Benign and malignant apocrine lesions of the breast

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2012

Autores

Gerhard, R (Autor) Outra; Costa, JL (Autor) Outra; Fernando Schmitt (Autor) FMUP

Revista

Título: Expert Review of Anticancer Therapy

Vol. 12

Páginas: 215-221

ISSN: 1473-7140

Editora: Taylor & Francis

Indexação

ISI Web of Knowledge - 7 Citações

Scopus - 9 Citações

Outras Informações

ID Authenticus: P-002-DBW

DOI: 10.1586/era.11.213

Abstract (EN): Apocrine differentiation occurs in a variety of breast lesions, both benign and malignant. This review is a reflection of our critical view of the recent advances towards the understanding of this particular type of breast lesions. Focus is given to the histological criteria that allow their reproductive identification, with additional attention to the recent microarray studies. These describe the recent molecular classification of breast cancer and identify an apocrine molecular subtype that opens the door for new putative therapies for this particular type of tumor. Indeed we anticipate that the determination of androgen receptor will enter into the routine assessment of breast cancer cases and become a surrogate marker for treatment in apocrine triple-negative breast cancer.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7