Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for the delivery of bioactives sourced from plants: part I - composition and production methods

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2024

Autores

Fathi, F (Autor) Outra; Machado, TOX (Autor) Outra; Kodel, HDC (Autor) Outra; Portugal, I (Autor) Outra; Ferreira, IO (Autor) Outra; Zielinska, A (Autor) Outra; Beatriz B P P Oliveira (Autor) FFUP; Souto, EB (Autor) Outra

Revista

Título: Expert Opinion on Drug Delivery

Vol. 21

Páginas: 1479-1490

ISSN: 1742-5247

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-017-6J5

DOI: 10.1080/17425247.2024.2410951

Abstract (EN): IntroductionNanoparticles (NPs) are widely used in the pharmaceutical field to treat various human disorders. Among these, lipid-based NPs (LNPs), including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), are favored for drug/bioactive delivery due to their high stability, biocompatibility, encapsulation efficiency, and sustained/controlled release. These properties make them particularly suitable as carriers of compounds derived from plant sources.Areas coveredThis study comprehensively explores updated literature knowledge on SLN and NLC, focusing on their composition and production methods for the specific delivery of drug/bioactive compounds derived from plant sources of interest in pharmaceutical and biomedical fields.Expert opinionSLN and NLC facilitate the development of more effective natural product-based therapies, aiming to reduce dosage and minimize side effects. These delivery systems align with the consumer demands for safer and more sustainable products, as there are also based on biocompatible and biodegradable raw materials, thereby posing minimal toxicological risks while also meeting regulatory guidelines.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 12