Computational Studies of the Luciferase Light-Emitting Product: Oxyluciferin

• Tipo: Artigo em Revista Científica Internacional
• Data: 2011

Autores

da silva, lp (Autor) Outra; da silva, jcge (Autor) FCUP

Revista

Título: Journal of Chemical Theory and Computation

Vol. 7 Nº 4

Páginas: 809-817

ISSN: 1549-9618

Editora: American Chemical Society

Indexação

ISI Web of Knowledge - 68 Citações

Scopus - 77 Citações

Classificação Científica

FOS: Ciências exactas e naturais > Química

CORDIS: Ciências Físicas > Química > Química analítica > Espectroquímica

Outras Informações

ID Authenticus: P-002-SQV

DOI: 10.1021/ct200003u

Abstract (EN): Firefly luciferase is the most studied bioluminescence system, and its catalyzed reactions have been relatively well characterized. However, the color tuning mechanism that leads to firefly multicolor bioluminescence is still unknown, nor is consensual which is the yellow-green and red emitters. Computational studies have been essential in the study of oxyluciferin (OxyLH(2)) chemi- and bioluminescence and are responsible for most of our knowledge of this natural phenomenon. The objective of this manuscript is the analysis of the benefits and the conclusions derived from the theoretical studies of the light emitter, OxyLH(2), and its applications on bioluminescence research.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 9