Reduced graphene oxide-nickel nanoparticles/biopolymer composite films for the sub-millimolar detection of glucose

• Tipo: Artigo em Revista Científica Internacional
• Data: 2016

Autores

Krishna, R (Autor) Outra; Jose M Campina (Autor) FCUP; Fernandes, PMV (Autor) Outra; ventura, j. (Autor) FCUP; Titus, E (Autor) Outra; Silva, F (Autor) FCUP

Revista

Título: The Analyst

Vol. 141

Páginas: 4151-4161

ISSN: 0003-2654

Editora: Royal Society of Chemistry

Indexação

ISI Web of Knowledge - 7 Citações

Scopus - 9 Citações

Outras Informações

ID Authenticus: P-00K-KQ3

DOI: 10.1039/c6an00475j

Abstract (EN): Hybrid conjugates of graphene with metallic/semiconducting nanostructures can improve the sensitivity of electrochemical sensors due to their combination of well-balanced electrical/electrocatalytic properties and superior surface-to-volume ratio. In this study, the synthesis and physical characterization of a hybrid conjugate of reduced graphene oxide and nickel nanoparticles (rGO-Ni NPs) is presented. The conjugate was further deposited onto a glassy carbon electrode as a nanocomposite film of chitosan and glucose oxidase. The electrochemical response and morphology of the films were investigated using SEM, CV, and EIS, and their applications as a glucose biosensor explored for the first time in proof-of-concept tests. The low operating potential along with the good linearity and sensitivity (up to 129 mu A cm(-2) mM(-1)) found in the sub-millimolar range suggest potential applications in the self-management of hypoglycemia from blood samples or in the development of non-invasive assays for body fluids such as saliva, tears or breath.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11