The Effect of Bariatric Surgery Type on Lipid Profile: An Age, Sex, Body Mass Index and Excess Weight Loss Matched Study

• Tipo: Artigo em Revista Científica Internacional
• Data: 2016

Autores

Cunha, FM (Autor) Outra; Oliveira, J (Autor) Outra; John Preto (Autor) Outra; Saavedra, A (Autor) Outra; Costa, MM (Autor) Outra; Magalhes, D (Autor) Outra; Lau, E (Autor) Outra; Bettencourt Silva, R (Autor) Outra; Freitas, P (Autor) FMUP; Varela, A (Autor) Outra; Carvalho, Davide (Autor) FMUP

Revista

Título: Obesity Surgery

Vol. 26

Páginas: 1041-1047

ISSN: 0960-8923

Editora: Springer Nature

Indexação

ISI Web of Knowledge - 46 Citações

Scopus - 48 Citações

Outras Informações

ID Authenticus: P-00G-E3R

DOI: 10.1007/s11695-015-1825-1

Abstract (EN): Bariatric surgery improves lipid profile. A still unanswered question is whether this improvement is merely weight-dependent or also results from factors inherent to specificities of the bariatric procedure. We aimed to study lipid profile 1 year after bariatric surgery and compare its changes between the different procedures in patients matched for initial weight and weight loss. We retrospectively analysed patients submitted to Roux-en-Y gastric bypass (RYGB), adjustable gastric banding (AGB) or sleeve gastrectomy (SG) between 2010 and 2013. Patients were matched for age (+/- 5 years), sex, pre-surgery body mass index (BMI) (+/- 2 Kg/m(2)) and excess weight loss (EWL) (+/- 5 %). Baseline and 1-year lipid profile, its variation and percentage of variation was compared between surgeries. We analysed 229 patients: 72 pairs RYGB-AGB, 47 pairs RYGB-SG and 33 pairs AGB-SG. The median age was 41 (35-52) years and 11.8 % were male. Pre-operative BMI was 44.0 +/- 4.6 and 32.1 +/- 4.4 Kg/m(2) at 1 year. EWL at 1 year was 64.2 +/- 18.9 %. There were no differences in baseline lipid profile between patients submitted to different types of bariatric surgery. At 1 year, high-density lipoprotein cholesterol (HDL) and triglycerides (TG) improved similarly with all surgeries. Total cholesterol (TC) and low-density lipoprotein cholesterol (LDL) at 1 year decreased significantly more in patients submitted to RYGB than in weight-matched patients undergoing AGB or SG. RYGB is the only bariatric surgery that reduces TC and LDL in age-, sex-, BMI- and EWL-matched patients. All three procedures improved TG and HDL similarly when the confounding effect of weight loss is eliminated.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7