Allelle frequencies of six miniSTR loci in the population of Northern Portugal

• Tipo: Outra Publicação em Revista Científica Internacional
• Data: 2008

Autores

Laura Cainé (Colaborador) FMUP

Revista

Título: Forensic Science International: Genetics

Vol. 2

Páginas: 379-381

ISSN: 1872-4973

Editora: Elsevier

Indexação

ISI Web of Knowledge - 6 Citações

Scopus - 7 Citações

Outras Informações

ID Authenticus: P-003-WG9

DOI: 10.1016/j.fsigen.2008.05.003

Abstract (EN): A possible approach to try to recover information from degraded DNA is to reduce the size of the PCR products by designing primers that bind as close as possible to the STR repeat region, known as miniSTRs. Allele frequencies and forensic parameters for the six miniSTRs loci D I S 1677, D2S441, D4S2364, D10S1248, D14S1434 and D22S1045 were investigated in a sample group consisting of 228 anonymous apparently healthy unrelated individuals living in North of Portugal. The results show that all loci were in Hardy-Weinberg equilibrium. The combined power of discrimination and power of exclusion for the six loci were 0.99999 and 0.9789, respectively. All but one (D4S2364) loci showed a moderate degree of polymorphism (observed heterozygosity >0.6). The allele sizes ranged between 66 and 118 bp in our population, which is beneficial for typing degraded samples than those of a commercial STR kit.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3