Phenolics and antimicrobial activity of traditional stoned table olives ‘alcaparra’

• Tipo: Artigo em Revista Científica Internacional
• Data: 2006

Autores

Anabela Sousa (Autor) Outra; Isabel C.F.R. Ferreira (Autor) Outra; Ricardo Calhelha (Autor) Outra; Paula B. Andrade (Autor) FFUP; Patrícia Valentão (Autor) FFUP; Rosa Seabra (Autor) FFUP; Letícia Estevinho (Autor) Outra; Albino Bento (Autor) Outra; José Alberto Pereira (Autor) Outra

Revista

Título: Bioorganic and Medicinal Chemistry

Vol. 14 Nº 24

Páginas: 8533-8538

ISSN: 0968-0896

Editora: Elsevier

Indexação

ISI Web of Science

Classificação Científica

FOS: Ciências médicas e da saúde > Outras ciências médicas

CORDIS: Ciências da Saúde

Outras Informações

Resumo (PT): In the present work, we report the determination of phenolic compounds in ‘alcaparra’ table olives by reversed-phase HPLC/DAD, and the evaluation of their extract in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus), Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Three flavonoidic compounds were identified and quantified: luteolin 7-O-glucoside, apigenin 7-O-glucoside, and luteolin. At low concentrations (0.05 mg/mL) ‘alcaparra’ extract revealed significant inhibition of both Gram positive and Gram negative bacteria growth, with exception of P. aeruginosa. Nevertheless, no antifungal activity was observed at the tested concentrations. <br> <br> <a target="_blank" href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TF8-4KW5W94-3&_user=2460038&_coverDate=12%2F15%2F2006&_rdoc=39&_fmt=high&_orig=browse&_srch=doc-info(%23toc%235220%232006%23999859975%23636631%23FLA%23display%23Volume)&_cdi=5220&_sort=d&_docanchor=&_ct=61&_acct=C000057398&_version=1&_urlVersion=0&_userid=2460038&md5=02f2337f65a83f3efad714250fa9ebbb"> Texto integral </a> <br> <br>

Abstract (EN): In the present work, we report the determination of phenolic compounds in ‘alcaparra’ table olives by reversed-phase HPLC/DAD, and the evaluation of their extract in vitro activity against several microorganisms that may be causal agents of human intestinal and respiratory tract infections, namely Gram positive (Bacillus cereus, Bacillus subtilis, and Staphylococcus aureus), Gram negative bacteria (Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae) and fungi (Candida albicans and Cryptococcus neoformans). Three flavonoidic compounds were identified and quantified: luteolin 7-O-glucoside, apigenin 7-O-glucoside, and luteolin. At low concentrations (0.05 mg/mL) ‘alcaparra’ extract revealed significant inhibition of both Gram positive and Gram negative bacteria growth, with exception of P. aeruginosa. Nevertheless, no antifungal activity was observed at the tested concentrations. <br> <br> <a target="_blank" href="http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TF8-4KW5W94-3&_user=2460038&_coverDate=12%2F15%2F2006&_rdoc=39&_fmt=high&_orig=browse&_srch=doc-info(%23toc%235220%232006%23999859975%23636631%23FLA%23display%23Volume)&_cdi=5220&_sort=d&_docanchor=&_ct=61&_acct=C000057398&_version=1&_urlVersion=0&_userid=2460038&md5=02f2337f65a83f3efad714250fa9ebbb"> Full text </a> <br> <br>

Idioma: Português

Tipo (Avaliação Docente): Científica