Quantification of the Animal Tuberculosis Multi-Host Community Offers Insights for Control

• Tipo: Artigo em Revista Científica Internacional
• Data: 2020

Autores

Gortazar, C (Autor) Outra; Santos, N (Autor) Outra; Richomme, C (Autor) Outra; Nunes, T (Autor) Outra; Vicente, J (Autor) Outra; Alves, PC (Autor) FCUP; de la Fuente, J (Autor) Outra; Correia Neves, M (Autor) Outra; Boschiroli, ML (Autor) Outra; Delahay, R (Autor) Outra

Revista

Título: Pathogens

Vol. 9

Página Final: 421

Editora: MDPI

Indexação

ISI Web of Knowledge - 29 Citações

Scopus - 28 Citações

Outras Informações

ID Authenticus: P-00S-8F5

DOI: 10.3390/pathogens9060421

Abstract (EN): Animal tuberculosis (TB) is a multi-host zoonotic disease whose prevalence in cattle herds in Europe has been increasing, despite a huge investment in eradication. The composition of the host community is a fundamental driver of pathogen transmission, and yet this has not been formally quantified for animal TB in Europe. We quantified multi-host communities of animal TB, using stochastic models to estimate the number of infected domestic and wild hosts in three regions: officially TB-free Central-Western Europe, and two largely TB-endemic regions, the Iberian Peninsula and Britain and Ireland. We show that the estimated number of infected animals in the three regions was 290,059-1,605,612 and the numbers of infected non-bovine domestic and wild hosts always exceeded those of infected cattle, with ratios ranging from 3.3 (1.3-19.6):1 in Britain and Ireland to 84.3 (20.5-864):1 in the Iberian Peninsula. Our results illustrate for the first time the extent to which animal TB systems in some regions of Europe are dominated by non-bovine domestic and wild species. These findings highlight the need to adapt current strategies for effective future control of the disease.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 11