, SC (Autor) FCUP; Rebelo, D (Autor) Outra; Carvalho, AP (Autor) FCUP; Rodrigues, S (Autor) Outra

Revista

Título: Environmental Toxicology and Pharmacology

Vol. 108

ISSN: 1382-6689

Editora: Elsevier

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-010-D2W

DOI: 10.1016/j.etap.2024.104458

Abstract (EN): Biopesticides are natural compounds considered more safe and sustainable for the environment. Spinosad (SPI) is a bioinsecticide used in marketed worldwide, to eradicate a variety of pests. This study aimed to assess the impacts of the SPI on the non-target organism zebrafish (Danio rerio). Several concentrations of SPI were tested to evaluate the acute (0.07-1.0 mg/L) and chronic (0.006-0.100 mg/L) ecotoxicological effects. To evaluate subindividual effects, antioxidant defense, lipid peroxidation, energy sources, and cholinergic biomarkers were quantified. In both exposures, SPI induced significant effects on antioxidant defense indicating oxidative stress, disrupting energy pathways, and exhibiting neurotoxic effects, under environmentally relevant conditions. Integrated Biomarker Response (IBRv2) showed that with increasing SPI concentrations, an increase in impacts on organisms was recorded. This study demonstrates the vulnerability of a non-target organism to SPI, a bioinsecticide considered environmentally safe. Further research is essential to fully understand the implications of spinosad to aquatic biota.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 10