Graphene-based materials biocompatibility: A review

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

Artur Pinto (Autor) FEUP; Ines C Goncalves (Autor) FEUP; Fernao D Magalhaes (Autor) FEUP

Revista

Título: Colloids and Surfaces B: Biointerfaces

Vol. 111

Páginas: 188-202

ISSN: 0927-7765

Editora: Elsevier

Indexação

ISI Web of Knowledge - 234 Citações

ISI Web of Science

Scopus - 342 Citações

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia dos materiais

CORDIS: Ciências da Saúde > Ciências Médicas ; Ciências Tecnológicas > Engenharia > Engenharia de materiais

Projetos Associados

UI0511 - PROJECTO ESTRATÉGICO - UI 511 - 2013-2014

Outras Informações

ID Authenticus: P-006-6E8

DOI: 10.1016/j.colsurfb.2013.05.022

Abstract (EN): Graphene-based materials (GBMs) have broad potential applications in biomedical engineering and biotechnology. However, existing studies regarding biological effects of GBMs often present contradictory or inconclusive results. This work presents a review of published data in order to provide a critical overview of the state of the art. Firstly, the distinct physical-chemical nature of the GBMs available is clarified, as well as the production methods involved. The review then discusses the available in vitro (with bacterial and mammalian cells) and in vivo studies concerning evaluation of GBMs biocompatibility, as well as existing hemocompatibility studies. The biocompatibility issues concerning composite materials that incorporate GBMs are addressed in a separate section, since encapsulation in a polymer matrix modifies biological interactions. The most pertinent questions that should be addressed in future works are also emphasized.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 15