Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature

• Tipo: Artigo em Revista Científica Internacional
• Data: 2002

Autores

Reis, JS (Autor) Outra; Milanezi, F (Autor) Outra; Soares, MF (Autor) Outra; Fillus Neto, J (Autor) Outra; Fernando Schmitt (Autor) FMUP

Revista

Título: Journal of Cutaneous Pathology

Vol. 29

Páginas: 59-62

ISSN: 0303-6987

Editora: Wiley-Blackwell

Indexação

ISI Web of Knowledge - 33 Citações

Scopus - 45 Citações

Outras Informações

ID Authenticus: P-000-REP

DOI: 10.1034/j.1600-0560.2002.290112.x

Abstract (EN): Background: Spindle cell/pleomorphic lipoma (SC/PL) is a benign adipose tissue tumor that usually affects the subcutaneous tissues of shoulders, backs, and neck region of middle-aged male patients. Histologically, it is characterized by the presence of primitive CD34-positivc spindle cells arranged in short fascicles, bizarre floret-like multinucleated giant cells, mature adipocytes, and a small number of lipoblasts. Recently, air intradermal subset has been described, which mainly affects female patients and presents a wider antomical distribution when compared to the classical variant of SC/PL. Methods: We report a case, of intradermal SC/PL affecting the labium majus of a 56-year-old female patient. Results: The histological examination disclosed the typical histological features, however the lesion showed poorly demarcated and infiltrative borders, as well as involvement of dermal nerves. The immunohistochemical analysis according to streptovidin-biotin-peroxidase technique showed immunoreactivity for CD34 and vimentin in the spindle cells, as well as S100 protein and vimentin in the adipocytic cells. Conclusions: To the best of our knowledge, this is the first case of intradermal SC/PL affecting the vulvar region. Care must be taken not to misdiagnosis this rare tumor as well-differentiated liposarcoma, cellular angiofibroma, solitary fibrous tumor, and cutaneous neurofibroma.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 4