The "PIP Problem": Clinical and Histologic Characteristics

• Tipo: Artigo em Revista Científica Internacional
• Data: 2013

Autores

Correia Sa, I (Autor) Outra; Rodrigues Pereira, P (Autor) Outra; Marisa Marques (Autor) FMUP

Revista

Título: Aesthetic Plastic Surgery

Vol. 37

Páginas: 936-940

ISSN: 0364-216X

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 3 Citações

Scopus - 4 Citações

Outras Informações

ID Authenticus: P-006-71P

DOI: 10.1007/s00266-013-0196-z

Abstract (EN): Implants from Poly Implant Proth,se (PIP), the French manufacturer, showed increased risk of implant rupture and silicone leakage through the shell. Concerns also exist about the potential irritant behavior of silicone gel filler in these implants. This report presents the clinical, histologic, and microbiologic characteristics of a capsule and a siliconoma from a patient with a ruptured PIP implant. A 41-year-old woman submitted to breast augmentation in 2005 with PIP silicone gel implants presented with a recent history of progressive asymmetric breast enlargement and an enlarged lymph node on her right axilla. No capsular contracture was observed. A breast ultrasonography showed intra- and extracapsular ruptures of the right implant. The woman underwent explantation. Histologic analysis of the breast capsules showed a thin capsule with a chronic, mild inflammatory response. Microbiologic analysis showed no bacterial agent. The irritant behavior of the PIP silicone gel previously described was not able to produce capsular contracture or an exuberant inflammatory reaction. Studies to evaluate the potential risks of the silicone gel and to define the hazards for women implanted with those prostheses are urgently needed. This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 5