SPECIATION IN THE EUROPEAN RABBIT (ORYCTOLAGUS CUNICULUS): ISLANDS OF DIFFERENTIATION ON THE X CHROMOSOME AND AUTOSOMES

• Tipo: Artigo em Revista Científica Internacional
• Data: 2010

Autores

Carneiro, M (Autor) Outra; Blanco Aguiar, JA (Autor) Outra; Villafuerte, R (Autor) Outra; ferrand, n (Autor) FCUP; Nachman, MW (Autor) Outra

Revista

Título: EVOLUTION

Vol. 64

Páginas: 3443-3460

ISSN: 0014-3820

Editora: Wiley-Blackwell

Indexação

ISI Web of Knowledge - 64 Citações

Scopus - 63 Citações

Outras Informações

ID Authenticus: P-003-0G3

DOI: 10.1111/j.1558-5646.2010.01092.x

Abstract (EN): Studies of gene flow between closely related taxa can provide insight into the genetic basis of speciation. To evaluate the importance of the X chromosome in reproductive isolation between subspecies of the European rabbit and to study the genomic scale over which islands of differentiation extend, we resequenced a total of 34 loci distributed along the X chromosome and chromosome 14. Previous studies based on few markers suggested that loci in centromeric regions were highly differentiated between rabbit subspecies, whereas loci in telomeric regions were less differentiated. Here, we confirmed this finding but also discovered remarkable variation in levels of differentiation among loci, with F(ST) values from nearly 0 to 1. Analyses using isolation-with-migration models suggest that this range appears to be largely explained by differential levels of gene flow among loci. The X chromosome was significantly more differentiated than the autosomes. On chromosome 14, differentiation decayed very rapidly at increasing distances from the centromere, but on the X chromosome distinct islands of differentiation encompassing several megabases were observed both at the centromeric region and along the chromosome arms. These findings support the idea that the X chromosome plays an important role in reproductive isolation between rabbit subspecies. These results also demonstrate the mosaic nature of the genome at species boundaries.

Idioma: Inglês

Tipo (Avaliação Docente): Científica

Nº de páginas: 18