Bioactive peptides in ovine and caprine cheeselike systems prepared with proteases from Cynara cardunculus

• Tipo: Artigo em Revista Científica Internacional
• Data: 2006

Autores

Silva, SV (Autor) Outra; Pihlanto, A (Autor) Outra; F. Xavier Malcata (Autor) Outra

Revista

Título: Journal of Dairy Science

Vol. 89 Nº 7

Páginas: 3336-3344

ISSN: 0022-0302

Editora: Elsevier

Indexação

ISI Web of Knowledge - 62 Citações

Scopus - 82 Citações

Outras Informações

ID Authenticus: P-004-HKF

Abstract (EN): The potential angiotensin-converting enzyme (ACE) inhibitory and antioxidant activities of peptides in water-soluble extracts, obtained from raw and sterilized ovine and caprine cheeselike systems coagulated with enzymes from the plant Cynara cardunculus, were assessed. Prior to the assay, the 3,000-Da permeate from 45-d-old cheeselike systems was fractionated by tandem chromatographic techniques. Several peaks were obtained in each chromatogram, but only some were associated with ACE-inhibitory or antioxidant activity or both. Peptides Tyr-Gln-Glu-Pro, Val-Pro-Lys-Val-Lys, and Tyr-Gln-Glu-Pro-Val-Leu-Gly-Pro-* from beta-casein, as well as Arg-Pro-Lys and Arg-Pro-Lys-His-Pro-Ile-Lys-His-* from alpha(s1)-casein exhibited ACE-inhibitory activity. Peptides released upon cleavage of the peptide bond Leu190-Tyr191 (either in ovine or caprine beta-casein), and corresponding to the beta-casein sequence Tyr-Gln-Glu-Pro-*, possessed antioxidant activity.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9