A New Control Scheme for Neuromuscular Blockade with Optimal Initialization Time

• Tipo: Artigo em Livro de Atas de Conferência Internacional
• Data: 2022

Autores

Nogueira, D (Autor) Outra; Mendonca, T (Autor) FCUP; Rocha, P (Autor) FEUP

Ata de Conferência Internacional

Título: CONTROLO 2022

Páginas: 310-319

15th APCA International Conference on Automatic Control and Soft Computing (CONTROLO)

Caparica, PORTUGAL, JUL 06-08, 2022

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 0 Citações

Outras Informações

ID Authenticus: P-00X-031

DOI: 10.1007/978-3-031-10047-5_27

Abstract (EN): A new strategy is proposed for the automatic control of the neuromuscular blockade during general anesthesia by means of the continuous infusion of rocuronium. This strategy is based on the reduced parameter Wiener model proposed in M. M. Da Silva, T. Mendonca, and T. Wigren, Nonlinear adaptive control of the NeuroMuscular Blockade in anesthesia, Proc. IEEE Conf. Decis. Control December 2011, pp. 41-46, 2011, https://doi.org/10.1109/CDC.2011.616 0227. One of its most important features is taking into account the usual clinical procedures, namely, the administration of an initial bolus at the beginning of the surgery prior to the delivery of the anesthetic by continuous infusion. The proposed controller for the continuous drug infusion process is designed in order to track a desired reference level of neuromuscular blockade. It is based on steady-state model inversion with suitable pole placement in order to accelerate convergence. Moreover, the controller is put into action at an optimal initialization time in order to minimize the tracking error.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 10