Characterization of the pJB12 Plasmid from Pseudomonas aeruginosa Reveals Tn6352, a Novel Putative Transposon Associated with Mobilization of the bla(VIM-2)-Harboring In58 Integron

• Tipo: Artigo em Revista Científica Internacional
• Data: 2017

Autores

Botelho, J (Autor) Outra; Grosso, F (Autor) Outra; Luisa Peixe (Autor) FFUP

Revista

Título: Antimicrobial Agents and Chemotherapy

Vol. 61

ISSN: 0066-4804

Editora: American Society for Microbiology

Indexação

ISI Web of Knowledge - 12 Citações

Scopus - 15 Citações

Outras Informações

ID Authenticus: P-00M-QVT

DOI: 10.1128/aac.02532-16

Abstract (EN): The bla(VIM-2)-carrying In58 integron has been linked to a chromosomal location in different bacterial species, including Pseudomonas aeruginosa. This work reports the first fully sequenced In58-harboring plasmid, which is significantly different from the two previously identified bla(VIM-2)-carrying plasmids in P. aeruginosa. bla(VIM-2) might have been acquired by transposition of Tn6352, a novel transposon composed of the In58 and ISPa17 elements. The recognition of similar inverted repeat (IR) sites by ISPa17 reveals a common mobilization process associated with acquisition of the bla(VIM-2) and bla(VIM-1) genes.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 6