Changing trends in the prevalence of diabetic retinopathy in type 1 diabetes mellitus from 1990 to 2018: A retrospective study in a Portuguese population

• Tipo: Artigo em Revista Científica Internacional
• Data: 2019

Autores

Madeira, C (Autor) Outra; Lopes, M (Autor) Outra; Laiginhas, R (Autor) Outra; Neves, J (Autor) FMUP; Rosas, V (Autor) Outra; Barbosa, M (Autor) Outra; Carvalho, Davide (Autor) FMUP; Falcão-Reis F (Autor) FMUP; Manuel Falcão (Autor) FMUP

Revista

Título: Diabetes Research and Clinical Practice

Vol. 158

ISSN: 0168-8227

Editora: Elsevier

Indexação

ISI Web of Knowledge - 5 Citações

Scopus - 4 Citações

Outras Informações

ID Authenticus: P-00R-BWD

DOI: 10.1016/j.diabres.2019.107891

Abstract (EN): Purpose: To estimate the prevalence of diabetic retinopathy /(DR) in a Portuguese population with type 1 diabetes (T1DM). Methods: Retrospective review of all patients with T1DM, whose reference center was Centro Hospitalar de Sao Joao, a tertiary center in Portugal, who were diagnosed between 1990 and 2018. DR was classified based on fundus examination in medical records as (0) no evidence of retinopathy, (1) mild non-proliferative retinopathy (NPDR); (2) moderate to severe non-proliferative retinopathy (NPDR) and (3) proliferative retinopathy (PDR). Patients were classified according to the eye with a worse retinopathy stage. Follow-up was considered as time between the diagnosis of diabetes and the last funduscopic evaluation. Results: 233 patients met the inclusion and exclusion criteria. The prevalence of any DR at less than 5, 10, 15, 20 and more than 20-years of DM was 1.8%, 10.4%, 34.8%, 54.1% and 71.2% respectively. The overall prevalence of DR was 43.3% (n = 101). At the last observation, 43 patients (18.5%) had mild NPDR, 34 patients (14.6%) had moderate to severe NPDR and 24 patients (10.3%) had PDR. The longer the disease duration, the higher the number of patients with DR. Conclusion: The prevalence of DR in our cohort was 34.8% after 15 years of systemic disease and 54.1% after 20 years, which is lower than what has been reported in the literature. Further multicentric prospective studies, are needed to clarify changes in the epidemiology of DR in type 1 diabetics.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7