Worldwide Disseminated IncX4 Plasmid Carrying mcr-1 Arrives to Wild Mammal in Portugal

• Tipo: Artigo em Revista Científica Internacional
• Data: 2022

Autores

Palmeira, JD (Autor) Outra; Cunha, MV (Autor) Outra; Helena Sousa (Autor) FFUP; Fonseca, C (Autor) Outra; Torres, RT (Autor) Outra

Revista

Título: Microbiology spectrum

Vol. 10

ISSN: 2165-0497

Editora: American Society for Microbiology

Indexação

ISI Web of Knowledge - 1 Citação

Outras Informações

ID Authenticus: P-00X-N2M

DOI: 10.1128/spectrum.01245-22

Abstract (EN): The mcr-1 gene spread is worldwide recognized as a public health threat at multidrug-resistant infections therapy level. Here, we report for the first time, to the best of our knowledge, the detection of the globally distributed IncX4 plasmid carrying mcr-1 (mcr-1/IncX4) in Escherichia coli isolated from a wild mammal in Portugal and Europe. This plasmid was found in a ST533 E. coli isolate with a multidrug-resistant profile, virulence potential, and possibly phylogenetically related to human isolates. Our work contributes to highlight the importance of antimicrobial resistance (AMR) surveillance in wildlife, an important compartment of the whole ecosystem often overlooked in the fight against AMR.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5