Challenges in Cytology Specimens With Hurthle Cells

• Tipo: Artigo em Revista Científica Internacional
• Data: 2021

Autores

Thodou, E (Autor) Outra; Canberk, S (Autor) Outra; Fernando Schmitt (Autor) FMUP

Revista

Título: Frontiers In Endocrinology

Vol. 12

ISSN: 1664-2392

Editora: Frontiers Media

Indexação

ISI Web of Knowledge - 8 Citações

Outras Informações

ID Authenticus: P-00V-6AB

DOI: 10.3389/fendo.2021.701877

Abstract (EN): In fine-needle aspirations (FNA) of thyroid, Hurthle cells can be found in a broad spectrum of lesions, ranging from non-neoplastic conditions to aggressive malignant tumors. Recognize them morphologically, frequently represents a challenging for an adequately diagnosis and are associated with a significant interobserver variability. Although the limitations of the morphologic diagnosis still exist, the interpretation of the context where the cells appear and the recent advances in the molecular knowledge of Hurthle cells tumors are contributing for a more precise diagnosis. This review aims to describe the cytology aspects of all Hurthle cells neoplastic and non-neoplastic thyroid lesions, focusing on the differential diagnosis and reporting according to The Bethesda System for Reporting Thyroid Cytology (TBSRTC). New entities according to the latest World Health Organization (WHO) classification are included, as well as an update of the current molecular data.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11