Characterization and Shelf Life of beta-Carotene Loaded Solid Lipid Microparticles Produced With Stearic Acid and Sunflower Oil

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

de Lara Gomes, GVD (Autor) Outra; Borrin, TR (Autor) Outra; Cardoso, LP (Autor) Outra; Souto, E (Autor) Outra; de Pinho, SC (Autor) Outra

Revista

Título: Brazilian Archives of Biology and Technology

Vol. 56

Páginas: 663-671

ISSN: 1516-8913

Editora: Instituto de Tecnologia do Paraná

Indexação

ISI Web of Knowledge - 16 Citações

Scopus - 22 Citações

Outras Informações

ID Authenticus: P-008-EZD

DOI: 10.1590/s1516-89132013000400017

Abstract (EN): Solid lipid microparticles were tested as microencapsulation systems for protecting beta-carotene from degradation. Blends of long-chain (C18) solid lipids (70% stearic acid) and sunflower oil (30%) were used to produce lipid microparticles encapsulating the carotenoid. Polysorbate 80 (4%) was employed to stabilize the stearic acid microparticles. The concentration of beta-carotene was monitored using spectrophotometry, the particle size distribution was measured by laser diffraction, the crystal structure was determined by wide angle X-ray diffraction (WAXD), and the thermal behaviour was characterized by differential scanning calorimetry (DSC) over a period of seven months. All of the systems had an average particle size smaller than 5 mu m. To avoid beta-carotene oxidation, alpha-tocopherol was added to the formulations and its action as an oxygen trap was crucial for the antioxidant effect. For stearic-acid microparticles with alpha-tocopherol, more than 90% of the initial amount of beta-carotene was preserved after seven months under refrigerated storage (7-10 degrees C) in the dark. Significant microstructural alterations were detected using WAXD and DSC only in the stearic acid microparticles without alpha-tocopherol. These results seemed promising and suggested that the blends of long-chain solid lipids and liquid lipids were suitable for the production of stable solid lipid microparticles.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9