Spectrum of Pediatric Cancers in Mozambique: An Analysis of Hospital and Population-Based Data

• Tipo: Artigo em Revista Científica Internacional
• Data: 2014

Autores

Carreira, H (Autor) Outra; Lorenzoni, C (Autor) Outra; Carrilho, C (Autor) Outra; Ferro, J (Autor) Outra; Sultane, T (Autor) Outra; Garcia, C (Autor) Outra; Amod, F (Autor) Outra; Augusto, O (Autor) Outra; Silva Matos, C (Autor) Outra; La Vecchia, C (Autor) Outra; Lunet N (Autor) FMUP

Revista

Título: Pediatric Hematology and Oncology

Vol. 31

Páginas: 498-508

ISSN: 0888-0018

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 5 Citações

Scopus - 5 Citações

Outras Informações

ID Authenticus: P-009-SD5

DOI: 10.3109/08880018.2014.909547

Abstract (EN): The existing data provide little detail about the epidemiology of pediatric cancers in Mozambique. We aimed at characterizing the spectrum of pediatric cancers (0-14 years) diagnosed in Mozambique in two different calendar periods. Data were obtained from the Pathology Department of the Maputo Central Hospital (DP-HCM) (1999-2000 and 2009-2010), which receives virtually all samples for histopathological diagnosis in Maputo, with the exception of leukemia, and from the population-based Cancer Registry of Beira (2009-2010). In 1999-2000, the DP-HCM diagnosed 61 cancers. Burkitt lymphoma, malignant bone tumors, and rhabdomyosarcomas accounted for 24.6%, 11.5%, and 9.8% of all cases, respectively. In 2009-2010, the number of cancers increased to 150, reflecting a two-to threefold increase in the proportion of Kaposi sarcomas, non-Hodgkin lymphomas, nephroblastomas, and neuroblastomas. In 2009-2010, the Cancer Registry of Beira registered 34 cases, corresponding to an incidence rate of 9.7/100,000 inhabitants in this age group; Kaposi sarcomas, lymphomas, retinoblastomas, and nephroblastomas accounted for 29.4%, 23.5%, 8.8%, and 8.8% of all cases, respectively. These data show that pediatric cancers account for an appreciable burden in Mozambique, probably reflecting a high frequency of HIV-associated cancers and improved access to diagnosis, and highlight the potential for improving surveillance in this low resource setting.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11