Mitochondria research and neurodegenerative diseases: On the track to understanding the biological world of high complexity

• Tipo: Artigo em Revista Científica Internacional
• Data: 2022

Autores

Mendes, D (Autor) Outra; Peixoto, F (Autor) Outra; Oliveira, MM (Autor) Outra; Paula B Andrade (Autor) FFUP; Videira, RA (Autor) Outra

Revista

Título: Mitochondrion

Vol. 65

Páginas: 67-79

ISSN: 1567-7249

Editora: Elsevier

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-00W-P1P

DOI: 10.1016/j.mito.2022.05.001

Abstract (EN): From the simple unicellular eukaryote to the highly complex multicellular organism like Human, mitochondrion emerges as a ubiquitous player to ensure the organism's functionality. It is popularly known as the powerhouse of the cell by its key role in ATP generation. However, our understanding of the physiological relevance of mitochondria is being challenged by data obtained in different fields. In this review, a short history of the mitochondria research field is presented, stressing the findings and questions that allowed the knowledge advances, and put mitochondrion as the main player of safeguarding organism life as well as a key to solve the puzzle of the neurodegenerative diseases.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 13