Perspectives in Nanomedicine-Based Research Towards Cancer Therapies

• Tipo: Artigo em Revista Científica Internacional
• Data: 2011

Autores

Rane, YM (Autor) Outra; Souto, EB (Autor) Outra

Revista

Título: Current Nanoscience

Vol. 7

Páginas: 142-152

ISSN: 1573-4137

Editora: Bentham Science

Indexação

ISI Web of Knowledge - 4 Citações

Scopus - 4 Citações

Outras Informações

ID Authenticus: P-002-SNK

DOI: 10.2174/157341311794653640

Abstract (EN): Nanomedicine is focused on the development of submicrometer carriers designed for improving the biodistribution of systemically administered drugs. Nanoparticles have been exploited for immunoassays, immunohistochemistry, cancer diagnostics, bioseparation of specific cell populations, and cellular imaging. Public awareness on the use of these novel therapeutic approaches is increasing due to the exponential boom of nanotechnologies in the latest years. With respect to cancer therapy, several tumour-targeted nanomedicines have been evaluated over the years, and there is a clear evidence for substantial improvement of the therapeutic index of anti-neoplastics. The present review addresses the most relevant targeting strategies, discussing the major public awareness, therapeutic advances and future directions in the development of tumour-targeted nanomedicines.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11