Gangrene of the fingertips after bleomycin and methotrexate

• Tipo: Artigo em Revista Científica Internacional
• Data: 2000

Autores

Correia, O (Autor) Outra; Ribas, F (Autor) Outra; Azevedo, R (Autor) Outra; Rodrigues, H (Autor) Outra; Delgado, L (Autor) FMUP

Revista

Título: Cutis

Vol. 66

Páginas: 271-+

ISSN: 0011-4162

Editora: Quadrant HealthCom

Indexação

ISI Web of Knowledge - 3 Citações

Scopus - 9 Citações

Outras Informações

ID Authenticus: P-000-YT6

Abstract (EN): The increased use of cytostatic drugs, which are sometimes used in combination chemotherapy, may result in new and unusual cutaneous side effects. We describe a 57-year-old man with acral erythrocyanosis progressing to acute digital ischemia and gangrene that developed after combined chemotherapy (bleomycin and methotrexate) used to treat a metastatic squamous cell carcinoma of the hypopharynx. A leukocyloclastic vasculitis was found in both the acute phase and in the amputated fingertips. This supports the well-reported potential of bleomycin to trigger acral vascular toxicity.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 3