Aspergillus and other respiratory fungal infections in the ICU: diagnosis and management

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2018

Autores

Paiva, J-A (Autor) FMUP; Mergulhao, P (Autor) FMUP; Pereira, JM (Autor) Outra

Revista

A Revista está pendente de validação pelos Serviços Administrativos.

Título: CURRENT OPINION IN INFECTIOUS DISEASES

Vol. 31

Páginas: 187-193

ISSN: 0951-7375

Editora: Lippincott Williams & Wilkins

Indexação

ISI Web of Knowledge - 5 Citações

Scopus - 5 Citações

Outras Informações

ID Authenticus: P-00N-SA3

DOI: 10.1097/qco.0000000000000436

Abstract (EN): Purpose of review Filamentous fungi respiratory infections, namely because of Aspergillus, Mucorales, Fusarium, or Scedosporium, show rising incidence and occur more in populations which are not classically immunosuppressed. This and their persistent dismal prognosis are the focus of this review. Recent findings Both an early diagnosis, rooted on a high level of suspicion and based on clinical picture, radiology, cultural microbiological exams, fungal biomarkers, PCR and biopsy, and an early therapy, including immunorecovery, whenever possible, good antifungal selection, and surgery for source control, are paramount to maximize the outcome in these diseases. An evolving antifungal armamentarium and a more Pharmacokinetics/Pharmacodynamics-based antifungal prescription may help to improve the prognosis. Summary Improved awareness of these infections may increase the level of suspicion, promoting early diagnosis and treatment, ideally supported with expert stewardship.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7