Magnetron co-sputtered TiO2/SiO2/Ag nanocomposite thin coatings inhibiting bacterial adhesion and biofilm formation

• Tipo: Artigo em Revista Científica Internacional
• Data: 2020-01-02

Autores

Todorka Vladkova (Autor) Outra; Orlin Angelov (Autor) Outra; Dragomira Stoyanova (Autor) Outra; Dilyana Gospodinova (Autor) Outra; Luciana Gomes (Autor) FEUP; Alexandra Soares (Autor) Outra; Filipe Mergulhão (Autor) FEUP; Iliana Ivanova (Autor) Outra

Revista

Título: Surface and Coatings Technology

Vol. 384

ISSN: 0257-8972

Editora: Elsevier

Indexação

ISI Web of Knowledge - 0 Citações

Scopus - 11 Citações

Outras Informações

ID Authenticus: P-00R-HZC

DOI: 10.1016/j.surfcoat.2019.125322

Abstract (EN): Aim of this study is the development of new functional coatings for medical devices, using magnetron co-sputtering to deposit triple TiO2/SiO2/Ag nanocomposite thin films with expected antimicrobial activity. Some surface characteristics (elemental composition, hydrophilic/hydrophobic balance, surface energy and topography) were estimated to look for correlation with bacterial cells growth and biofilm formation on TiO2/SiO2/Ag coated samples. Strong inhibitory effect toward Escherichia coli growth was found: the number of viable bacterial cells approaches to zero at the first 30 min -1 h, depending on the Ag content. Biofilm formation in urine flow at 48 h is reduced down to 92% compared to a control glass surface. Direct contact and eluted silver mediated killing were experimentally demonstrated as mechanisms of antibacterial action of the TiO2/SiO2/Ag coatings. These coatings are promising candidate for antimicrobial protection of urinary tract devices for at least 48 h, suggesting benefits over longer time.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 7