High Prevalence of Human Papillomavirus on Anal and Oral Samples from Men and Women with External Anogenital Warts: The HERCOLES Study

• Tipo: Artigo em Revista Científica Internacional
• Data: 2019

Autores

Carmen Silva (Autor) FMUP; Santo, I (Autor) Outra; Azevedo, J (Autor) Outra; Azevedo L (Autor) FMUP; Pista, Â (Autor) Outra; Dias C (Autor) FMUP; Cunha, MJ (Autor) Outra

Revista

Título: Acta Dermato-Venereologica

Vol. 99

Páginas: 557-563

ISSN: 0001-5555

Editora: Medical Journals/Acta D-V

Indexação

ISI Web of Knowledge - 8 Citações

Scopus - 9 Citações

Outras Informações

ID Authenticus: P-00Q-5Z4

DOI: 10.2340/00015555-3136

Abstract (EN): Human papillomavirus (HPV) infection is highly prevalent in the sexually active population. This study estimates the prevalence of HPV DNA in anal and oral samples from a cohort of men and women with incident anogenital warts. Anal and/ or oral samples from 541 patients with anogenital warts were tested for 35 HPV genotypes using a PCR assay. The overall prevalence of anal HPV and oral HPV DNA was 59.9% (n = 305/ 509; 95% confidence interval (CI) 55.664.1%) and 14.5% (n = 78/ 538; 95% CI 11.8-17.7%), respectively. Among patients with perianal warts, the anal HPV DNA prevalence was 92.3% (95% CI 87.095.5%). Anal HPV DNA prevalence in patients with genital warts but no perianal warts was 55.7% (95% CI 50.6-60.7%). Both anal and oral HPV infections were more common in men who have sex with men than in heterosexual men (90.4% versus 38.5% and 20.8% versus 11.8%, respectively). Anal high risk-HPV infection was more common in women (58.8%) and in men who have sex with men (67.7%). We found that anogenital warts represent a clinical marker for both anal and oral HPV infections, including anal high risk-HPV infections, particularly among women and men who have sex with men.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7