Effect of stainless steel corrosion products on in vitro biomineralization

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 1999

Autores

Fernandes MH (Autor) FMDUP

Revista

Título: Journal of Biomaterials Applications

Vol. 14

Páginas: 113-168

ISSN: 0885-3282

Editora: SAGE

Indexação

ISI Web of Knowledge - 18 Citações

Scopus - 21 Citações

Outras Informações

ID Authenticus: P-001-36Z

Abstract (EN): Osteoblast-like cell cultures have been used as in vitro models to study the interactions of bone tissue with biomaterials and their degradation products. This work reviews the effects of AISI 316L stainless steel (SS) corrosion products on the osteoblastic behavior of rat and human bone cell cultures. Results suggest that such products affect, in a dose-]dependent manner, the proliferation and differentiation of osteoblastic cells; these effects depend on the developmental stage of the osteoblastic cells. Above certain nonlethal concentrations, SS corrosion products prevent the mineralization of the extracellular matrix, a process that reflects the complete expression of the osteoblastic phenotype.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 56