First principles model of the transformation of hydroxyapatite into brushite and growth of brushite

• Tipo: Artigo em Livro de Atas de Conferência Internacional
• Data: 2005

Autores

Cristina Oliveira (Autor) FEUP; Petia Georgieva (Autor) FEUP; Fernando Rocha (Autor) FEUP; António Ferreira (Autor) FEUP; Sebastião Feyo de Azevedo (Autor) FEUP

Ata de Conferência Internacional

Título: ChemPor 2005

Páginas: 297-298

9th International Chemical Engineering Conference

Coimbra, Portugal, 21 a 23 de Setembro de 2005

Classificação Científica

FOS: Ciências da engenharia e tecnologias > Engenharia química

CORDIS: Ciências Tecnológicas > Engenharia > Engenharia química

Outras Informações

Abstract (EN): In this paper, a dynamical first principles model of the precipitation of hydroxyapatite (HAP) into brushite and growth of brushite is developed. The process itself is challenging since it consists of multiple phases and there exists strong nonlinear and dynamic effects between the variables. However, our objective was to build a comparatively simple and reliable model to explain the dynamical behaviour of the process. Based upon a databank of laboratory measurements of the calcium concentration in solution (on-line) and the particle size distribution (off-line) an unified model of the process for a gamma of initial concentrations of the reagents was derived as a system of ordinary differential equations of time. The performance of the model is examined with respect to prediction quality of the time trajectories of mass of calcium in solution and the average (in mass) particle size.

Idioma: Inglês

Tipo (Avaliação Docente): Científica